Protein Overview: CASR_RAT

General Information:
Name(s) found:	CASR_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|8393053\|ref\|NP_058692.1\| calcium-sensing receptor [Rattus norvegicus] [NCBI NR] gi\|790579\|gb\|AAC52195.1\| calcium sensing receptor [NCBI NR] gi\|607816\|gb\|AAC52149.1\| kidney extracellular calcium-sensing receptor [NCBI NR] pir\|\|I59362 calcium/polyvalent cation-sensing receptor precursor - rat [NCBI NR] gi\|1586097\|prf\|\|2203270A Ca receptor [NCBI NR] gi\|149060568\|gb\|EDM11282.1\| calcium-sensing receptor, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|149060567\|gb\|EDM11281.1\| calcium-sensing receptor, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|149060565\|gb\|EDM11279.1\| calcium-sensing receptor, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|1345672\|sp\|P48442.1\|CASR_RAT RecName: Full=Extracellular calcium-sensing receptor; Short=CaSR; AltName: Full=Parathyroid Cell calcium-sensing receptor; AltName: Full=PCaR1; Flags: Precursor [NCBI NR] Extracellular calcium-sensing receptor OS=Rattus norvegicus GN=Casr PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):11-22398055;11-22398055;11-22398055 Extracellular calcium-sensing receptor precursor [hmr_yeast5_DM3-1_pombe.fasta] calcium-sensing receptor; Calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism); Calcium-sensing receptor (hypocalciuric hypercalcemia 1 severe neonatal hyperparathyroidism) [HMR_022704-rand.fasta] calcium-sensing receptor [Rattus norvegicus]gi\|2143638\|pir\|\|I59362 calcium/polyvalent cation-sensing receptor precursor - ratgi\|790579\|gb\|AAC52195.1\| calcium sensing receptorgi\|607816\|gb\|AAC52149.1\| kidney extracellular calcium-sensing receptorgi\|1345 [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Extracellular calcium-sensing receptor precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_016996) calcium-sensing receptor; Calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism) [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] calcium-sensing receptor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor) (PCaR1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] calcium-sensing receptor, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] calcium sensing receptor [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] kidney extracellular calcium-sensing receptor [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Ca receptor [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 EXTRACELLULAR CALCIUM-SENSING RECEPTOR PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Casr Extracellular calcium-sensing receptor [rat-ipi-250309-contam.fasta] calcium-sensing receptor precursor [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Extracellular calcium-sensing receptor OS=Rattus norvegicus GN=Casr [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	1079 amino acids
Gene Ontology:
Cellular Component:	integral to membrane [IEA] plasma membrane [IEA] axon terminus [IDA]
Biological Process:	detection of calcium ion [IEA] G-protein coupled receptor protein signaling pathway [IEA] ossification [IMP] signal transduction [IEA] positive regulation of ATPase activity [UNKNOWN][IEA] calcium ion transport [IMP] positive regulation of cell proliferation [IMP] JNK cascade [IMP] vasodilation [IMP] regulation of calcium ion transport [UNKNOWN][IEA] calcium-mediated signaling [IEA] cellular calcium ion homeostasis [IDA][IMP]
Molecular Function:	G-protein coupled receptor activity [IEA][IMP][TAS] receptor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASYSCCLAL LALAWHSSAY GPDQRAQKKG DIILGGLFPI HFGVAAKDQD LKSRPESVEC  60
   61 IRYNFRGFRW LQAMIFAIEE INSSPSLLPN MTLGYRIFDT CNTVSKALEA TLSFVAQNKI 120
  121 DSLNLDEFCN CSEHIPSTIA VVGATGSGVS TAVANLLGLF YIPQVSYASS SRLLSNKNQY 180
  181 KSFLRTIPND EHQATAMADI IEYFRWNWVG TIAADDDYGR PGIEKFREEA EERDICIDFS 240
  241 ELISQYSDEE EIQQVVEVIQ NSTAKVIVVF SSGPDLEPLI KEIVRRNITG RIWLASEAWA 300
  301 SSSLIAMPEY FHVVGGTIGF GLKAGQIPGF REFLQKVHPR KSVHNGFAKE FWEETFNCHL 360
  361 QEGAKGPLPV DTFVRSHEEG GNRLLNSSTA FRPLCTGDEN INSVETPYMD YEHLRISYNV 420
  421 YLAVYSIAHA LQDIYTCLPG RGLFTNGSCA DIKKVEAWQV LKHLRHLNFT NNMGEQVTFD 480
  481 ECGDLVGNYS IINWHLSPED GSIVFKEVGY YNVYAKKGER LFINEEKILW SGFSREVPFS 540
  541 NCSRDCQAGT RKGIIEGEPT CCFECVECPD GEYSGETDAS ACDKCPDDFW SNENHTSCIA 600
  601 KEIEFLAWTE PFGIALTLFA VLGIFLTAFV LGVFIKFRNT PIVKATNREL SYLLLFSLLC 660
  661 CFSSSLFFIG EPQDWTCRLR QPAFGISFVL CISCILVKTN RVLLVFEAKI PTSFHRKWWG 720
  721 LNLQFLLVFL CTFMQILICI IWLYTAPPSS YRNHELEDEI IFITCHEGSL MALGSLIGYT 780
  781 CLLAAICFFF AFKSRKLPEN FNEAKFITFS MLIFFIVWIS FIPAYASTYG KFVSAVEVIA 840
  841 ILAASFGLLA CIFFNKVYII LFKPSRNTIE EVRSSTAAHA FKVAARATLR RPNISRKRSS 900
  901 SLGGSTGSIP SSSISSKSNS EDRFPQPERQ KQQQPLSLTQ QEQQQQPLTL HPQQQQQPQQ 960
  961 PRCKQKVIFG SGTVTFSLSF DEPQKNAMAH RNSMRQNSLE AQRSNDTLGR HQALLPLQCA1020
 1021 DADSEMTIQE TGLQGPMVGD HQPEMESSDE MSPALVMSTS RSFVISGGGS SVTENVLHS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: CASR_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: