Protein Overview: SOX8_MOUSE

General Information:
Name(s) found:	SOX8_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|7025337\|gb\|AAF35837.1\|AF191325_1 SRY-related protein SOX 8 [Mus musculus] [NCBI NR] gi\|55249580\|gb\|AAH85619.1\| SRY-box containing gene 8 [Mus musculus] [NCBI NR] gi\|33563276\|ref\|NP_035577.1\| SRY-box containing gene 8 [Mus musculus] [NCBI NR] gi\|26343663\|dbj\|BAC35488.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|26328277\|dbj\|BAC27879.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|148690483\|gb\|EDL22430.1\| SRY-box containing gene 8, isoform CRA_b [Mus musculus] [NCBI NR] gi\|10720403\|sp\|Q04886.2\|SOX8_MOUSE RecName: Full=Transcription factor SOX-8 [NCBI NR] Transcription factor SOX-8 OS=Mus musculus GN=Sox8 PE=2 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):17-24259304 Transcription factor SOX-8 [hmr_yeast5_DM3-1_pombe.fasta] SRY-box containing gene 8 [HMR_022704-rand.fasta] Transcription factor SOX-8 [ipi.MOUSE.v3.06.fasta] SRY-box containing gene 8 [Mus musculus]gi\|33563276\|ref\|NP_035577.1\| SRY-box containing gene 8 [Mus musculus]gi\|7025337\|gb\|AAF35837.1\| SRY-related protein SOX 8 [Mus musculus]gi\|10720403\|sp\|Q04886\|SOX8_MOUSE Transcription factor SOX-8gi\|26343663\|dbj\|B [nrdb_11152004_Chlamydomonas] Tax_Id=10090 Transcription factor SOX-8 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] SRY-box containing gene 8 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] SRY-box containing gene 8, isoform CRA_b [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] SRY-related protein SOX 8 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 TRANSCRIPTION FACTOR SOX-8 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Sox8 Transcription factor SOX-8 [mouse-ipi-250309-contam.fasta] Tax_Id=10090 Gene_Symbol=Sox8 Transcription factor SOX-8 ENSMUSG00000024176 IPI00111141 [IPIxENS.MOUSE_plus_REVERSE.fasta] transcription factor SOX-8 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00111141.1\|SWISS-PROT:Q04886\|TREMBL:Q543C3;Q80V52;Q8CBZ8;Q8CCB9\|ENSEMBL:ENSMUSP00000025003\|REFSEQ:NP_035577 Tax_Id=10090 Gene_Symbol=Sox8 Transcription factor SOX-8 [ipi.MOUSE.fasta.20090209] Transcription factor SOX-8 OS=Mus musculus GN=Sox8 [011711_HMR.fasta] sp\|Q04886\|SOX8_MOUSE Transcription factor SOX-8 OS=Mus musculus GN=Sox8 PE=2 SV=2 [uniprot.sptr.mouse.20130102] tr\|Q543C3\|Q543C3_MOUSE SRY-box containing gene 8, isoform CRA_b OS=Mus musculus GN=Sox8 PE=2 SV=1 [uniprot.sptr.mouse.20130102] SRY-box containing gene 8, isoform CRA_b OS=Mus musculus GN=Sox8 PE=2 SV=1 [mouse-uniprot-290313-contam.fasta] Putative uncharacterized protein OS=Mus musculus GN=Sox8 PE=2 SV=1 [UniProt_mouse_01-27-2011_reversed.fasta] Isoform of Q04886, SRY-box containing gene 8, isoform CRA_b OS=Mus musculus GN=Sox8 PE=1 SV=1 [MOUSE.fasta.20160308]
Organism:	Mus musculus
Length:	464 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] cytoplasm [IMP]
Biological Process:	positive regulation of osteoblast proliferation [IMP] oligodendrocyte differentiation [IMP] transcription [IEA] male gonad development [IGI] spermatogenesis [IGI][IMP] peripheral nervous system development [IGI] Sertoli cell development [IGI] cell maturation [IGI][IMP] fat cell differentiation [IMP] regulation of transcription [IEA] positive regulation of transcription from RNA polymerase II promoter [IDA] adipose tissue development [IMP] regulation of hormone levels [IMP] in utero embryonic development [IGI] positive regulation of transcription, DNA-dependent [IMP] negative regulation of myoblast differentiation [IDA] positive regulation of gene expression [IGI] negative regulation of transcription [IDA] cell fate commitment [IGI] osteoblast differentiation [IMP]
Molecular Function:	DNA binding [IDA] transcription factor activity [IDA][IMP] protein binding [IPI] sequence-specific DNA binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLDMSEARAQ PPCSPSGTAS SMSHVEDSDS DAPPSPAGSE GLGRAGGGGR GDTAEAADER  60
   61 FPACIRDAVS QVLKGYDWSL VPMPVRGGGG GTLKAKPHVK RPMNAFMVWA QAARRKLADQ 120
  121 YPHLHNAELS KTLGKLWRLL SESEKRPFVE EAERLRVQHK KDHPDYKYQP RRRKSVKTGR 180
  181 SDSDSGTELG HHPGGPMYKA DAVLGEAHHH SDHHTGQTHG PPTPPTTPKT DLHQASNGSK 240
  241 QELRLEGRRL VDSGRQNIDF SNVDISELSS EVISNMDTFD VHEFDQYLPL NGHSALPTEP 300
  301 SQATASGSYG GASYSHSGAT GIGASPVWAH KGAPSASASP TEAGPLRPQI KTEQLSPSHY 360
  361 NDQSHGSPGR ADYGSYSAQA SVTTAASATA ASSFASAQCD YTDLQASNYY SPYPGYPPSL 420
  421 YQYPYFHSSR RPYASPLLNG LSMPPAHSPS SNWDQPVYTT LTRP

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: SOX8_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: