Protein Overview: THB_RAT

General Information:
Name(s) found:	THB_RAT [Swiss-Prot]
Description(s) found: Found 10 descriptions. SHOW ALL	Thyroid hormone receptor beta OS=Rattus norvegicus GN=Thrb PE=1 SV=2 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	461 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA][TAS]
Biological Process:	female courtship behavior [UNKNOWN][IEA] positive regulation of cell proliferation [IMP] regulation of heart contraction [UNKNOWN][IEA] regulation of transcription, DNA-dependent [IEA] embryonic organ development [IEP] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN][IEA] negative regulation of female receptivity [UNKNOWN][IEA] regulation of transcription from RNA polymerase II promoter [UNKNOWN] organ morphogenesis [UNKNOWN][IEA] positive regulation of ossification [IDA] regulation of cholesterol metabolic process [IMP] negative regulation of transcription from RNA polymerase II promoter [UNKNOWN][IEA] sensory perception of sound [UNKNOWN][IEA] negative regulation of transcription [UNKNOWN][IEA] positive regulation of chondrocyte differentiation [IDA] regulation of lipid metabolic process [IDA] regulation of triglyceride metabolic process [IMP]
Molecular Function:	thyroid hormone receptor activity [IDA][IEA] transcription factor activity [IEA] zinc ion binding [IEA] protein binding [UNKNOWN][IEA] protein homodimerization activity [IDA] ligand-dependent nuclear receptor activity [TAS] metal ion binding [IEA] double-stranded DNA binding [IDA] steroid hormone receptor activity [IEA] sequence-specific DNA binding [IEA] transcription repressor activity [UNKNOWN][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTPNSMTENR LPAWDKQKPH PDRGQDWKLV GMSEACLHRK SHVERRGALK NEQTSSHLIQ  60
   61 ATWASSIFHL DPDDVNDQSV SSAQTFQTEE KKCKGYIPSY LDKDELCVVC GDKATGYHYR 120
  121 CITCEGCKGF FRRTIQKSLH PSYSCKYEGK CIIDKVTRNQ CQECRFKKCI YVGMATDLVL 180
  181 DDSKRLAKRK LIEENREKRR REELQKSIGH KPEPTDEEWE LIKTVTEAHV ATNAQGSHWK 240
  241 QKRKFLPEDI GQAPIVNAPE GGQVDLEAFS HFTKIITPAI TRVVDFAKKL PMFCELPCED 300
  301 QIILLKGCCM EIMSLRAAVR YDPDSETLTL NGEMAVTRGQ LKNGGLGVVS DAIFDLGMSL 360
  361 SSFNLDDTEV ALLQAVLLMS SDRPGLACVE RIEKYQDSFL LAFEHYINYR KHHVTHFWPK 420
  421 LLMKVTDLRM IGACHASRFL HMKVECPTEL FPPLFLEVFE D

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: THB_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: