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Protein Overview: IPKA_MOUSE

General Information:
Name(s) found: IPKA_MOUSE [Swiss-Prot]
Description(s) found:
Found 29 descriptions.
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  • cAMP-dependent protein kinase inhibitor alpha OS=Mus musculus GN=Pkia PE=1 SV=2 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 76 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    soluble fraction [IDA]
    cytoplasm [IDA]
    Biological Process: negative regulation of transcription from RNA polymerase II promoter [IDA]
    negative regulation of protein import into nucleus [IDA]
    negative regulation of catalytic activity [IDA]
    negative regulation of protein kinase activity [IDA]
    regulation of G2/M transition of mitotic cell cycle [IMP]
    Molecular Function: protein kinase inhibitor activity [IEA]
    kinase activity [IEA]
    cAMP-dependent protein kinase inhibitor activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDVETTYAD FIASGRTGRR NAIHDILVSS ASGNSNELAL KLAGLDINKT EGEDDGQRSS  60
   61 TEQSGEAQGE AAKSES

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..76] Pfam 47.657577 No description for PF02827.7 was found. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle