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Protein Overview: AES_RAT

General Information:
Name(s) found: AES_RAT [Swiss-Prot]
Description(s) found:
Found 21 descriptions.
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  • Amino-terminal enhancer of split OS=Rattus norvegicus GN=Aes PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 197 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IDA]
    Biological Process: cellular response to extracellular stimulus [UNKNOWN]
    negative regulation of response to cytokine stimulus [UNKNOWN]
    skeletal system development [UNKNOWN]
    negative regulation of transcription [UNKNOWN]
    response to interleukin-1 [UNKNOWN]
    Wnt receptor signaling pathway [IEA]
    regulation of transcription [IEA]
    negative regulation of protein binding [UNKNOWN]
    regulation of growth [UNKNOWN]
    regulation of transcription from RNA polymerase II promoter [UNKNOWN]
    negative regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN]
    Molecular Function: protein binding [UNKNOWN]
    transcription corepressor activity [UNKNOWN]
    transcription regulator activity [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMFPQSRHSG SSHLPQQLKF TTSDSCDRIK DEFQLLQAQY HSLKLECDKL ASEKSEMQRH  60
   61 YVMYYEMSYG LNIEMHKQAE IVKRLNGICA QVLPYLSQEH QQQVLGAIER AKQVTAPELN 120
  121 SIIRQQLQAH QLSQLQALAL PLTPLPVGLQ PPSLPAVSAG TGLLSLSALG SQTHLSKEDK 180
  181 NGHDGDTHQE DDGEKSD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..197] Pfam 90.537602 No description for PF03920.6 was found. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle