Protein Overview: 5HT2C_RAT

General Information:
Name(s) found:	5HT2C_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|A32605 serotonin receptor 1C - rat [NCBI NR] gi\|207066\|gb\|AAA42177.1\| serotonin 1c receptor [NCBI NR] gi\|17298688\|ref\|NP_036897.2\| 5-hydroxytryptamine (serotonin) receptor 2C [Rattus norvegicus] [NCBI NR] gi\|112817\|sp\|P08909.1\|5HT2C_RAT RecName: Full=5-hydroxytryptamine receptor 2C; Short=5-HTR2C; Short=5-HT-2C; Short=5-HT2C; AltName: Full=5HT-1C; AltName: Full=Serotonin receptor 2C [NCBI NR] 5-hydroxytryptamine receptor 2C OS=Rattus norvegicus GN=Htr2c PE=1 SV=1 [Swiss-Prot] (P08909) 5-hydroxytryptamine 2C receptor (5-HT-2C) (Serotonin receptor 2C) (5HT-1C) [Swiss-Prot] Ensembl_locations(Chr-bp):7-139852755 5-hydroxytryptamine 2C receptor [hmr_yeast5_DM3-1_pombe.fasta] 5-hydroxytryptamine (serotonin) receptor 2C [HMR_022704-rand.fasta] 5-hydroxytryptamine (serotonin) receptor 2C [Rattus norvegicus]gi\|92748\|pir\|\|A32605 serotonin receptor 1C - ratgi\|207066\|gb\|AAA42177.1\| serotonin 1c receptorgi\|112817\|sp\|P08909\|5H2C_RAT 5-hydroxytryptamine 2C receptor (5-HT-2C) (Serotonin receptor 2C) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 5-hydroxytryptamine 2C receptor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_012765) 5-hydroxytryptamine (serotonin) receptor 2C [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] 5-hydroxytryptamine (serotonin) receptor 2C [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] 5-hydroxytryptamine receptor 2C (5-HTR2C) (5-HT-2C) (5-HT2C) (5HT-1C) (Serotonin receptor 2C) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] serotonin 1c receptor [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] 5-hydroxytryptamine 2C receptor (5-HT-2C) (Serotonin receptor 2C) (5-HT2C) (5-HTR2C) (5HT-1C) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Htr2c 5-hydroxytryptamine receptor 2C [rat-ipi-250309-contam.fasta] 5-hydroxytryptamine receptor 2C OS=Rattus norvegicus GN=Htr2c [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	460 amino acids
Gene Ontology:
Cellular Component:	external side of plasma membrane [IDA] integral to membrane [IEA] plasma membrane [IMP]
Biological Process:	positive regulation of acetylcholine secretion [IMP] negative regulation of locomotion [IMP] G-protein coupled receptor protein signaling pathway [IEA] behavioral response to nicotine [IMP] signal transduction [IEA] G-protein signaling, coupled to cyclic nucleotide second messenger [TAS] positive regulation of gamma-aminobutyric acid secretion [IMP] positive regulation of vasoconstriction [IMP] feeding behavior [IMP] negative regulation of dopamine metabolic process [IMP] activation of phospholipase C activity by serotonin receptor signaling pathway [IDA] inositol phosphate-mediated signaling [IDA] response to drug [IMP] activation of phospholipase D activity by G-protein coupled receptor protein signaling pathway [IMP] organ regeneration [IEP] regulation of sensory perception of pain [IMP]
Molecular Function:	serotonin binding [UNKNOWN] G-protein coupled receptor activity [IEA] protein binding [UNKNOWN][IPI] receptor activity [IEA] serotonin receptor activity [UNKNOWN][IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVNLGNAVRS LLMHLIGLLV WQFDISISPV AAIVTDTFNS SDGGRLFQFP DGVQNWPALS  60
   61 IVVIIIMTIG GNILVIMAVS MEKKLHNATN YFLMSLAIAD MLVGLLVMPL SLLAILYDYV 120
  121 WPLPRYLCPV WISLDVLFST ASIMHLCAIS LDRYVAIRNP IEHSRFNSRT KAIMKIAIVW 180
  181 AISIGVSVPI PVIGLRDESK VFVNNTTCVL NDPNFVLIGS FVAFFIPLTI MVITYFLTIY 240
  241 VLRRQTLMLL RGHTEEELAN MSLNFLNCCC KKNGGEEENA PNPNPDQKPR RKKKEKRPRG 300
  301 TMQAINNEKK ASKVLGIVFF VFLIMWCPFF ITNILSVLCG KACNQKLMEK LLNVFVWIGY 360
  361 VCSGINPLVY TLFNKIYRRA FSKYLRCDYK PDKKPPVRQI PRVAATALSG RELNVNIYRH 420
  421 TNERVARKAN DPEPGIEMQV ENLELPVNPS NVVSERISSV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: 5HT2C_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: