Protein Overview: ADML_RAT

General Information:
Name(s) found:	ADML_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6978507\|ref\|NP_036847.1\| adrenomedullin precursor [Rattus norvegicus] [NCBI NR] pir\|\|JN0766 adrenomedullin precursor - rat [NCBI NR] gi\|440380\|dbj\|BAA03665.1\| adrenomedullin precursor [Rattus norvegicus] [NCBI NR] gi\|38197392\|gb\|AAH61775.1\| Adrenomedullin [Rattus norvegicus] [NCBI NR] gi\|149068311\|gb\|EDM17863.1\| adrenomedullin, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|1168360\|sp\|P43145.1\|ADML_RAT RecName: Full=ADM; Contains: RecName: Full=Adrenomedullin; Short=AM; Contains: RecName: Full=Proadrenomedullin N-20 terminal peptide; AltName: Full=ProAM N-terminal 20 peptide; Short=ProAM-N20; Short=PAMP; Flags: Precursor [NCBI NR] gi\|1098504\|gb\|AAB60519.1\| adrenomedullin [NCBI NR] ADM OS=Rattus norvegicus GN=Adm PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):None ADM precursor [Contains: Adrenomedullin [hmr_yeast5_DM3-1_pombe.fasta] adrenomedullin precursor [HMR_022704-rand.fasta] adrenomedullin precursor [Rattus norvegicus]gi\|38197392\|gb\|AAH61775.1\| Adrenomedullin [Rattus norvegicus]gi\|1168360\|sp\|P43145\|ADML_RAT ADM precursor [Contains: Adrenomedullin (AM); Proadrenomedullin N-20 terminal peptide (ProAM-N20) (ProAM N-terminal 20 [nrdb_11152004_Chlamydomonas] Tax_Id=10116 ADM precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_012715) adrenomedullin precursor; adrenomedullin [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] ADM precursor [Contains: Adrenomedullin (AM); Proadrenomedullin N-20 terminal peptide (ProAM N-terminal 20 peptide) (ProAM-N20) (PAMP)] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] adrenomedullin precursor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] adrenomedullin, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Adrenomedullin [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] adrenomedullin [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 ADM PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] ADM precursor [Contains: Adrenomedullin (AM); Proadrenomedullin N-20 terminal peptide (ProAM-N20) (ProAM N-terminal 20 peptide) (PAMP)] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Adm ADM [rat-ipi-250309-contam.fasta] ADM OS=Rattus norvegicus GN=Adm [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	185 amino acids
Gene Ontology:
Cellular Component:	extracellular space [UNKNOWN][IDA] cytoplasm [UNKNOWN][IEA] extracellular region [IEA]
Biological Process:	response to organic substance [IEP] positive regulation of vasodilation [IMP] negative regulation of cell proliferation [IMP] negative regulation of vasoconstriction [UNKNOWN][IEA] positive regulation of cell proliferation [UNKNOWN][IEA] branching involved in embryonic placenta morphogenesis [UNKNOWN][IEA] response to wounding [IDA] response to starvation [IEP] spongiotrophoblast layer development [UNKNOWN][IEA] female pregnancy [IEP] developmental growth [UNKNOWN][IEA] aging [IEP] positive regulation of anti-apoptosis [IMP] elevation of cytosolic calcium ion concentration [IDA] heart development [UNKNOWN][IEA] response to cold [IEP] response to hypoxia [IEP] response to insulin stimulus [IEP] neural tube closure [UNKNOWN][IEA] response to glucocorticoid stimulus [IEP] neuron projection regeneration [IMP] response to lipopolysaccharide [IMP] organ regeneration [IEP] cAMP-mediated signaling [IEP]
Molecular Function:	hormone activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLVSIALML LGSLAVLGAD TARLDTSSQF RKKWNKWALS RGKRELQASS SYPTGLVDEK  60
   61 TVPTQTLGLQ DKQSTSSTPQ ASTQSTAHIR VKRYRQSMNQ GSRSTGCRFG TCTMQKLAHQ 120
  121 IYQFTDKDKD GMAPRNKISP QGYGRRRRRS LPEVLRARTV ESSQEQTHSA PASPAHQDIS 180
  181 RVSRL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ADML_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: