Protein Overview: PRKN2_MOUSE

General Information:
Name(s) found:	PRKN2_MOUSE [Swiss-Prot]
Description(s) found: Found 26 descriptions. SHOW ALL	E3 ubiquitin-protein ligase parkin OS=Mus musculus GN=Park2 PE=1 SV=1 [Swiss-Prot]
Organism:	Mus musculus
Length:	464 amino acids
Gene Ontology:
Cellular Component:	postsynaptic density [UNKNOWN] synaptic vesicle [UNKNOWN] endoplasmic reticulum [UNKNOWN] Golgi membrane [UNKNOWN] synapse [IEA] protein complex [IDA] cell projection [IEA] neuron projection [IDA] plasma membrane [IEA] intracellular [UNKNOWN] nucleus [IEA] postsynaptic membrane [IEA] cytoplasm [IEA] membrane raft [UNKNOWN] membrane [IEA] cell junction [IEA] cytoplasmic vesicle [UNKNOWN]
Biological Process:	norepinephrine metabolic process [IMP] protein metabolic process [IMP] regulation of neurotransmitter secretion [IMP] [NOT]dopamine metabolic process [IMP] adult locomotory behavior [IMP] [NOT]learning [IMP] response to unfolded protein [UNKNOWN] synaptic transmission, dopaminergic [IMP] [NOT]locomotory behavior [IMP] dopamine uptake [IMP] startle response [IMP] regulation of synaptic transmission [IMP] synaptic transmission, glutamatergic [IMP]
Molecular Function:	ubiquitin-protein ligase activity [IEA] zinc ion binding [IEA] protein binding [IPI] metal ion binding [IEA] acid-amino acid ligase activity [IEA] protein complex binding [UNKNOWN] ligase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIVFVRFNSS YGFPVEVDSD TSILQLKEVV AKRQGVPADQ LRVIFAGKEL PNHLTVQNCD  60
   61 LEQQSIVHIV QRPRRRSHET NASGGDEPQS TSEGSIWESR SLTRVDLSSH TLPVDSVGLA 120
  121 VILDTDSKRD SEAARGPVKP TYNSFFIYCK GPCHKVQPGK LRVQCGTCKQ ATLTLAQGPS 180
  181 CWDDVLIPNR MSGECQSPDC PGTRAEFFFK CGAHPTSDKD TSVALNLITS NRRSIPCIAC 240
  241 TDVRSPVLVF QCNHRHVICL DCFHLYCVTR LNDRQFVHDA QLGYSLPCVA GCPNSLIKEL 300
  301 HHFRILGEEQ YTRYQQYGAE ECVLQMGGVL CPRPGCGAGL LPEQGQRKVT CEGGNGLGCG 360
  361 FVFCRDCKEA YHEGDCDSLL EPSGATSQAY RVDKRAAEQA RWEEASKETI KKTTKPCPRC 420
  421 NVPIEKNGGC MHMKCPQPQC KLEWCWNCGC EWNRACMGDH WFDV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: PRKN2_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: