Protein Overview: CAN2_RAT

General Information:
Name(s) found:	CAN2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|8393038\|ref\|NP_058812.1\| calpain 2 [Rattus norvegicus] [NCBI NR] gi\|543926\|sp\|Q07009.3\|CAN2_RAT RecName: Full=Calpain-2 catalytic subunit; AltName: Full=Calpain-2 large subunit; AltName: Full=Calcium-activated neutral proteinase 2; Short=CANP 2; AltName: Full=Calpain M-type; AltName: Full=M-calpain; AltName: Full=Milli [NCBI NR] pir\|\|S38361 calpain (EC 3.4.22.17) II large chain - rat [NCBI NR] gi\|40807006\|gb\|AAH65306.1\| Calpain 2 [Rattus norvegicus] [NCBI NR] gi\|402666\|gb\|AAA16327.1\| calpain II 80 kDa subunit [NCBI NR] Calpain-2 catalytic subunit OS=Rattus norvegicus GN=Capn2 PE=1 SV=3 [Swiss-Prot] Ensembl_locations(Chr-bp):13-91047782 Calpain 2, large [catalytic] subunit precursor [hmr_yeast5_DM3-1_pombe.fasta] calpain 2 [HMR_022704-rand.fasta] calpain 2 [Rattus norvegicus]gi\|40807006\|gb\|AAH65306.1\| Calpain 2 [Rattus norvegicus]gi\|481229\|pir\|\|S38361 calpain (EC 3.4.22.17) II large chain - ratgi\|402666\|gb\|AAA16327.1\| calpain II 80 kDa subunitgi\|543926\|sp\|Q07009\|CAN2_RAT Calpain 2, large [cata [nrdb_11152004_Chlamydomonas] (NM_017116) calpain 2 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Calpain-2 catalytic subunit precursor (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M-type) (M-calpain) (Millimolar-calpain) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] calpain 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Calpain 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] calpain II 80 kDa subunit [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 CALPAIN 2, LARGE [CATALYTIC] SUBUNIT PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Capn2 Calpain-2 catalytic subunit [rat-ipi-250309-contam.fasta] Calpain-2 catalytic subunit OS=Rattus norvegicus GN=Capn2 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	700 amino acids
Gene Ontology:
Cellular Component:	insoluble fraction [IDA] soluble fraction [IDA] cytoplasm [TAS] intracellular [IEA] plasma membrane [IEA]
Biological Process:	response to hypoxia [IEP] blastocyst development [UNKNOWN][IEA] proteolysis [IDA][TAS] myoblast fusion [UNKNOWN][IEA] protein autoprocessing [IC][IDA]
Molecular Function:	protein binding [UNKNOWN][IPI] calcium ion binding [IDA] calcium-dependent cysteine-type endopeptidase activity [IDA][IPI] peptidase activity [IEA] cytoskeletal protein binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGIAMKLAK DREAAEGLGS HERAIKYLNQ DYETLRNECL EAGALFQDPS FPALPSSLGF  60
   61 KELGPYSSKT RGIEWKRPTE ICADPQFIIG GATRTDICQG ALGDCWLLAA IASLTLNEEI 120
  121 LARVVPLDQS FQENYAGIFH FQFWQYGEWV EVVVDDRLPT KDGELLFVHS AEGSEFWSAL 180
  181 LEKAYAKING CYEALSGGAT TEGFEDFTGG IAEWYELRKP PPNLFKIIQK ALEKGSLLGC 240
  241 SIDITSAADS EAVTYQKLVK GHAYSVTGAE EVESSGSLQK LIRIRNPWGQ VEWTGKWNDN 300
  301 CPSWNTVDPE VRANLTERQE DGEFWMSFSD FLRHYSRLEI CNLTPDTLTC DSYKKWKLTK 360
  361 MDGNWRRGST AGGCRNYPNT FWMNPQYLIK LEEEDEDDED GERGCTFLVG LIQKHRRRQR 420
  421 KMGEDMHTIG FGIYEVPEEL TGQTNIHLSK NFFLTTRARE RSDTFINLRE VLNRFKLPPG 480
  481 EYVLVPSTFE PHKNGDFCIR VFSEKKADYQ TVDDEIEANI EEIEANEEDI GDGFRRLFAQ 540
  541 LAGEDAEISA FELQTILRRV LAKREDIKSD GFSIETCKIM VDMLDEDGSG KLGLKEFYIL 600
  601 WTKIQKYQKI YREIDVDRSG TMNSYEMRKA LEEAGFKLPC QLHQVIVARF ADDELIIDFD 660
  661 NFVRCLVRLE ILFKIFKQLD PENTGTIQLD LISWLSFSVL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: CAN2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: