Protein Overview: COT2_RAT

General Information:
Name(s) found:	COT2_RAT [Swiss-Prot]
Description(s) found: Found 18 descriptions. SHOW ALL	COUP transcription factor 2 OS=Rattus norvegicus GN=Nr2f2 PE=1 SV=1 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	414 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IDA][IEA]
Biological Process:	negative regulation of gene-specific transcription [UNKNOWN] limb development [UNKNOWN][IEA] anterior/posterior pattern formation [UNKNOWN][IEA] regulation of transcription, DNA-dependent [IEA][IMP] positive regulation of transcription [UNKNOWN][ISS] blood vessel morphogenesis [UNKNOWN][IEA] radial pattern formation [UNKNOWN][IEA] negative regulation of cyclin-dependent protein kinase activity [UNKNOWN] negative regulation of transcription from RNA polymerase II promoter [UNKNOWN][IEA] neuron migration [UNKNOWN][IEA] forebrain development [UNKNOWN][IEA] positive regulation of gene-specific transcription [UNKNOWN][IEA] regulation of transcription involved in lymphatic endothelial cell fate commitment [UNKNOWN][IEA] skeletal muscle tissue development [UNKNOWN][IEA] response to estradiol stimulus [IEP] negative regulation of endothelial cell proliferation [UNKNOWN] negative regulation of endothelial cell migration [UNKNOWN]
Molecular Function:	retinoic acid binding [UNKNOWN][ISS] DNA binding [UNKNOWN] transcription factor activity [IEA] zinc ion binding [IEA] protein binding [UNKNOWN][IEA] protein homodimerization activity [UNKNOWN] metal ion binding [IEA] ligand-regulated transcription factor activity [UNKNOWN][ISS] steroid hormone receptor activity [IEA] sequence-specific DNA binding [UNKNOWN][IDA] promoter binding [UNKNOWN] transcription activator activity [UNKNOWN][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAMVVSTWRD PQDEVPGSQG SQASQAPPVP GPPPGAPHTP QTPGQGGPAS TPAQTAAGSQ  60
   61 GGPGGPGSDK QQQQQHIECV VCGDKSSGKH YGQFTCEGCK SFFKRSVRRN LSYTCRANRN 120
  121 CPIDQHHRNQ CQYCRLKKCL KVGMRREAVQ RGRMPPTQPT HGQFALTNGD PLNCHSYLSG 180
  181 YISLLLRAEP YPTSRFGSQC MQPNNIMGIE NICELAARML FSAVEWARNI PFFPDLQITD 240
  241 QVALLRLTWS ELFVLNAAQC SMPLHVAPLL AAAGLHASPM SADRVVAFMD HIRIFQEQVE 300
  301 KLKALHVDSA EYSCLKAIVL FTSDACGLSD VAHVESLQEK SQCALEEYVR SQYPNQPTRF 360
  361 GKLLLRLPSL RTVSSSVIEQ LFFVRLVGKT PIETLIRDML LSGSSFNWPY MAIQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.92

Protein Overview: COT2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: