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Protein Overview: ATOH1_MOUSE

General Information:
Name(s) found: ATOH1_MOUSE [Swiss-Prot]
Description(s) found:
Found 28 descriptions.
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  • Protein atonal homolog 1 OS=Mus musculus GN=Atoh1 PE=2 SV=1 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 351 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    Biological Process: auditory receptor cell fate determination [IDA]
    transcription [IEA]
    neuron differentiation [IMP]
    positive regulation of auditory receptor cell differentiation [IDA]
    axon guidance [IMP]
    brain development [IMP]
    regulation of neuron differentiation [IDA]
    regulation of transcription [IEA]
    positive regulation of transcription from RNA polymerase II promoter [IDA][IMP]
    auditory receptor cell fate specification [IMP]
    neuron migration [IMP]
    auditory receptor cell differentiation [IDA][IMP]
    apoptosis [IMP]
    inner ear morphogenesis [IMP]
    cell differentiation [IMP]
    Molecular Function: DNA binding [IDA]
    chromatin DNA binding [IDA]
    protein binding [IPI]
    transcription regulator activity [IEA]
    sequence-specific DNA binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRLLHAEEW AEVKELGDHH RHPQPHHVPP LTPQPPATLQ ARDLPVYPAE LSLLDSTDPR  60
   61 AWLTPTLQGL CTARAAQYLL HSPELGASEA AAPRDEADSQ GELVRRSGCG GLSKSPGPVK 120
  121 VREQLCKLKG GVVVDELGCS RQRAPSSKQV NGVQKQRRLA ANARERRRMH GLNHAFDQLR 180
  181 NVIPSFNNDK KLSKYETLQM AQIYINALSE LLQTPNVGEQ PPPPTASCKN DHHHLRTASS 240
  241 YEGGAGASAV AGAQPAPGGG PRPTPPGPCR TRFSGPASSG GYSVQLDALH FPAFEDRALT 300
  301 AMMAQKDLSP SLPGGILQPV QEDNSKTSPR SHRSDGEFSP HSHYSDSDEA S

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle