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Protein Overview: MYD88_MOUSE

General Information:
Name(s) found: MYD88_MOUSE [Swiss-Prot]
Description(s) found:
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  • gi|74220746|dbj|BAE31345.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|74198869|dbj|BAE30658.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|6754772|ref|NP_034981.1| myeloid differentiation primary response gene 88 [Mus musculus] [NCBI NR]
  • gi|37589152|gb|AAH58787.1| Myeloid differentiation primary response gene 88 [Mus musculus] [NCBI NR]
  • gi|2459632|gb|AAB83958.1| myleoid differentiation primary response marker [Mus musculus] [NCBI NR]
  • gi|20141515|sp|P22366.3|MYD88_MOUSE RecName: Full=Myeloid differentiation primary response protein MyD88 [NCBI NR]
  • gi|148677279|gb|EDL09226.1| myeloid differentiation primary response gene 88, isoform CRA_c [Mus musculus] [NCBI NR]
  • gi|13542775|gb|AAH05591.1| Myeloid differentiation primary response gene 88 [Mus musculus] [NCBI NR]
  • Myeloid differentiation primary response protein MyD88 OS=Mus musculus GN=Myd88 PE=1 SV=3 [Swiss-Prot]
  • (P22366) Myeloid differentiation primary response protein MyD88 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):9-119440673 Myeloid differentiation primary response protein MyD88 [hmr_yeast5_DM3-1_pombe.fasta]
  • myeloid differentiation primary response gene 88 [HMR_022704-rand.fasta]
  • Myeloid differentiation primary response protein MyD88 [ipi.MOUSE.v3.06.fasta]
  • myeloid differentiation primary response gene 88 [Mus musculus]gi|13542775|gb|AAH05591.1| Myeloid differentiation primary response gene 88 [Mus musculus]gi|37589152|gb|AAH58787.1| Myeloid differentiation primary response gene 88 [Mus musculus]gi|201415 [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10090 Myeloid differentiation primary response protein MyD88 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta]
  • (NM_010851) myeloid differentiation primary response gene 88 [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • myeloid differentiation primary response gene 88 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • myeloid differentiation primary response gene 88, isoform CRA_c [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Myeloid differentiation primary response gene 88 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • myleoid differentiation primary response marker [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10090 MYELOID DIFFERENTIATION PRIMARY RESPONSE PROTEIN MYD88 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Myd88 Myeloid differentiation primary response protein MyD88 [mouse-ipi-250309-contam.fasta]
  • Tax_Id=10090 Gene_Symbol=Myd88 Myeloid differentiation primary response protein MyD88 ENSMUSG00000032508 IPI00127375 IPI00754505 [IPIxENS.MOUSE_plus_REVERSE.fasta]
  • myeloid differentiation primary response protein MyD88 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta]
  • IPI:IPI00127375.1|SWISS-PROT:P22366|TREMBL:Q0PM15;Q0PM16;Q3TIB3;Q3U6W5;Q3U7M4;Q3UDG9;Q8C1X0|ENSEMBL:ENSMUSP00000035092|REFSEQ:NP_034981|VEGA:OTTMUSP00000018013 Tax_Id=10090 Gene_Symbol=Myd88 Myeloid differentiation primary response protein MyD88 [ipi.MOUSE.fasta.20090209]
  • Isoform 1 of Myeloid differentiation primary response protein MyD88 OS=Mus musculus GN=Myd88 [011711_HMR.fasta]
  • Tax_Id=10090 Gene_Symbol=Myd88 Isoform 1 of Myeloid differentiation primary response protein MyD88 [EBI-IPI_mouse_2_08-18-2011_reversed.fasta]
  • sp|P22366|MYD88_MOUSE Myeloid differentiation primary response protein MyD88 OS=Mus musculus GN=Myd88 PE=1 SV=3 [uniprot.sptr.mouse.20130102]
  • tr|Q3U7M4|Q3U7M4_MOUSE Myeloid differentiation primary response gene 88, isoform CRA_c OS=Mus musculus GN=Myd88 PE=2 SV=1 [uniprot.sptr.mouse.20130102]
  • Myeloid differentiation primary response gene 88, isoform CRA_c OS=Mus musculus GN=Myd88 PE=2 SV=1 [mouse-uniprot-290313-contam.fasta]
  • Myeloid differentiation primary response protein MyD88 OS=Mus musculus GN=Myd88 PE=2 SV=1 [mouse-uniprot-oct2014-contam.fasta]
    • Organism: Mus musculus
    Length: 296 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAGDPRVGS GSLDSFMFSI PLVALNVGVR RRLSLFLNPR TPVAADWTLL AEEMGFEYLE  60
   61 IRELETRPDP TRSLLDAWQG RSGASVGRLL ELLALLDRED ILKELKSRIE EDCQKYLGKQ 120
  121 QNQESEKPLQ VARVESSVPQ TKELGGITTL DDPLGQTPEL FDAFICYCPN DIEFVQEMIR 180
  181 QLEQTDYRLK LCVSDRDVLP GTCVWSIASE LIEKRCRRMV VVVSDDYLQS KECDFQTKFA 240
  241 LSLSPGVQQK RLIPIKYKAM KKDFPSILRF ITICDYTNPC TKSWFWTRLA KALSLP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..140] PSI-BLAST 16.30103 Solution Structure of the pelle Death Domain
    2 View Details [141..296] PSI-BLAST 33.0 Toll-like receptor 2, TLR2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein binding
    		•  3.50518632995622 bayes_pls_golite062009
  • binding
    		•  2.81925838257497 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  1.66783807193588 bayes_pls_golite062009
  • receptor activity
    		•  1.49139108045528 bayes_pls_golite062009
  • enzyme binding
    		•  0.78444772609923 bayes_pls_golite062009
  • tumor necrosis factor binding
    		•  0.732234543123958 bayes_pls_golite062009
  • death receptor activity
    		•  0.627802739213643 bayes_pls_golite062009
  • apoptotic protease activator activity
    		•  0.487782160925381 bayes_pls_golite062009
  • tumor necrosis factor receptor activity
    		•  0.428938788578756 bayes_pls_golite062009
  • Pyrin domain binding
    		•  0.307516801321075 bayes_pls_golite062009
  • identical protein binding
    		•  0.206123549797411 bayes_pls_golite062009
  • signal transducer activity
    		•  0.201651915574531 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.201651915574531 bayes_pls_golite062009
  • protein domain specific binding
    		•  0.151782936408674 bayes_pls_golite062009
  • death domain binding
    		•  0.119918387246423 bayes_pls_golite062009
  • cytokine binding
    		•  0.0519010687665362 bayes_pls_golite062009
  • peptidase activator activity
    		•  0.0460645022887266 bayes_pls_golite062009
  • catalytic activity
    		•  0.043183590691418 bayes_pls_golite062009
    2
    Term Confidence Notes
  • double-stranded RNA binding
    		•  4.32086914489227 bayes_pls_golite062009
  • siRNA binding
    		•  3.8837709376582 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.46815521682665 bayes_pls_golite062009
  • binding
    		•  2.31499720771829 bayes_pls_golite062009
  • protein binding
    		•  2.10005190551596 bayes_pls_golite062009
  • receptor activity
    		•  1.91178122133017 bayes_pls_golite062009
    		• 1.86047705807897 bayes_pls_golite062009
  • lipopolysaccharide binding
    		•  1.79927076993237 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  1.68133457503491 bayes_pls_golite062009
  • DNA binding
    		•  1.10666978727222 bayes_pls_golite062009
  • RNA binding
    		•  0.964496567264848 bayes_pls_golite062009
  • signal transducer activity
    		•  0.574489626172021 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.574489626172021 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  0.0787292540642052 bayes_pls_golite062009
  • growth factor activity
    		•  0.0066769104515047 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.56

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle