Protein Overview: S1PR1_RAT

General Information:
Name(s) found:	S1PR1_RAT [Swiss-Prot]
Description(s) found: Found 23 descriptions. SHOW ALL	Sphingosine 1-phosphate receptor 1 OS=Rattus norvegicus GN=S1pr1 PE=1 SV=1 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	383 amino acids
Gene Ontology:
Cellular Component:	external side of plasma membrane [UNKNOWN][IEA] integral to membrane [IEA] plasma membrane [IEA]
Biological Process:	inhibition of adenylate cyclase activity by G-protein signaling pathway [UNKNOWN][IMP] G-protein coupled receptor protein signaling pathway [IMP][TAS] signal transduction [IEA] neuron differentiation [IEP] positive regulation of cell proliferation [UNKNOWN] positive regulation of positive chemotaxis [IDA] endothelial cell differentiation [IEP] brain development [UNKNOWN][IEA] positive regulation of transcription from RNA polymerase II promoter [IMP] positive regulation of smooth muscle cell proliferation [IDA] negative regulation of stress fiber assembly [IDA] angiogenesis [UNKNOWN][IEA] elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger [IMP] positive regulation of Ras GTPase activity [IDA] regulation of cell adhesion [UNKNOWN][IEA] transmission of nerve impulse [IEP] positive regulation of cell migration [IDA]
Molecular Function:	G-protein coupled receptor activity [IMP][TAS] lysosphingolipid and lysophosphatidic acid receptor activity [IEA] receptor activity [IEA] sphingolipid binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSSTSIPVV KALRSQVSDY GNYDIIVRHY NYTGKLNIGV EKDHGIKLTS VVFILICCLI  60
   61 ILENIFVLLT IWKTKKFHRP MYYFIGNLAL SDLLAGVAYT ANLLLSGATT YKLTPAQWFL 120
  121 REGSMFVALS ASVFSLLAIA IERYITMLKM KLHNGSNSSR SFLLISACWV ISLILGGLPI 180
  181 MGWNCISSLS SCSTVLPLYH KHYILFCTTV FTLLLLSIVI LYCRIYSLVR TRSRRLTFRK 240
  241 NISKASRSSE KSLALLKTVI IVLSVFIACW APLFILLLLD VGCKAKTCDI LYKAEYFLVL 300
  301 AVLNSGTNPI IYTLTNKEMR RAFIRIISCC KCPNGDSAGK FKRPIIPGME FSRSKSDNSS 360
  361 HPQKDDGDNP ETIMSSGNVN SSS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: S1PR1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: