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Protein Overview: CCND1_RAT

General Information:
Name(s) found: CCND1_RAT [Swiss-Prot]
Description(s) found:
Found 19 descriptions.
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  • G1/S-specific cyclin-D1 OS=Rattus norvegicus GN=Ccnd1 PE=2 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 295 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IDA]
    cytoplasm [IDA]
    cyclin-dependent protein kinase holoenzyme complex [UNKNOWN][IEA]
    cytosol [UNKNOWN]
    intracellular [UNKNOWN][IEA]
    nucleoplasm [UNKNOWN]
    Biological Process: response to X-ray [IEP]
    response to estrogen stimulus [IEP]
    positive regulation of cell proliferation [IMP]
    lactation [UNKNOWN][IEA]
    fat cell differentiation [UNKNOWN][IEA]
    protein amino acid phosphorylation [UNKNOWN]
    re-entry into mitotic cell cycle [UNKNOWN][IEA]
    cell division [IEA]
    response to ethanol [IEP]
    response to UV-A [UNKNOWN][IEA]
    mammary gland alveolus development [UNKNOWN][IEA]
    endoplasmic reticulum unfolded protein response [UNKNOWN][IEA]
    liver development [IEP]
    G1/S transition of mitotic cell cycle [UNKNOWN][ISS]
    response to glucocorticoid stimulus [IEP]
    response to iron ion [IEP]
    response to magnesium ion [IEP]
    mammary gland epithelial cell proliferation [UNKNOWN][IEA]
    Wnt receptor signaling pathway through beta-catenin [UNKNOWN][IEA]
    regulation of cell cycle [UNKNOWN][TAS]
    response to organic substance [IEP]
    positive regulation of cyclin-dependent protein kinase activity [UNKNOWN][IEA]
    G1/S DNA damage checkpoint [UNKNOWN][ISS]
    response to vitamin E [IEP]
    response to organic cyclic substance [IEP]
    response to steroid hormone stimulus [IEP]
    response to DNA damage stimulus [UNKNOWN][ISS]
    cell cycle [UNKNOWN]
    response to corticosterone stimulus [IEP]
    negative regulation of epithelial cell differentiation [UNKNOWN][IEA]
    response to drug [IEP]
    response to calcium ion [IEP]
    positive regulation of protein amino acid phosphorylation [UNKNOWN][IEA]
    response to estradiol stimulus [IEP]
    negative regulation of Wnt receptor signaling pathway [UNKNOWN][IEA]
    organ regeneration [IEP]
    response to organic nitrogen [IDA]
    Leydig cell differentiation [IMP]
    Molecular Function: protein kinase binding [UNKNOWN][IDA]
    protein binding [UNKNOWN]
    cyclin-dependent protein kinase regulator activity [UNKNOWN][IEA]
    protein kinase activity [UNKNOWN][IEA]
    protein complex binding [IPI]
    kinase activity [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEHQLLCCEV ETIRRAYPDT NLLNDRVLRA MLKTEETCAP SVSYFKCVQR EIVPSMRKIV  60
   61 ATWMLEVCEE QKCEEEVFPL AMNYLDRFLS LEPLKKSRLQ LLGATCMFVA SKMKETIPLT 120
  121 AEKLCIYTDN SIRPEELLQM ELLLVNKLKW NLAAMTPHDF IEHFLSKMPE ADENKQIIRK 180
  181 HAQTFVALCA TDVKFISNPP SMVAAGSVVA AMQGLNLGSP NNFLSCYRTT HFLSRVIKCD 240
  241 PDCLRACQEQ IEALLESSLR QAQQNIDPKA TEEEGEVEEE AGLACTPTDV RDVDI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle