Protein Overview: NEP_MOUSE

General Information:
Name(s) found:	NEP_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|51338732\|sp\|Q61391.3\|NEP_MOUSE RecName: Full=Neprilysin; AltName: Full=Neutral endopeptidase 24.11; Short=Neutral endopeptidase; Short=NEP; AltName: Full=Enkephalinase; AltName: Full=Atriopeptidase; AltName: CD_antigen=CD10 [NCBI NR] gi\|31543255\|ref\|NP_032630.2\| membrane metallo endopeptidase [Mus musculus] [NCBI NR] gi\|26329497\|dbj\|BAC28487.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|26327333\|dbj\|BAC27410.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|21707622\|gb\|AAH34092.1\| Mme protein [Mus musculus] [NCBI NR] gi\|148703443\|gb\|EDL35390.1\| membrane metallo endopeptidase, isoform CRA_b [Mus musculus] [NCBI NR] Neprilysin OS=Mus musculus GN=Mme PE=1 SV=3 [Swiss-Prot] Ensembl_locations(Chr-bp):3-63609570 Membrane metallo endopeptidase [hmr_yeast5_DM3-1_pombe.fasta] membrane metallo endopeptidase; neprilysin; common acute lymphoblastic leukemia antigen [HMR_022704-rand.fasta] Mme protein [Mus musculus]gi\|31543255\|ref\|NP_032630.2\| membrane metallo endopeptidase [Mus musculus]gi\|51338732\|sp\|Q61391\|NEP_MOUSE Neprilysin (Neutral endopeptidase) (NEP) (Enkephalinase) (Neutral endopeptidase 24.11) (CD10)gi\|26329497\|dbj\|BAC28487.1\| [nrdb_11152004_Chlamydomonas] membrane metallo endopeptidase [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Neprilysin (Neutral endopeptidase 24.11) (Neutral endopeptidase) (NEP) (Enkephalinase) (Atriopeptidase) (CD10 antigen) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] membrane metallo endopeptidase, isoform CRA_b [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Mme protein [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Mme Neprilysin [mouse-ipi-250309-contam.fasta] Neprilysin (Neutral endopeptidase) (NEP) (Enkephalinase) (Neutral endopeptidase 24.11) (Atriopeptidase) (CD10 antigen) [nr-271106-contam.fasta] Tax_Id=10090 Gene_Symbol=Mme Neprilysin ENSMUSG00000027820 IPI00461861 [IPIxENS.MOUSE_plus_REVERSE.fasta] neprilysin [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00461861.5\|SWISS-PROT:Q61391\|TREMBL:Q8BNU9\|ENSEMBL:ENSMUSP00000029400;ENSMUSP00000103521\|REFSEQ:NP_032630 Tax_Id=10090 Gene_Symbol=Mme Neprilysin [ipi.MOUSE.fasta.20090209] Neprilysin OS=Mus musculus GN=Mme [011711_HMR.fasta] sp\|Q61391\|NEP_MOUSE Neprilysin OS=Mus musculus GN=Mme PE=1 SV=3 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	750 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [UNKNOWN] membrane [IDA] integral to membrane [IEA] plasma membrane [UNKNOWN]
Biological Process:	peptide metabolic process [UNKNOWN] proteolysis [UNKNOWN]
Molecular Function:	metal ion binding [IEA] peptide binding [UNKNOWN] peptidase activity [IDA] metalloendopeptidase activity [IEA] hydrolase activity [IEA] metallopeptidase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRSESQMDI TDINAPKPKK KQRWTPLEIS LSVLVLLLTI IAVTMIALYA TYDDGICKSS  60
   61 DCIKSAARLI QNMDASVEPC TDFFKYACGG WLKRNVIPET SSRYSNFDIL RDELEVILKD 120
  121 VLQEPKTEDI VAVQKAKTLY RSCINESAID SRGGQPLLKL LPDIYGWPVA SDNWDQTYGT 180
  181 SWTAEKSIAQ LNSKYGKKVL INFFVGTDDK NSTQHIIHFD QPRLGLPSRD YYECTGIYKE 240
  241 ACTAYVDFMI SVARLIRQEQ SLPIDENQLS LEMNKVMELE KEIANATTKP EDRNDPMLLY 300
  301 NKMTLAKLQN NFSLEVNGKS FSWSNFTNEI MSTVNINIQN EEEVVVYAPE YLTKLKPILT 360
  361 KYSPRDLQNL MSWRFIMDLV SSLSRNYKES RNAFRKALYG TTSETATWRR CANYVNGNME 420
  421 NAVGRLYVEA AFAGESKHVV EDLIAQIREV FIQTLDDLTW MDAETKKKAE EKALAIKERI 480
  481 GYPDDIISNE NKLNNEYLEL NYREDEYFEN IIQNLKFSQS KQLKKLREKV DKDEWISGAA 540
  541 VVNAFYSSGR NQIVFPAGIL QPPFFSAQQS NSLNYGGIGM VIGHEITHGF DDNGRNFNKD 600
  601 GDLVDWWTQQ SANNFKDQSQ CMVYQYGNFS WDLAGGQHLN GINTLGENIA DNGGIGQAYR 660
  661 AYQNYVKKNG EEKLLPGLDL NHKQLFFLNF AQVWCGTYRP EYAVNSIKTD VHSPGNFRII 720
  721 GTLQNSAEFA DAFHCRKNSY MNPERKCRVW

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: NEP_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: