Protein Overview: 3BHS1_RAT

General Information:
Name(s) found:	3BHS1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|DERTH1 3beta-hydroxy-Delta5-steroid dehydrogenase multifunctional protein I - rat [NCBI NR] gi\|62644047\|ref\|XP_579404.1\| PREDICTED: hydroxysteroid dehydrogenase-1, delta<5>-3-beta (predicted) [Rattus norvegicus] [NCBI NR] gi\|59797058\|ref\|NP_001007720.3\| 3 beta-hydroxysteroid dehydrogenase 1 [Rattus norvegicus] [NCBI NR] gi\|55778611\|gb\|AAH86578.1\| Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 [Rattus norvegicus] [NCBI NR] gi\|444640\|prf\|\|1907282A hydroxysteroid dehydrogenase/isomerase [NCBI NR] ref\|XP_346638.1\| hypothetical protein XP_346637 [Rattus norvegicus] [NCBI NR] gi\|202531\|gb\|AAA63474.1\| 3-beta-hydroxysteroid dehydrogenase/delta-5-delta-4 isomerase type I [NCBI NR] gi\|149030521\|gb\|EDL85558.1\| rCG51915 [Rattus norvegicus] [NCBI NR] gi\|112769\|sp\|P22071.3\|3BHS1_RAT RecName: Full=3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; Short=3-beta-HSD I; Includes: RecName: Full=3-beta-hydroxy-Delta(5)-steroid dehydrogenase; AltName: Full=3-beta-hydroxy-5-ene steroid dehydroge [NCBI NR] 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 OS=Rattus norvegicus GN=Hsd3b1 PE=2 SV=3 [Swiss-Prot] Ensembl_locations(Chr-bp):2-188607358 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type I [hmr_yeast5_DM3-1_pombe.fasta] hypothetical protein XP_346637 [HMR_022704-rand.fasta] hypothetical protein XP_346637 [Rattus norvegicus]gi\|65962\|pir\|\|DERTH1 3beta-hydroxy-Delta5-steroid dehydrogenase multifunctional protein I - ratgi\|202531\|gb\|AAA63474.1\| 3-beta-hydroxysteroid dehydrogenase/delta-5-delta-4 isomerase type Igi\|444640\|prf\| [nrdb_11152004_Chlamydomonas] (NM_017265) hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; hydroxysteroid dehydrogenase-6, delta<5>-3-beta; Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (3-beta-HSD I) [Includes: 3-beta-hydroxy-Delta(5)-steroid dehydrogenase (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid Delta-isomerase (Delta-5-3-ketosteroid [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] rCG51915 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] hydroxysteroid dehydrogenase/isomerase [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] 3-beta-hydroxysteroid dehydrogenase/delta-5-delta-4 isomerase type I [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 HYPOTHETICAL PROTEIN XP_346637 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] hydroxysteroid dehydrogenase-1, delta<5>-3-beta [Rattus norvegicus] [nr-271106-contam.fasta] Hydroxysteroid dehydrogenase-1, delta<5>-3-beta (predicted) [Rattus norvegicus] [nr-271106-contam.fasta] 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type I (3Beta-HSD I) [Includes: 3-beta-hydroxy-delta(5)-steroid dehydrogenase (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta-isomerase (Delta-5-3-ketosteroid i [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Hsd3b1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 [rat-ipi-250309-contam.fasta] 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 OS=Rattus norvegicus GN=Hsd3b1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	373 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum membrane [IEA] mitochondrial membrane [IEA] mitochondrion [IEA] membrane [IEA] microsome [IDA] integral to membrane [IEA] endoplasmic reticulum [IEA]
Biological Process:	progesterone biosynthetic process [IDA] steroid metabolic process [IDA] oxidation reduction [IEA] steroid biosynthetic process [IEA]
Molecular Function:	3-beta-hydroxy-delta5-steroid dehydrogenase activity [IDA] steroid delta-isomerase activity [IEA] oxidoreductase activity [IEA] NAD or NADH binding [IDA] steroid binding [IPI] binding [IEA] isomerase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPGWSCLVTG AGGFVGQRII RMLVQEKELQ EVRALDKVFR PETKEEFSKL QTKAKVTMLE  60
   61 GDILDAQYLR RACQGISVVI HTAAVIDVSH VLPRQTILDV NLKGTQNILE ACVEASVPAF 120
  121 IYCSTVDVAG PNSYKKIILN GHEEEHHEST WSDAYPYSKR MAEKAVLAAN GSILKNGGTL 180
  181 HTCALRPMYI YGERSPFLSV MILAALKNKG ILNVTGKFSI ANPVYVGNVA WAHILAARGL 240
  241 RDPKKSQNVQ GQFYYISDDT PHQSYDDLNC TLSKEWGLRL DSSWSLPLPL LYWLAFLLET 300
  301 VSFLLRPFYN YRPPFNCHLV TLSNSKFTFS YKKAQRDLGY VPLVSWEEAK QKTSEWIGTL 360
  361 VEQHRETLDT KSQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.36

Protein Overview: 3BHS1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: