Protein Overview: GRIA2_RAT

General Information:
Name(s) found:	GRIA2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|3287964\|sp\|P19491.2\|GRIA2_RAT RecName: Full=Glutamate receptor 2; Short=GluR-2; AltName: Full=GluR-B; AltName: Full=GluR-K2; AltName: Full=Glutamate receptor ionotropic, AMPA 2; AltName: Full=AMPA-selective glutamate receptor 2; Flags: Precursor [NCBI NR] Glutamate receptor 2 OS=Rattus norvegicus GN=Gria2 PE=1 SV=2 [Swiss-Prot] (P19491) Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) [Swiss-Prot] Ensembl_locations(Chr-bp):None Splice isoform Flop of P19491 [hmr_yeast5_DM3-1_pombe.fasta] Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform Flop of Glutamate receptor 2 precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (AMPA-selective glutamate receptor 2) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF GLUTAMATE RECEPTOR 2 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Gria2 Isoform Flop of Glutamate receptor 2 [rat-ipi-250309-contam.fasta] Isoform Flop of Glutamate receptor 2 OS=Rattus norvegicus GN=Gria2 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	883 amino acids
Gene Ontology:
Cellular Component:	presynaptic membrane [IDA] postsynaptic density [IDA] neuronal cell body [IDA] synapse [IDA] ionotropic glutamate receptor complex [TAS] perikaryon [IDA] membrane fraction [UNKNOWN] endoplasmic reticulum membrane [IEA] growth cone [IDA] dendrite [IDA] terminal button [IDA] postsynaptic membrane [IEA] dendritic shaft [IDA] dendritic spine [IDA] endocytic vesicle membrane [UNKNOWN] alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [UNKNOWN] endoplasmic reticulum [IEA] protein complex [IDA][IPI] plasma membrane [UNKNOWN][IEA] membrane [IEA] dendrite cytoplasm [IDA] integral to membrane [IEA] cell junction [IEA] asymmetric synapse [IDA] synaptic vesicle membrane [IDA]
Biological Process:	establishment of protein localization [IMP] ion transport [IEA] positive regulation of synaptic transmission [IMP] response to lithium ion [IEP] synaptic transmission [UNKNOWN][IPI] receptor internalization [IDA] regulation of synaptic transmission, glutamatergic [IMP] regulation of receptor recycling [IMP]
Molecular Function:	ion channel activity [IEA] protein kinase binding [IPI] protein binding [IPI] PDZ domain binding [IDA][IPI] receptor activity [IDA][IEA] alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [TAS] calcium channel regulator activity [TAS] ionotropic glutamate receptor activity [UNKNOWN][IEA][TAS] extracellular-glutamate-gated ion channel activity [UNKNOWN][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQKIMHISVL LSPVLWGLIF GVSSNSIQIG GLFPRGADQE YSAFRVGMVQ FSTSEFRLTP  60
   61 HIDNLEVANS FAVTNAFCSQ FSRGVYAIFG FYDKKSVNTI TSFCGTLHVS FITPSFPTDG 120
  121 THPFVIQMRP DLKGALLSLI EYYQWDKFAY LYDSDRGLST LQAVLDSAAE KKWQVTAINV 180
  181 GNINNDKKDE TYRSLFQDLE LKKERRVILD CERDKVNDIV DQVITIGKHV KGYHYIIANL 240
  241 GFTDGDLLKI QFGGANVSGF QIVDYDDSLV SKFIERWSTL EEKEYPGAHT ATIKYTSALT 300
  301 YDAVQVMTEA FRNLRKQRIE ISRRGNAGDC LANPAVPWGQ GVEIERALKQ VQVEGLSGNI 360
  361 KFDQNGKRIN YTINIMELKT NGPRKIGYWS EVDKMVVTLT ELPSGNDTSG LENKTVVVTT 420
  421 ILESPYVMMK KNHEMLEGNE RYEGYCVDLA AEIAKHCGFK YKLTIVGDGK YGARDADTKI 480
  481 WNGMVGELVY GKADIAIAPL TITLVREEVI DFSKPFMSLG ISIMIKKPQK SKPGVFSFLD 540
  541 PLAYEIWMCI VFAYIGVSVV LFLVSRFSPY EWHTEEFEDG RETQSSESTN EFGIFNSLWF 600
  601 SLGAFMQQGC DISPRSLSGR IVGGVWWFFT LIIISSYTAN LAAFLTVERM VSPIESAEDL 660
  661 SKQTEIAYGT LDSGSTKEFF RRSKIAVFDK MWTYMRSAEP SVFVRTTAEG VARVRKSKGK 720
  721 YAYLLESTMN EYIEQRKPCD TMKVGGNLDS KGYGIATPKG SSLGNAVNLA VLKLNEQGLL 780
  781 DKLKNKWWYD KGECGSGGGD SKEKTSALSL SNVAGVFYIL VGGLGLAMLV ALIEFCYKSR 840
  841 AEAKRMKVAK NPQNINPSSS QNSQNFATYK EGYNVYGIES VKI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: GRIA2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: