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Protein Overview: CD59_RAT

General Information:
Name(s) found: CD59_RAT [Swiss-Prot]
Description(s) found:
Found 21 descriptions.
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  • CD59 glycoprotein OS=Rattus norvegicus GN=Cd59 PE=1 SV=2 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 126 amino acids

    Gene Ontology:
    Cellular Component: compact myelin [IDA]
    extracellular space [IDA]
    anchored to external side of plasma membrane [UNKNOWN]
    sarcolemma [IDA]
    plasma membrane [IDA]
    cell surface [UNKNOWN]
    anchored to membrane [IEA]
    Biological Process: negative regulation of activation of membrane attack complex [UNKNOWN][IDA]
    negative regulation of complement activation [UNKNOWN]
    regulation of complement activation [NAS]
    anti-apoptosis [IMP]
    negative regulation of cytolysis [UNKNOWN]
    positive regulation of T cell proliferation [IMP]
    Molecular Function: protein binding [UNKNOWN][IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRARRGFILL LLLAVLCSTG VSLRCYNCLD PVSSCKTNST CSPNLDACLV AVSGKQVYQQ  60
   61 CWRFSDCNAK FILSRLEIAN VQYRCCQADL CNKSFEDKPN NGAISLLGKT ALLVTSVLAA 120
  121 ILKPCF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..126] PSI-BLAST 17.154902 No description for 2j8bA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • receptor activity
    		•  2.70083456904638 bayes_pls_golite062009
  • U-plasminogen activator receptor activity
    		•  2.67622889349209 bayes_pls_golite062009
  • signal transducer activity
    		•  2.48263944107373 bayes_pls_golite062009
  • molecular transducer activity
    		•  2.48263944107373 bayes_pls_golite062009
  • protein binding
    		•  2.27773193148456 bayes_pls_golite062009
  • receptor binding
    		•  1.96976025849754 bayes_pls_golite062009
  • binding
    		•  1.78861011884769 bayes_pls_golite062009
  • growth factor binding
    		•  1.43582806978958 bayes_pls_golite062009
  • cytokine binding
    		•  1.30600639196836 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  1.06543462237759 bayes_pls_golite062009
  • transforming growth factor beta binding
    		•  0.855590728274459 bayes_pls_golite062009
  • transforming growth factor beta receptor binding
    		•  0.58525546213471 bayes_pls_golite062009
  • transmembrane receptor protein serine/threonine kinase binding
    		•  0.58525546213471 bayes_pls_golite062009
  • polysaccharide binding
    		•  0.576570656707929 bayes_pls_golite062009
  • receptor serine/threonine kinase binding
    		•  0.55203098269909 bayes_pls_golite062009
  • pattern binding
    		•  0.35391370458515 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle