Protein Overview: PDPK_RAT, PDPK1_RAT

General Information:
Name(s) found:	PDPK_RAT [Swiss-Prot] PDPK1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|2665356\|emb\|CAA75758.1\| PkB kinase [Rattus norvegicus] [NCBI NR] gi\|18202068\|sp\|O55173.1\|PDPK1_RAT RecName: Full=3-phosphoinositide-dependent protein kinase 1; AltName: Full=Protein kinase B kinase; Short=PkB kinase [NCBI NR] gi\|13592023\|ref\|NP_112343.1\| 3-phosphoinositide dependent protein kinase-1 [Rattus norvegicus] [NCBI NR] (O55173) 3-phosphoinositide dependent protein kinase-1 (EC 2.7.1.37) (Protein kinase B kinase) (PkB kinase) [Swiss-Prot] 3-phosphoinositide-dependent protein kinase 1 OS=Rattus norvegicus GN=Pdpk1 PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):10-11373315;10-11373315 3-phosphoinositide dependent protein kinase-1 [hmr_yeast5_DM3-1_pombe.fasta] 3-phosphoinositide dependent protein kinase-1 [HMR_022704-rand.fasta] 3-phosphoinositide dependent protein kinase-1 [Rattus norvegicus]gi\|2665356\|emb\|CAA75758.1\| PkB kinase [Rattus norvegicus]gi\|18202068\|sp\|O55173\|PDPK_RAT 3-phosphoinositide dependent protein kinase-1 (Protein kinase B kinase) (PkB kinase) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 3-phosphoinositide-dependent protein kinase 1 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 3-phosphoinositide dependent protein kinase 1 [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta] (NM_031081) 3-phosphoinositide dependent protein kinase-1 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10116 3-phosphoinositide dependent protein kinase-1 [EBI-IPI_rat_3.08_07-12-2005_origrev_con.fasta] 3-phosphoinositide-dependent protein kinase 1 (Protein kinase B kinase) (PkB kinase) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] 3-phosphoinositide dependent protein kinase-1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] PkB kinase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE-1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Pdpk1 3-phosphoinositide-dependent protein kinase 1 [rat-ipi-250309-contam.fasta] 3-phosphoinositide-dependent protein kinase 1 OS=Rattus norvegicus GN=Pdpk1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	559 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [UNKNOWN][IEA] cytosol [UNKNOWN][IDA] cytoplasmic membrane-bounded vesicle [UNKNOWN][IEA] plasma membrane [UNKNOWN][IDA]
Biological Process:	cellular response to insulin stimulus [UNKNOWN] intracellular signaling pathway [UNKNOWN] positive regulation of establishment of protein localization in plasma membrane [UNKNOWN] protein amino acid phosphorylation [IEA] focal adhesion assembly [IMP] negative regulation of protein kinase activity [UNKNOWN] hyperosmotic response [UNKNOWN][IEA] peptidyl-threonine phosphorylation [UNKNOWN] activation of protein kinase B activity [UNKNOWN]
Molecular Function:	nucleotide binding [IEA] ATP binding [IEA] protein kinase binding [IDA] protein binding [UNKNOWN] protein serine/threonine kinase activity [UNKNOWN][IEA] insulin receptor binding [IDA] transferase activity [IEA] 3-phosphoinositide-dependent protein kinase activity [UNKNOWN][IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARTTSQLYD AVPIQSSVVL CSCPSPSMVR SQTEPSSSPG IPSGVSRQGS TMDGTTAEAR  60
   61 PSTNPLQQHP AQLPPQPRKK RPEDFKFGKI LGEGSFSTVV LARELATSRE YAIKILEKRH 120
  121 IIKENKVPYV TRERDVMSRL DHPFFVKLYF TFQDDEKLYF GLSYAKNGEL LKYIRKIGSF 180
  181 DETCTRFYTA EIVSALEYLH GKGIIHRDLK PENILLNEDM HIQITDFGTA KVLSPDSKQA 240
  241 RANSFVGTAQ YVSPELLTEK SACKSSDLWA LGCIIYQLVA GLPPFRAGNE YLIFQKIIKL 300
  301 EYDFPEKFFP KARDLVEKLL VLDATKRLGC EEMEGYGPLK AHPFFESITW ENLHQQTPPK 360
  361 LTAYLPAMSE DDEDCYGNYD NLLSQFGCMQ VSSSSSSHSL CAVDASLPQR SGSNIEQYIH 420
  421 DLDTNSFELD LQFSEDEKRL LLEKQAGGNP WHQFVENNLI LKMGPVDKRK GLFARRRQLL 480
  481 LTEGPHLYYV DPVNKVLKGE IPWSQELRPE AKNFKTFFVH TPNRTYYLMD PSGNAHKWCR 540
  541 KIQEVWRQQY QSSPDAAVQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: PDPK_RAT, PDPK1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: