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Protein Overview: SOX8_MOUSE

General Information:
Name(s) found: SOX8_MOUSE [Swiss-Prot]
Description(s) found:
Found 28 descriptions.
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  • Transcription factor SOX-8 OS=Mus musculus GN=Sox8 PE=2 SV=2 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 464 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    cytoplasm [IMP]
    Biological Process: positive regulation of osteoblast proliferation [IMP]
    oligodendrocyte differentiation [IMP]
    transcription [IEA]
    male gonad development [IGI]
    spermatogenesis [IGI][IMP]
    peripheral nervous system development [IGI]
    Sertoli cell development [IGI]
    cell maturation [IGI][IMP]
    fat cell differentiation [IMP]
    regulation of transcription [IEA]
    positive regulation of transcription from RNA polymerase II promoter [IDA]
    adipose tissue development [IMP]
    regulation of hormone levels [IMP]
    in utero embryonic development [IGI]
    positive regulation of transcription, DNA-dependent [IMP]
    negative regulation of myoblast differentiation [IDA]
    positive regulation of gene expression [IGI]
    negative regulation of transcription [IDA]
    cell fate commitment [IGI]
    osteoblast differentiation [IMP]
    Molecular Function: DNA binding [IDA]
    transcription factor activity [IDA][IMP]
    protein binding [IPI]
    sequence-specific DNA binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLDMSEARAQ PPCSPSGTAS SMSHVEDSDS DAPPSPAGSE GLGRAGGGGR GDTAEAADER  60
   61 FPACIRDAVS QVLKGYDWSL VPMPVRGGGG GTLKAKPHVK RPMNAFMVWA QAARRKLADQ 120
  121 YPHLHNAELS KTLGKLWRLL SESEKRPFVE EAERLRVQHK KDHPDYKYQP RRRKSVKTGR 180
  181 SDSDSGTELG HHPGGPMYKA DAVLGEAHHH SDHHTGQTHG PPTPPTTPKT DLHQASNGSK 240
  241 QELRLEGRRL VDSGRQNIDF SNVDISELSS EVISNMDTFD VHEFDQYLPL NGHSALPTEP 300
  301 SQATASGSYG GASYSHSGAT GIGASPVWAH KGAPSASASP TEAGPLRPQI KTEQLSPSHY 360
  361 NDQSHGSPGR ADYGSYSAQA SVTTAASATA ASSFASAQCD YTDLQASNYY SPYPGYPPSL 420
  421 YQYPYFHSSR RPYASPLLNG LSMPPAHSPS SNWDQPVYTT LTRP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle