Protein Overview: PDE1B_MOUSE

General Information:
Name(s) found:	PDE1B_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6679243\|ref\|NP_032826.1\| phosphodiesterase 1B [Mus musculus] [NCBI NR] pir\|\|A46378 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17) 1B, calmodulin-dependent, 63K splice form - mouse [NCBI NR] gi\|200270\|gb\|AAA39902.1\| calmodulin-dependent phosphodiesterase [NCBI NR] gi\|1705943\|sp\|Q01065.2\|PDE1B_MOUSE RecName: Full=Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B; Short=Cam-PDE 1B; AltName: Full=63 kDa Cam-PDE [NCBI NR] gi\|148671966\|gb\|EDL03913.1\| phosphodiesterase 1B, Ca2+-calmodulin dependent, isoform CRA_c [Mus musculus] [NCBI NR] Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B OS=Mus musculus GN=Pde1b PE=1 SV=2 [Swiss-Prot] (Q01065) Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (EC 3.1.4.17) (Cam-PDE 1B) (63 kDa Cam-PDE) [Swiss-Prot] Ensembl_locations(Chr-bp):15-103960171 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B [hmr_yeast5_DM3-1_pombe.fasta] phosphodiesterase 1B, Ca2+-calmodulin dependent; phosphodiesterase 1B1, Ca2+-calmodulin dependent, 63 kDa; phosphodiesterase 1B, Ca2+-calmodulin dependent, 63 kDa [HMR_022704-rand.fasta] Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B [ipi.MOUSE.v3.06.fasta] phosphodiesterase 1B, Ca2+-calmodulin dependent [Mus musculus]gi\|1705943\|sp\|Q01065\|CN1B_MOUSE Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Cam-PDE 1B) (63 kDa Cam-PDE)gi\|423407\|pir\|\|A46378 3',5'-cyclic-nucleotide phosphodie [nrdb_11152004_Chlamydomonas] Tax_Id=10090 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] (NM_008800) phosphodiesterase 1B, Ca2+-calmodulin dependent, 63 kDa; phosphodiesterase 1B1, Ca2+-calmodulin dependent, 63 kDa [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] phosphodiesterase 1B, Ca2+-calmodulin dependent [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Cam-PDE 1B) (63 kDa Cam-PDE) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] phosphodiesterase 1B, Ca2+-calmodulin dependent, isoform CRA_c [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] calmodulin-dependent phosphodiesterase [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 CALCIUM/CALMODULIN-DEPENDENT 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1B [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Pde1b Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B [mouse-ipi-250309-contam.fasta] phosphodiesterase 1B [Mus musculus] [NCBI-RefSeq_mouse_na_09-14-2009_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Pde1b Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B ENSMUSG00000022489 IPI00118900 [IPIxENS.MOUSE_plus_REVERSE.fasta] calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00118900.1\|SWISS-PROT:Q01065\|TREMBL:Q6PDS5;Q9DBS6\|ENSEMBL:ENSMUSP00000023132\|REFSEQ:NP_032826 Tax_Id=10090 Gene_Symbol=Pde1b Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B [ipi.MOUSE.fasta.20090209] Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B OS=Mus musculus GN=Pde1b [011711_HMR.fasta] sp\|Q01065\|PDE1B_MOUSE Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B OS=Mus musculus GN=Pde1b PE=1 SV=2 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	535 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IEA] neuronal cell body [UNKNOWN]
Biological Process:	locomotory behavior [IMP] cGMP catabolic process [UNKNOWN] signal transduction [IMP] cAMP catabolic process [UNKNOWN] visual learning [IMP]
Molecular Function:	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity [UNKNOWN] calmodulin binding [IEA] metal ion binding [IEA] catalytic activity [IEA] calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity [UNKNOWN] cyclic-nucleotide phosphodiesterase activity [UNKNOWN] 3',5'-cyclic-AMP phosphodiesterase activity [UNKNOWN] hydrolase activity [IEA] 3',5'-cyclic-nucleotide phosphodiesterase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELSPRSPPE MLESDCPSPL ELKSAPSKKM WIKLRSLLRY MVKQLENGEV NIEELKKNLE  60
   61 YTASLLEAVY IDETRQILDT EDELRELRSD AVPSEVRDWL ASTFTQQTRA KGRRAEEKPK 120
  121 FRSIVHAVQA GIFVERMFRR TYTSVGPTYS TAVHNCLKNL DLWCFDVFSL NRAADDHALR 180
  181 TIVFELLTRH SLISRFKIPT VFLMSFLEAL ETGYGKYKNP YHNQIHAADV TQTVHCFLLR 240
  241 TGMVHCLSEI EVLAIIFAAA IHDYEHTGTT NSFHIQTKSE CAILYNDRSV LENHHISSVF 300
  301 RMMQDDEMNI FINLTKDEFA ELRALVIEMV LATDMSCHFQ QVKTMKTALQ QLERIDKSKA 360
  361 LSLLLHAADI SHPTKQWSVH SRWTKALMEE FFRQGDKEAE LGLPFSPLCD RTSTLVAQSQ 420
  421 IGFIDFIVEP TFSVLTDVAE KSVQPLADDD SKPKSQPSFQ WRQPSLDVDV GDPNPDVVSF 480
  481 RATWTKYIQE NKQKWKERAA SGITNQMSID ELSPCEEEAP SSPAEDEHNQ NGNLD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: PDE1B_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: