Protein Overview: ABCG5_RAT

General Information:
Name(s) found:	ABCG5_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|33860121\|sp\|Q99PE7.3\|ABCG5_RAT RecName: Full=ATP-binding cassette sub-family G member 5; AltName: Full=Sterolin-1 [NCBI NR] gi\|26024223\|ref\|NP_446206.2\| ATP-binding cassette, sub-family G (WHITE), member 5 [Rattus norvegicus] [NCBI NR] gi\|24935209\|gb\|AAN64275.1\| sterolin 1 [Rattus norvegicus] [NCBI NR] gi\|22477144\|gb\|AAG53098.3\|AF312714_1 sterolin [Rattus norvegicus] [NCBI NR] gi\|149050522\|gb\|EDM02695.1\| ATP-binding cassette, sub-family G (WHITE), member 5, isoform CRA_b [Rattus norvegicus] [NCBI NR] (Q99PE7) ATP-binding cassette, sub-family G, member 5 (Sterolin-1) [Swiss-Prot] ATP-binding cassette sub-family G member 5 OS=Rattus norvegicus GN=Abcg5 PE=2 SV=3 [Swiss-Prot] Ensembl_locations(Chr-bp):6-8146764 Sterolin 1 [hmr_yeast5_DM3-1_pombe.fasta] ATP-binding cassette, sub-family G (WHITE), member 5 (sterolin 1) [HMR_022704-rand.fasta] ATP-binding cassette, sub-family G (WHITE), member 5 (sterolin 1) [Rattus norvegicus]gi\|22477144\|gb\|AAG53098.3\| sterolin [Rattus norvegicus]gi\|33860121\|sp\|Q99PE7\|ABG5_RAT ATP-binding cassette, sub-family G, member 5 (Sterolin-1)gi\|24935209\|gb\|AAN64275. [nrdb_11152004_Chlamydomonas] Tax_Id=10116 ATP-binding cassette sub-family G member 5 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 ATP-binding cassette, sub-family G, member 5 [EBI-IPI_rat_3.08_07-12-2005_origrev_con.fasta] ATP-binding cassette sub-family G member 5 (Sterolin-1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] ATP-binding cassette, sub-family G (WHITE), member 5 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] ATP-binding cassette, sub-family G (WHITE), member 5, isoform CRA_b [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] sterolin 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] sterolin [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 ATP-BINDING CASSETTE, SUB-FAMILY G, MEMBER 5 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Abcg5 ATP-binding cassette sub-family G member 5 [rat-ipi-250309-contam.fasta] ATP-binding cassette sub-family G member 5 [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] ATP-binding cassette sub-family G member 5 OS=Rattus norvegicus GN=Abcg5 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	652 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [UNKNOWN][IEA] apical part of cell [UNKNOWN] membrane [UNKNOWN][IEA] integral to membrane [IEA] plasma membrane [UNKNOWN] apical plasma membrane [UNKNOWN][IEA] ATP-binding cassette (ABC) transporter complex [TAS]
Biological Process:	negative regulation of intestinal phytosterol absorption [UNKNOWN][IEA] sterol transport [TAS] response to drug [IEP] response to nutrient [IEP] cholesterol efflux [UNKNOWN][IEA] negative regulation of intestinal cholesterol absorption [UNKNOWN][IEA] cholesterol transport [TAS] transport [IEA] regulation of intestinal cholesterol absorption [TAS] cholesterol homeostasis [UNKNOWN][IEA] excretion [UNKNOWN][IEA] response to ionizing radiation [IEP]
Molecular Function:	nucleotide binding [IEA] ATPase activity [UNKNOWN][IEA] ATP binding [UNKNOWN][IEA] protein binding [UNKNOWN][IEA] protein heterodimerization activity [UNKNOWN][IEA] cholesterol transporter activity [UNKNOWN][TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSELPFLSPE GARGPHNNRG SQSSLEEGSV TGSEARHSLG VLNVSFSVSN RVGPWWNIKS  60
   61 CQQKWDRKIL KDVSLYIESG QTMCILGSSG SGKTTLLDAI SGRLRRTGTL EGEVFVNGCE 120
  121 LRRDQFQDCV SYLLQSDVFL SSLTVRETLR YTAMLALRSS SADFYDKKVE AVLTELSLSH 180
  181 VADQMIGNYN FGGISSGERR RVSIAAQLLQ DPKVMMLDEP TTGLDCMTAN HIVLLLVELA 240
  241 RRNRIVIVTI HQPRSELFHH FDKIAILTYG ELVFCGTPEE MLGFFNNCGY PCPEHSNPFD 300
  301 FYMDLTSVDT QSREREIETY KRVQMLESAF RQSDICHKIL ENIERTRHLK TLPMVPFKTK 360
  361 NPPGMFCKLG VLLRRVTRNL MRNKQVVIMR LVQNLIMGLF LIFYLLRVQN NMLKGAVQDR 420
  421 VGLLYQLVGA TPYTGMLNAV NLFPMLRAVS DQESQDGLYQ KWQMLLAYVL HALPFSIVAT 480
  481 VIFSSVCYWT LGLYPEVARF GYFSAALLAP HLIGEFLTLV LLGMVQNPNI VNSIVALLSI 540
  541 SGLLIGSGFI RNIEEMPIPL KILGYFTFQK YCCEILVVNE FYGLNFTCGG SNTSVPNNPM 600
  601 CSMTQGIQFI EKTCPGATSR FTTNFLILYS FIPTLVILGM VVFKVRDYLI SR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ABCG5_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: