Protein Overview: NEST_RAT

General Information:
Name(s) found:	NEST_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|23452508\|gb\|AAN33053.1\| nestin [Rattus norvegicus] [NCBI NR] gi\|146345465\|sp\|P21263.2\|NEST_RAT RecName: Full=Nestin [NCBI NR] Nestin OS=Rattus norvegicus GN=Nes PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):None Nestin [hmr_yeast5_DM3-1_pombe.fasta] nestin [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Nestin [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Nestin [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 NESTIN [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Nes Isoform 1 of Nestin [rat-ipi-250309-contam.fasta] Isoform 1 of Nestin OS=Rattus norvegicus GN=Nes [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	1893 amino acids
Gene Ontology:
Cellular Component:	cytoskeleton [IEA] intermediate filament cytoskeleton [UNKNOWN] cytoplasm [UNKNOWN][IEA] intermediate filament [UNKNOWN][IDA] intracellular [UNKNOWN][IEA]
Biological Process:	neuron differentiation [NAS] response to drug [IEP] nervous system development [UNKNOWN][IEA] response to nutrient levels [IEP] cell projection morphogenesis [UNKNOWN] response to ionizing radiation [IEP]
Molecular Function:	structural molecule activity [IEA] molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEGCVGEESF QMWELNRRLE AYLTRVKTLE EQNQLLSAEL GGLRAQSGDT SWRARADDEL  60
   61 ASLRILVDQR WREKLEAEVQ RDNLAEELES VAGRCQQVRL ARERTVQEAA CSRRALEAEK 120
  121 NARGWLSTQA AELERELEAL RAAHEEERAH LNAQAACAPR RPPAPPHGSP VRAPEVEDLA 180
  181 RRLGEVWRGA VRDYQERVAH MESSLGQARE RLSQAVRGAR ECRLEVQQLQ ADRDSLQERR 240
  241 EALEQRLEGR WQDRLQATDK FQLAVEALEQ EKQGLQSQIA QILEGGQQLA HLKMSLSLEV 300
  301 ATYRTLLEAE NSRLQTPGRG SQASLGFLDP KLKPNFLGIP EDQYLGSVLP ALSPTSFPSP 360
  361 LPNTLETPVT AFLKTQEFLQ ARTPTLASTP IPPISEAPCP PNAEVRAQEV PLSLLQTQAP 420
  421 EPLWAEATVP SSSAILPELE EPGGKQQGHF PDDLTSLATT LNPHHPTLEA KDGESSGSRV 480
  481 SSIFQEDEGQ IWELVEKEAD IEVKVENSSA QKTQESGLDT EETQDSQGPL QKETLKALGE 540
  541 EPLMSLKIQN YETAGKENCN SSTEGHLGTL EGPEKEKQIP LKSLEEKNVE SEKTLENGVP 600
  601 VLSELLGKED TRTEDQELMS PKGTLKRFSS LGKESQEVVR PSKEGNLESW TAFKEESQHP 660
  661 LGFPGAEDQM LERLVEKEDQ SFPRSPEEED QEACRPLQKE NQEPLGYEEA EGQILERLIE 720
  721 KESQESLRSP EEEDQEAGRS LQKGNQEPLG YEEAEGQILE RLIEKESQES LRSAEEEDQE 780
  781 ACRSLQKENQ EPLGYEEAED QILERLIEKE SQESLRSPEE EDQEAGRSLQ KENQEPLGYE 840
  841 EAEDQMLERL IEKESQESLK SPEENQRIGK PLERENQKSL RYLEENQETF VPLESRNQRP 900
  901 LRSLEVEEEE QRIVKPLEKV SQDSLGSLAE ENVQPLRYLE EDNCINKSLL EDKTHKSLGS 960
  961 LEDRNGDSII IPQESETQVS LRPPEEEDQR IVNHLEKESQ EFSRSSEEEE RVMERSLEGE1020
 1021 NHESLSSVEK EDQMVESQLE KESQDSGKSL EDESQETFGP LEKENAESLR SLAGQDQEEQ1080
 1081 KLEQETQQTL RAVGNEQMAV SPPEKVDPEL PKPLGNDQEI ARSLGKENQE SLVSLKEKGI1140
 1141 ETVKSLETEI IEPLETAEED LERRKSIDTQ EPLWSTEVAR ETVEPPEDEP PGSLGSVDEN1200
 1201 RETLTSLEKE SQELSSLGKW NVETRVEDSQ QCLQVEEGLQ EEQHQESLRE VKQELPSSGN1260
 1261 QQRWEDVVEG KAVGQEAPLA TTGVGTEDKA ELHLRGQGGE EEAAAEGELL QDIVGEAWSL1320
 1321 GSSEPKEQRV PAEALDNLEG GALEVPVAQS MPEVTERDED RAQAGEQDSI EVTLGLEAAR1380
 1381 TGLELEQEVV GLEDPRHFAR EEAIPPSLGE ESVKAKIAQG LEGPGKEPKE AGALDSGILE1440
 1441 LPKTSSEALE CQGHEESESM EGWEEEEASL ETSDHEGSDA PQPRPPETEE DEGAQAALTA1500
 1501 PGPKLLEPCS PIPILTDAHE LQPQAEGIQE AGWQPEAGSE ALERVENEPE FGLGEIPEGL1560
 1561 QDWEEGREES EADDLGETLP DSTPLGLYLR SPASPKWDLA GEQRLSPQGD AGKEDWGPAV1620
 1621 PAAQGLSGPP EEEEEQGHGS DLSSEEFEDL GTEASLLPGV PKEVADHVGQ VPPVLQPACW1680
 1681 DQGGESDGFA DEEESGEEGE EEDADEEGAE SGAQWWGSGA SGGGCKVQDI AQRGDPVQES1740
 1741 VGVSGLWDDG LRGAAANVPA LEMVSQDSAE PSGSEESESA SLEGEEGQVT DHLDAPQEVT1800
 1801 SMVPGVGDAF DIGGQSPNLD SEQVNGKMEN GLEQAEGQVV LDGDEDQELL LQGQEVGALK1860
 1861 VPLVASPVHL GPSQPLKFTL SGVDGDSWSS GED

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: NEST_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: