Protein Overview: BACE1_RAT

General Information:
Name(s) found:	BACE1_RAT [Swiss-Prot]
Description(s) found: Found 18 descriptions. SHOW ALL	Beta-secretase 1 OS=Rattus norvegicus GN=Bace1 PE=2 SV=1 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	501 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [UNKNOWN][IEA] trans-Golgi network [UNKNOWN][IEA] endosome [UNKNOWN][IDA][ISS] membrane [IEA] integral to membrane [IEA] cytoplasmic vesicle [UNKNOWN][IEA] endoplasmic reticulum [IEA] Golgi apparatus [UNKNOWN][IDA][ISS] axon [UNKNOWN][IEA] cell surface [IEA]
Biological Process:	proteolysis [UNKNOWN][IEA][ISS] beta-amyloid metabolic process [UNKNOWN][IMP][ISS]
Molecular Function:	aspartic-type endopeptidase activity [UNKNOWN][IEA][ISS] protein binding [UNKNOWN][IEA] endopeptidase activity [UNKNOWN] peptidase activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPALRWLLL WVGSGMLPAQ GTHLGIRLPL RSGLAGPPLG LRLPRETDEE PEEPGRRGSF  60
   61 VEMVDNLRGK SGQGYYVEMT VGSPPQTLNI LVDTGSSNFA VGAAPHPFLH RYYQRQLSST 120
  121 YRDLRKSVYV PYTQGKWEGE LGTDLVSIPH GPNVTVRANI AAITESDKFF INGSNWEGIL 180
  181 GLAYAEIARP DDSLEPFFDS LVKQTHIPNI FSLQLCGAGF PLNQTEALAS VGGSMIIGGI 240
  241 DHSLYTGSLW YTPIRREWYY EVIIVRVEIN GQDLKMDCKE YNYDKSIVDS GTTNLRLPKK 300
  301 VFEAAVKSIK AASSTEKFPD GFWLGEQLVC WQAGTTPWNI FPVISLYLMG EVTNQSFRIT 360
  361 ILPQQYLRPV EDVATSQDDC YKFAVSQSST GTVMGAVIME GFYVVFDRAR KRIGFAVSAC 420
  421 HVHDEFRTAA VEGPFVTADM EDCGYNIPQT DESTLMTIAY VMAAICALFM LPLCLMVCQW 480
  481 RCLRCLRHQH DDFADDISLL K

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: BACE1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: