Protein Overview: HRH3_RAT

General Information:
Name(s) found:	HRH3_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|8927441\|gb\|AAF82086.1\|AF237919_1 histamine H3 receptor [Rattus norvegicus] [NCBI NR] gi\|6681588\|dbj\|BAA88766.1\| G protein-coupled receptor [Rattus norvegicus] [NCBI NR] gi\|17365993\|sp\|Q9QYN8.1\|HRH3_RAT RecName: Full=Histamine H3 receptor; Short=HH3R [NCBI NR] gi\|16758264\|ref\|NP_445958.1\| histamine receptor H3 [Rattus norvegicus] [NCBI NR] gi\|149034044\|gb\|EDL88827.1\| histamine receptor H3, isoform CRA_c [Rattus norvegicus] [NCBI NR] gi\|12831431\|gb\|AAK02069.1\| histamine H3 receptor H3L isoform [Rattus norvegicus] [NCBI NR] Histamine H3 receptor OS=Rattus norvegicus GN=Hrh3 PE=2 SV=1 [Swiss-Prot] (Q9QYN8) Histamine H3 receptor (HH3R) [Swiss-Prot] Ensembl_locations(Chr-bp):3-161862444;3-161862444 Splice isoform 1 of Q9QYN8 [hmr_yeast5_DM3-1_pombe.fasta] histamine receptor H3 [HMR_022704-rand.fasta] histamine receptor H3 [Rattus norvegicus]gi\|12831431\|gb\|AAK02069.1\| histamine H3 receptor H3L isoform [Rattus norvegicus]gi\|6681588\|dbj\|BAA88766.1\| G protein-coupled receptor [Rattus norvegicus]gi\|17365993\|sp\|Q9QYN8\|HH3R_RAT Histamine H3 receptor (HH3R [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform 1 of Histamine H3 receptor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_053506) histamine receptor H3 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Histamine H3 receptor (HH3R) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] histamine receptor H3 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] histamine receptor H3, isoform CRA_c [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] histamine H3 receptor H3L isoform [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] histamine H3 receptor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] G protein-coupled receptor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF HISTAMINE H3 RECEPTOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Hrh3 Isoform 1 of Histamine H3 receptor [rat-ipi-250309-contam.fasta] Isoform 1 of Histamine H3 receptor OS=Rattus norvegicus GN=Hrh3 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	445 amino acids
Gene Ontology:
Cellular Component:	synaptosome [IDA] myelin sheath [IDA] integral to membrane [IEA] plasma membrane [IDA]
Biological Process:	drinking behavior [IMP] negative regulation of adenylate cyclase activity [IDA] G-protein coupled receptor protein signaling pathway [IEA] signal transduction [IEA] negative regulation of gamma-aminobutyric acid secretion [IMP] negative regulation of serotonin secretion [IMP] negative regulation of glutamate secretion [IMP] regulation of norepinephrine secretion [IMP] negative regulation of blood pressure [IMP] brain development [IEP] response to organic cyclic substance [IMP] learning [IMP] memory [IMP] elevation of cytosolic calcium ion concentration [IMP] eating behavior [IMP] cognition [IMP] positive regulation of epithelial cell proliferation [IMP]
Molecular Function:	G-protein coupled receptor activity [IEA] drug binding [IDA] histamine receptor activity [IDA] receptor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERAPPDGLM NASGTLAGEA AAAGGARGFS AAWTAVLAAL MALLIVATVL GNALVMLAFV  60
   61 ADSSLRTQNN FFLLNLAISD FLVGAFCIPL YVPYVLTGRW TFGRGLCKLW LVVDYLLCAS 120
  121 SVFNIVLISY DRFLSVTRAV SYRAQQGDTR RAVRKMALVW VLAFLLYGPA ILSWEYLSGG 180
  181 SSIPEGHCYA EFFYNWYFLI TASTLEFFTP FLSVTFFNLS IYLNIQRRTR LRLDGGREAG 240
  241 PEPPPDAQPS PPPAPPSCWG CWPKGHGEAM PLHRYGVGEA GPGVEAGEAA LGGGSGGGAA 300
  301 ASPTSSSGSS SRGTERPRSL KRGSKPSASS ASLEKRMKMV SQSITQRFRL SRDKKVAKSL 360
  361 AIIVSIFGLC WAPYTLLMII RAACHGRCIP DYWYETSFWL LWANSAVNPV LYPLCHYSFR 420
  421 RAFTKLLCPQ KLKVQPHGSL EQCWK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: HRH3_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: