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Any process that modulates the frequency, rate, or extent of a homeostatic process. Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity. Any process that activates or increases the frequency, rate or extent of bone remodeling. A homeostatic process involved in the maintenance of an internal steady-state within a defined tissue of an organism, including control of cellular proliferation and death and control of metabolic function. The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis. Any process that activates or increases the frequency, rate or extent of bone resorption. The process by which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products. Any process that activates or increases the frequency, rate, or extent of tissue remodeling. Any process that modulates the frequency, rate or extent of bone tissue loss (resorption). Any biological process involved in the maintenance of an internal steady-state. Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. Any process that activates or increases the frequency, rate, or extent of a homeostatic process.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: positive regulation of bone resorption
Acc: GO:0045780
Aspect: Biological Process
Desc: Any process that activates or increases the frequency, rate or extent of bone resorption.
Synonyms:
  • activation of bone resorption
  • up regulation of bone resorption
  • stimulation of bone resorption
  • upregulation of bone resorption
  • up-regulation of bone resorption
Proteins in PDR annotated with:
   This term: 9 [Search]
   Term or descendants: 9 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045780 - positive regulation of bone resorption (interactive image map)
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