Protein Overview: ISL2_MOUSE

General Information:
Name(s) found:	ISL2_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|20978508\|sp\|Q9CXV0.1\|ISL2_MOUSE RecName: Full=Insulin gene enhancer protein ISL-2; Short=Islet-2 [NCBI NR] gi\|13386228\|ref\|NP_081673.1\| insulin related protein 2 (islet 2) [Mus musculus] [NCBI NR] gi\|12851555\|dbj\|BAB29088.1\| unnamed protein product [Mus musculus] [NCBI NR] Insulin gene enhancer protein ISL-2 OS=Mus musculus GN=Isl2 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):9-55699918 Insulin gene enhancer protein ISL-2 [hmr_yeast5_DM3-1_pombe.fasta] insulin related protein 2 (islet 2); islet 2; insulin gene enhancer protein ISL-2 [HMR_022704-rand.fasta] Insulin gene enhancer protein ISL-2 [ipi.MOUSE.v3.06.fasta] insulin related protein 2 (islet 2) [Mus musculus]gi\|20978508\|sp\|Q9CXV0\|ISL2_MOUSE Insulin gene enhancer protein ISL-2 (Islet-2)gi\|12851555\|dbj\|BAB29088.1\| unnamed protein product [Mus musculus] [nrdb_11152004_Chlamydomonas] Tax_Id=10090 Insulin gene enhancer protein ISL-2 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] (NM_027397) RIKEN cDNA 3110001N10 [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] insulin related protein 2 (islet 2) [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Insulin gene enhancer protein ISL-2 (Islet-2) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 INSULIN GENE ENHANCER PROTEIN ISL-2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Isl2 Insulin gene enhancer protein ISL-2 [mouse-ipi-250309-contam.fasta] Tax_Id=10090 Gene_Symbol=Isl2 Insulin gene enhancer protein ISL-2 ENSMUSG00000032318 IPI00110854 IPI00785312 [IPIxENS.MOUSE_plus_REVERSE.fasta] IPI:IPI00110854.1\|SWISS-PROT:Q9CXV0\|ENSEMBL:ENSMUSP00000034869\|REFSEQ:NP_081673 Tax_Id=10090 Gene_Symbol=Isl2 Insulin gene enhancer protein ISL-2 [ipi.MOUSE.fasta.20090209] Insulin gene enhancer protein ISL-2 OS=Mus musculus GN=Isl2 [011711_HMR.fasta] Insulin gene enhancer protein ISL-2 OS=Mus musculus GN=Isl2 PE=2 SV=1 [UniProt_mouse_sprotvarsplic_11-08-2010_reversed.fasta]
Organism:	Mus musculus
Length:	359 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA] intracellular [IDA]
Biological Process:	retinal ganglion cell axon guidance [IMP] multicellular organismal development [IEA] neuron fate commitment [IGI][IMP] negative regulation of neuron differentiation [IGI][IMP] regulation of transcription, DNA-dependent [IEA] visceral motor neuron differentiation [IGI][IMP] regulation of transcription [IEA]
Molecular Function:	DNA binding [IEA] transcription factor activity [IEA] zinc ion binding [IEA] transcription regulator activity [IEA] metal ion binding [IEA] sequence-specific DNA binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVDIIFHYPF LGAMGDHSKK KPGTAMCVGC GSQIHDQFIL RVSPDLEWHA ACLKCAECSQ  60
   61 YLDETCTCFV RDGKTYCKRD YVRLFGIKCA QCQVGFSSSD LVMRARDSVY HIECFRCSVC 120
  121 SRQLLPGDEF SLREHELLCR ADHGLLLERA AAGSPRTPGP LPGARGLHLP DAGSGRQPSL 180
  181 RTHVDKQAEK TTRVRTVLNE KQLHTLRTCY AANPRPDALM KEQLVEMTGL SPRVIRVWFQ 240
  241 NKRCKDKKKS ILMKQLQQQQ HSDKASFQGL TGTPLVAGSP IGHENAVQGS AVEVQTYQPP 300
  301 WKALSEFALQ SDLDQPAFQQ LVSFSESGSL GNSSGSDVTS LSSQLPDTPN SMVPSPVET

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: ISL2_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: