Protein Overview: TNF11_RAT

General Information:
Name(s) found:	TNF11_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|21362971\|sp\|Q9ESE2.1\|TNF11_RAT RecName: Full=Tumor necrosis factor ligand superfamily member 11; AltName: Full=Receptor activator of nuclear factor kappa B ligand; Short=RANKL; AltName: Full=TNF-related activation-induced cytokine; Short=TRANCE; AltNam [NCBI NR] gi\|16924012\|ref\|NP_476490.1\| tumor necrosis factor (ligand) superfamily, member 11 [Rattus norvegicus] [NCBI NR] gi\|10441421\|gb\|AAG17031.1\| receptor activator of NF-kB ligand [Rattus norvegicus] [NCBI NR] Tumor necrosis factor ligand superfamily member 11 OS=Rattus norvegicus GN=Tnfsf11 PE=2 SV=1 [Swiss-Prot] (Q9ESE2) Tumor necrosis factor ligand superfamily member 11 (Receptor activator of nuclear factor kappa B ligand) (RANKL) (TNF-related activation-induced cytokine) (TRANCE) (Osteoprotegerin ligand) (OPGL) (Osteoclast differentiation factor) (ODF [Swiss-Prot] Ensembl_locations(Chr-bp):15-55982625 Tumor necrosis factor ligand superfamily member 11 [hmr_yeast5_DM3-1_pombe.fasta] tumor necrosis factor (ligand) superfamily, member 11 [HMR_022704-rand.fasta] tumor necrosis factor (ligand) superfamily, member 11 [Rattus norvegicus]gi\|10441421\|gb\|AAG17031.1\| receptor activator of NF-kB ligand [Rattus norvegicus]gi\|21362971\|sp\|Q9ESE2\|TN11_RAT Tumor necrosis factor ligand superfamily member 11 (Receptor activat [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Tumor necrosis factor ligand superfamily member 11 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_057149) tumor necrosis factor (ligand) superfamily, member 11 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] tumor necrosis factor (ligand) superfamily, member 11 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tumor necrosis factor ligand superfamily member 11 (Receptor activator of nuclear factor kappa B ligand) (RANKL) (TNF-related activation-induced cytokine) (TRANCE) (Osteoprotegerin ligand) (OPGL) (Osteoclast differentiation factor) (ODF) (CD254 antigen) [ [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] receptor activator of NF-kB ligand [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 11 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Tnfsf11 Tumor necrosis factor ligand superfamily member 11 [rat-ipi-250309-contam.fasta] Tumor necrosis factor ligand superfamily member 11 OS=Rattus norvegicus GN=Tnfsf11 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	318 amino acids
Gene Ontology:
Cellular Component:	extracellular space [IEA] membrane [IEA] integral to membrane [IEA] extracellular region [IEA] plasma membrane [IEA]
Biological Process:	multicellular organismal development [IEA] response to radiation [IEP] positive regulation of I-kappaB kinase/NF-kappaB cascade [UNKNOWN][IEA] protein homooligomerization [UNKNOWN][IEA] response to stress [IEP] organ morphogenesis [UNKNOWN][IEA] osteoclast differentiation [UNKNOWN] immune response [IEA] positive regulation of osteoclast differentiation [UNKNOWN][IMP] mammary gland alveolus development [UNKNOWN][IEA] ossification [UNKNOWN][IEA] bone resorption [UNKNOWN] regulation of osteoclast differentiation [UNKNOWN] positive regulation of bone resorption [UNKNOWN][IMP] cell differentiation [IEA] mammary gland epithelial cell proliferation [UNKNOWN][IEA] positive regulation of protein kinase B signaling cascade [UNKNOWN][IEA]
Molecular Function:	protein binding [UNKNOWN][IEA] tumor necrosis factor receptor binding [IEA] receptor activity [IEA] cytokine activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRRANRDYGK YLRGSEEMGS CPGVPHEGPL HPAPSAPAPA PPPAASRFMF LALLGLGLGQ  60
   61 VVCSIALFLY FRAQMDPNRI SEDSTRCFYR ILRLRENTGL QDSTLESEDT EALPDSCRRM 120
  121 KQAFQGAVQR ELQHIVGPQR FSGVPAMMEG SWLDVARRGK PEAQPFAHLT INAADIPSGS 180
  181 HKVSLSSWYH DRGWAKISNM TLSNGKLRVN QDGFYYLYAN ICFRHHETSG SVPADYLQLM 240
  241 VYVVKTSIKI PSSHNLMKGG STKNWSGNSE FHFYSINVGG FFKLRAGEEI SVQVSNPSLL 300
  301 DPDQDATYFG AFKVQDID

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: TNF11_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: