Protein Overview: HGF_RAT

General Information:
Name(s) found:	HGF_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|8393526\|ref\|NP_058713.1\| hepatocyte growth factor [Rattus norvegicus] [NCBI NR] gi\|4539554\|emb\|CAA38266.1\| hepatocyte growth factor precursor [Rattus norvegicus] [NCBI NR] gi\|220767\|dbj\|BAA14133.1\| hepatocyte growth factor prepropeptide [Rattus norvegicus] [NCBI NR] gi\|149046632\|gb\|EDL99457.1\| hepatocyte growth factor, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|149046631\|gb\|EDL99456.1\| hepatocyte growth factor, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|123117\|sp\|P17945.1\|HGF_RAT RecName: Full=Hepatocyte growth factor; AltName: Full=Scatter factor; Short=SF; AltName: Full=Hepatopoeitin-A; Contains: RecName: Full=Hepatocyte growth factor alpha chain; Contains: RecName: Full=Hepatocyte growth factor bet [NCBI NR] pir\|\|A35644 hepatocyte growth factor precursor - rat [NCBI NR] Hepatocyte growth factor OS=Rattus norvegicus GN=Hgf PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):4-14607497;4-14607497 Hepatocyte growth factor precursor [hmr_yeast5_DM3-1_pombe.fasta] hepatocyte growth factor; Hepatocyte growth factor (scatter factor) [HMR_022704-rand.fasta] hepatocyte growth factor [Rattus norvegicus]gi\|4539554\|emb\|CAA38266.1\| hepatocyte growth factor precursor [Rattus norvegicus]gi\|220767\|dbj\|BAA14133.1\| hepatocyte growth factor prepropeptide [Rattus norvegicus]gi\|111768\|pir\|\|A35644 hepatocyte growth fac [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Hepatocyte growth factor precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_017017) hepatocyte growth factor (scatter factor) [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin-A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] hepatocyte growth factor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] hepatocyte growth factor prepropeptide [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] hepatocyte growth factor, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] hepatocyte growth factor precursor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 HEPATOCYTE GROWTH FACTOR PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Hgf Hepatocyte growth factor [rat-ipi-250309-contam.fasta] hepatocyte growth factor preproprotein [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Hepatocyte growth factor OS=Rattus norvegicus GN=Hgf [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	728 amino acids
Gene Ontology:
Cellular Component:	platelet alpha granule lumen [UNKNOWN] extracellular space [IDA] extracellular region [UNKNOWN]
Biological Process:	cell proliferation [UNKNOWN][TAS] cell morphogenesis [UNKNOWN][IEA] positive regulation of cell proliferation [TAS] regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling [UNKNOWN][IEA] hepatocyte growth factor receptor signaling pathway [UNKNOWN][IEA] activation of MAPK activity [UNKNOWN][IEA] anti-apoptosis [UNKNOWN][IEA] cellular component movement [TAS] liver development [UNKNOWN][IEA] negative regulation of apoptosis [IDA] proteolysis [IEA] myoblast proliferation [UNKNOWN][IEA] organ regeneration [IEP]
Molecular Function:	growth factor activity [IMP] protein binding [UNKNOWN][IEA] catalytic activity [IEA] hepatocyte growth factor receptor binding [TAS] protein heterodimerization activity [IDA] serine-type endopeptidase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMWGTKLLPV LLLQHVLLHL LLLPVTIPYA EGQKKRRNTL HEFKKSAKTT LTKEDPLVKI  60
   61 KTKKVNSADE CANRCIRNKG FPFTCKAFVF DKSRKRCYWY PFNSMSSGVK KGFGHEFDLY 120
  121 ENKDYIRNCI IGKGGSYKGT VSITKSGIKC QPWNSMIPHE HSFLPSSYRG KDLQENYCRN 180
  181 PRGEEGGPWC FTSNPEVRYE VCDIPQCSEV ECMTCNGESY RGPMDHTESG KTCQRWDQQT 240
  241 PHRHKFLPER YPDKGFDDNY CRNPDGKPRP WCYTLDPDTP WEYCAIKMCA HSAVNETDVP 300
  301 METTECIKGQ GEGYRGTTNT IWNGIPCQRW DSQYPHKHDI TPENFKCKDL RENYCRNPDG 360
  361 AESPWCFTTD PNIRVGYCSQ IPKCDVSSGQ DCYRGNGKNY MGNLSKTRSG LTCSMWDKNM 420
  421 EDLHRHIFWE PDASKLTKNY CRNPDDDAHG PWCYTGNPLV PWDYCPISRC EGDTTPTIVN 480
  481 LDHPVISCAK TKQLRVVNGI PTQTTVGWMV SLKYRNKHIC GGSLIKESWV LTARQCFPAR 540
  541 NKDLKDYEAW LGIHDVHERG EEKRKQILNI SQLVYGPEGS DLVLLKLARP AILDNFVSTI 600
  601 DLPSYGCTIP EKTTCSIYGW GYTGLINADG LLRVAHLYIM GNEKCSQHHQ GKVTLNESEL 660
  661 CAGAEKIGSG PCEGDYGGPL ICEQHKMRMV LGVIVPGRGC AIPNRPGIFV RVAYYAKWIH 720
  721 KVILTYKL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: HGF_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: