Protein Overview: THAS_RAT

General Information:
Name(s) found:	THAS_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|987691\|dbj\|BAA05962.1\| thromboxane synthase [Rattus norvegicus] [NCBI NR] gi\|6981634\|ref\|NP_036819.1\| thromboxane A synthase 1, platelet [Rattus norvegicus] [NCBI NR] pir\|\|S42404 thromboxane-A synthase (EC 5.3.99.5) - rat [NCBI NR] gi\|2467344\|dbj\|BAA22574.1\| thromboxane synthase [Rattus norvegicus] [NCBI NR] gi\|149065295\|gb\|EDM15371.1\| thromboxane A synthase 1 [Rattus norvegicus] [NCBI NR] gi\|1351235\|sp\|P49430.1\|THAS_RAT RecName: Full=Thromboxane-A synthase; Short=TXA synthase; Short=TXS; AltName: Full=Cytochrome P450 5A1 [NCBI NR] Thromboxane-A synthase OS=Rattus norvegicus GN=Tbxas1 PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):4-70589797 Thromboxane-A synthase [hmr_yeast5_DM3-1_pombe.fasta] thromboxane A synthase 1; ThromboxA ane synthase 1 [HMR_022704-rand.fasta] thromboxane A synthase 1 [Rattus norvegicus]gi\|1351235\|sp\|P49430\|THAS_RAT Thromboxane-A synthase (TXA synthase) (TXS)gi\|2467344\|dbj\|BAA22574.1\| thromboxane synthase [Rattus norvegicus]gi\|987691\|dbj\|BAA05962.1\| thromboxane synthase [Rattus norvegicus]g [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Thromboxane-A synthase [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_012687) thromboxA ane synthase 1 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Thromboxane-A synthase (TXA synthase) (TXS) (Cytochrome P450 5A1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] thromboxane A synthase 1, platelet [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] thromboxane A synthase 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] thromboxane synthase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 THROMBOXANE-A SYNTHASE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Tbxas1 Thromboxane-A synthase [rat-ipi-250309-contam.fasta] Thromboxane-A synthase OS=Rattus norvegicus GN=Tbxas1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	533 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] microsome [UNKNOWN][IEA] integral to membrane [IEA] cellular_component [ND]
Biological Process:	prostaglandin biosynthetic process [IEA] positive regulation of vasoconstriction [IMP] oxidation reduction [IEA] fatty acid biosynthetic process [IEA] cellular chloride ion homeostasis [IMP]
Molecular Function:	metal ion binding [IEA] electron carrier activity [IEA] monooxygenase activity [IEA] molecular_function [ND] thromboxane-A synthase activity [UNKNOWN][IEA] isomerase activity [IEA] heme binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEVLGLLKFE VSGTVVTVTL SVVLLALLKW YSTSAFSRLR KLGIRHPEPS PFVGNLMFFR  60
   61 QGFWESHLEL RERYGPLCGY YLGRRMYIVI SDPDMIKEVL VENFSNFSNR MASGLEPKLI 120
  121 ADSVLMLRDR RWEEVRGALM SAFSPEKLNE MTPLISQACE LLLSHLKHSA ASGDAFDIQR 180
  181 CYCCFTTNVV ASVAFGIEVN SQDAPEDPFV QHCQRVFAFS TPRPLLALIL SFPSIMVPLA 240
  241 RILPNKNRDE LNGFFNTLIR NVIALRDKQT AEERRGDFLQ MVLDAQRSMS SVGVEAFDMV 300
  301 TEALSSAECM GDPPQRCHPT STAKPLTVDE IAGQAFLFLI AGHEITTNTL SFITYLLATH 360
  361 PECQERLLKE VDLFMEKHPA PEYCNLQEGL PYLDMVVAET LRMYPPAFRF TREAAQDCEV 420
  421 LGQHIPAGSV LEIAVGALHH DPEHWPNPET FDPERFTAEA RLQQKPFTYL PFGAGPRSCL 480
  481 GVRLGLLVVK LTLLQVLHKF RFEACPETQV PLQLESKSAL CPKNGVYVKI VSR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: THAS_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: