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Protein Overview: KLK1_MOUSE

General Information:
Name(s) found: KLK1_MOUSE [Swiss-Prot]
Description(s) found:
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  • gi|520591|dbj|BAA01257.1| tissue kallikrein [Mus musculus] [NCBI NR]
  • gi|31980868|ref|NP_034769.4| kallikrein 1 [Mus musculus] [NCBI NR]
  • gi|31657181|gb|AAH53697.1| Kallikrein 1 [Mus musculus] [NCBI NR]
  • gi|20379615|gb|AAH27736.1| Kallikrein 1 [Mus musculus] [NCBI NR]
  • gi|17433705|sp|P15947.3|KLK1_MOUSE RecName: Full=Kallikrein-1; AltName: Full=Tissue kallikrein-6; Short=mGK-6; AltName: Full=Glandular kallikrein K1; AltName: Full=Renal kallikrein; AltName: Full=KAL-B; Flags: Precursor [NCBI NR]
  • gi|14789646|gb|AAH10754.1| Kallikrein 1 [Mus musculus] [NCBI NR]
  • gi|12832144|dbj|BAB21982.1| unnamed protein product [Mus musculus] [NCBI NR]
  • (P15947) Glandular kallikrein K6 precursor (EC 3.4.21.35) (Tissue kallikrein-6) (mGK-6) (Renal kallikrein) (KAL-B) [Swiss-Prot]
  • Kallikrein-1 OS=Mus musculus GN=Klk1 PE=1 SV=3 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):7-32852655 Glandular kallikrein K6 precursor [hmr_yeast5_DM3-1_pombe.fasta]
  • kallikrein 6; kallikrein renal/pancreas/salivary [HMR_022704-rand.fasta]
  • Glandular kallikrein K6 precursor [ipi.MOUSE.v3.06.fasta]
  • kallikrein 6 [Mus musculus]gi|14789646|gb|AAH10754.1| Kallikrein 6 [Mus musculus]gi|31657181|gb|AAH53697.1| Kallikrein 6 [Mus musculus]gi|20379615|gb|AAH27736.1| Kallikrein 6 [Mus musculus]gi|520591|dbj|BAA01257.1| tissue kallikrein [Mus musculus]gi| [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10090 Glandular kallikrein K6 precursor [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta]
  • kallikrein 6 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • Glandular kallikrein K1 precursor (Tissue kallikrein-6) (mGK-6) (Renal kallikrein) (KAL-B) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • kallikrein 1 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Kallikrein 1 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • tissue kallikrein [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10090 GLANDULAR KALLIKREIN K6 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Klk1 Kallikrein-1 [mouse-ipi-250309-contam.fasta]
  • kallikrein 1 precursor [Mus musculus] [NCBI-RefSeq_mouse_na_09-14-2009_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Klk1 Glandular kallikrein K1 precursor [ipi.MOUSE_jw_12may08.contam.fasta]
  • Tax_Id=10090 Gene_Symbol=Klk1 Glandular kallikrein K1 precursor ENSMUSG00000063903 IPI00323869 [IPIxENS.MOUSE_plus_REVERSE.fasta]
  • kallikrein-1 precursor [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta]
  • IPI:IPI00323869.1|SWISS-PROT:P15947|ENSEMBL:ENSMUSP00000074659|REFSEQ:NP_034769 Tax_Id=10090 Gene_Symbol=Klk1 Kallikrein-1 [ipi.MOUSE.fasta.20090209]
  • Kallikrein-1 OS=Mus musculus GN=Klk1 [011711_HMR.fasta]
  • sp|P15947|KLK1_MOUSE Kallikrein-1 OS=Mus musculus GN=Klk1 PE=1 SV=3 [uniprot.sptr.mouse.20130102]
  • Isoform of P15947, Kallikrein 1 OS=Mus musculus GN=Klk1 PE=1 SV=1 [MOUSE.fasta.20160308]
    • Organism: Mus musculus
    Length: 261 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRFLILFLAL SLGGIDAAPP VQSRIVGGFN CEKNSQPWQV AVYRFTKYQC GGILLNANWV  60
   61 LTAAHCHNDK YQVWLGKNNF LEDEPSAQHR LVSKAIPHPD FNMSLLNEHT PQPEDDYSND 120
  121 LMLLRLKKPA DITDVVKPID LPTEEPKLGS TCLASGWGSI TPVKYEYPDE LQCVNLKLLP 180
  181 NEDCAKAHIE KVTDDMLCAG DMDGGKDTCA GDSGGPLICD GVLQGITSWG PSPCGKPNVP 240
  241 GIYTRVLNFN TWIRETMAEN D

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..261] PSI-BLAST 72.30103 7S NGF protease subunits

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidase activity
    		•  5.91209560688646 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  5.52773635813967 bayes_pls_golite062009
  • serine hydrolase activity
    		•  5.5105092190926 bayes_pls_golite062009
  • serine-type peptidase activity
    		•  5.49703869306079 bayes_pls_golite062009
  • serine-type endopeptidase activity
    		•  5.39623690248556 bayes_pls_golite062009
  • endopeptidase activity
    		•  5.32070018460528 bayes_pls_golite062009
  • hydrolase activity
    		•  4.40346950809697 bayes_pls_golite062009
  • fucose binding
    		•  3.5000591397073 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  2.01328116441763 bayes_pls_golite062009
  • calcium-dependent protein binding
    		•  1.96509840108953 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.73928761064649 bayes_pls_golite062009
  • receptor activity
    		•  1.63666837038605 bayes_pls_golite062009
  • DNA binding
    		•  1.61536775064425 bayes_pls_golite062009
  • heparin binding
    		•  1.48285358055737 bayes_pls_golite062009
  • thrombospondin receptor activity
    		•  1.44312413043539 bayes_pls_golite062009
  • catalytic activity
    		•  1.40927913545237 bayes_pls_golite062009
  • polysaccharide binding
    		•  1.34665327732001 bayes_pls_golite062009
  • binding
    		•  1.30738106455622 bayes_pls_golite062009
  • protein binding
    		•  1.30414885212044 bayes_pls_golite062009
  • signal transducer activity
    		•  1.30072283618388 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.30072283618388 bayes_pls_golite062009
  • serine-type aminopeptidase activity
    		•  0.964413112640311 bayes_pls_golite062009
  • growth factor activity
    		•  0.848900101748605 bayes_pls_golite062009
  • receptor binding
    		•  0.79054390509229 bayes_pls_golite062009
  • calcium ion binding
    		•  0.753095272942721 bayes_pls_golite062009
  • peptide binding
    		•  0.348186768259137 bayes_pls_golite062009
  • sodium channel regulator activity
    		•  0.30724450617383 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle