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A process by which a protein is transported to, or maintained in, a location within the nucleus. Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells. The directed movement of substances into the nucleus. The process of targeting specific proteins to particular membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif. Any process that stops, prevents or reduces the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of a protein into, out of, within or between cells by means of some external agent such as a transporter or pore. The directed movement of a protein from the cytoplasm to the nucleus. The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. The directed movement of molecules between the nucleus and the cytoplasm. Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells. Any process that stops, prevents or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus. The directed movement of proteins into a cell or organelle. Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells. Any process that modulates the frequency, rate or extent of movement of proteins from the cytoplasm to the nucleus. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus. Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of protein import into nucleus
Acc: GO:0042308
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus.
Synonyms:
  • downregulation of protein import into nucleus
  • inhibition of protein import into nucleus
  • negative regulation of protein-nucleus import
  • negative regulation of protein import into cell nucleus
  • down regulation of protein import into nucleus
  • down-regulation of protein import into nucleus
  • negative regulation of protein transport from cytoplasm to nucleus
Proteins in PDR annotated with:
   This term: 8 [Search]
   Term or descendants: 29 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0042308 - negative regulation of protein import into nucleus (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle