YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs. The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that decreases the frequency, rate or extent of nephron tubule epithelial cell differentiation. The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. Any process that stops, prevents or reduces the frequency, rate or extent of keratinocyte differentiation. Any process that modulates the frequency, rate or extent of epithelial cell differentiation. Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell differentiation. The process whereby a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium. Any process that stops, prevents or reduces the frequency, rate or extent of polarized epithelial cell differentiation. Any process that modulates the frequency, rate or extent of cell differentiation, the process whereby relatively unspecialized cells acquire specialized structural and functional features. Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell differentiation.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of epithelial cell differentiation
Acc: GO:0030857
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell differentiation.
Synonyms:
  • downregulation of epithelial cell differentiation
  • down regulation of epithelial cell differentiation
  • inhibition of epithelial cell differentiation
  • down-regulation of epithelial cell differentiation
Proteins in PDR annotated with:
   This term: 13 [Search]
   Term or descendants: 21 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0030857 - negative regulation of epithelial cell differentiation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle