Protein Overview: HME1_MOUSE

General Information:
Name(s) found:	HME1_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|8480961\|gb\|AAA03660.2\| engrailed protein [Mus musculus] [NCBI NR] gi\|7106305\|ref\|NP_034263.1\| engrailed 1 [Mus musculus] [NCBI NR] pir\|\|A48423 engrailed homeodomain-containing protein En-1 - mouse [NCBI NR] gi\|462292\|sp\|P09065.2\|HME1_MOUSE RecName: Full=Homeobox protein engrailed-1; Short=Mo-En-1 [NCBI NR] gi\|148707846\|gb\|EDL39793.1\| engrailed 1 [Mus musculus] [NCBI NR] Homeobox protein engrailed-1 OS=Mus musculus GN=En1 PE=2 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):1-120797517 Homeobox protein engrailed-1 [hmr_yeast5_DM3-1_pombe.fasta] engrailed 1; engrailed-1 [HMR_022704-rand.fasta] Homeobox protein engrailed-1 [ipi.MOUSE.v3.06.fasta] engrailed 1 [Mus musculus]gi\|8480961\|gb\|AAA03660.2\| engrailed protein [Mus musculus]gi\|462292\|sp\|P09065\|HME1_MOUSE Homeobox protein engrailed-1 (Mo-En-1)gi\|477223\|pir\|\|A48423 engrailed homeodomain-containing protein En-1 - mouse [nrdb_11152004_Chlamydomonas] Tax_Id=10090 Homeobox protein engrailed-1 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] (NM_010133) engrailed 1 [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] engrailed 1 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Homeobox protein engrailed-1 (Mo-En-1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] engrailed protein [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 HOMEOBOX PROTEIN ENGRAILED-1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=En1 Homeobox protein engrailed-1 [mouse-ipi-250309-contam.fasta] IPI:IPI00132510.1\|SWISS-PROT:P09065 Tax_Id=10090 Gene_Symbol=En1 Homeobox protein engrailed-1 [ipi.MOUSE.fasta.20090209] Homeobox protein engrailed-1 OS=Mus musculus GN=En1 [011711_HMR.fasta]
Organism:	Mus musculus
Length:	401 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA]
Biological Process:	multicellular organismal development [IEA] neuron differentiation [IGI] midbrain-hindbrain boundary development [IMP] regulation of transcription, DNA-dependent [IEA] neuron development [IGI] regulation of transcription [IEA] positive regulation of transcription from RNA polymerase II promoter [IDA] proximal/distal pattern formation [IMP] dorsal/ventral pattern formation [IMP] embryonic limb morphogenesis [IGI][IMP] midbrain development [IGI] hindbrain development [IGI] pigmentation [IMP] embryonic forelimb morphogenesis [IGI]
Molecular Function:	DNA binding [IEA] transcription factor activity [IEA] transcription regulator activity [IEA] sequence-specific DNA binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEQQPEPKS QRDSGLGAVA AAAPSGLSLS LSPGASGSSG SDGDSVPVSP QPAPPSPPAA  60
   61 PCLPPLAHHP HLPPHPPPPP PPPPPPPQHL AAPAHQPQPA AQLHRTTNFF IDNILRPDFG 120
  121 CKKEQPLPQL LVASAAAGGG AAAGGGSRVE RDRGQTGAGR DPVHSLGTRA SGAASLLCAP 180
  181 DANCGPPDGS QPATAVGAGA SKAGNPAAAA AAAAAAAAAA VAAAAAAASK PSDSGGGSGG 240
  241 NAGSPGAQGA KFPEHNPAIL LMGSANGGPV VKTDSQQPLV WPAWVYCTRY SDRPSSGPRT 300
  301 RKLKKKKNEK EDKRPRTAFT AEQLQRLKAE FQANRYITEQ RRQTLAQELS LNESQIKIWF 360
  361 QNKRAKIKKA TGIKNGLALH LMAQGLYNHS TTTVQDKDES E

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: HME1_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: