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Protein Overview: MBL1_MOUSE

General Information:
Name(s) found: MBL1_MOUSE [Swiss-Prot]
Description(s) found:
Found 33 descriptions.
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  • Mannose-binding protein A OS=Mus musculus GN=Mbl1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 239 amino acids

    Gene Ontology:
    Cellular Component: extracellular space [UNKNOWN][IDA]
    extracellular region [IEA]
    Biological Process: killing by host of symbiont cells [IGI]
    negative regulation of growth of symbiont in host [IGI]
    innate immune response [IEA]
    complement activation, classical pathway [IEA]
    complement activation, lectin pathway [UNKNOWN][IDA][IGI]
    positive regulation of phagocytosis [IGI]
    defense response to Gram-positive bacterium [IGI]
    Molecular Function: mannose binding [UNKNOWN]
    protein homodimerization activity [UNKNOWN]
    sugar binding [IEA]
    calcium ion binding [UNKNOWN]
    calcium-dependent protein binding [UNKNOWN]
    binding [IEA]
    polysaccharide binding [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLLPLLPVL LCVVSVSSSG SQTCEDTLKT CSVIACGRDG RDGPKGEKGE PGQGLRGLQG  60
   61 PPGKLGPPGS VGSPGSPGPK GQKGDHGDNR AIEEKLANME AEIRILKSKL QLTNKLHAFS 120
  121 MGKKSGKKLF VTNHEKMPFS KVKSLCTELQ GTVAIPRNAE ENKAIQEVAT GIAFLGITDE 180
  181 ATEGQFMYVT GGRLTYSNWK KDEPNNHGSG EDCVIILDNG LWNDISCQAS FKAVCEFPA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..112] PSI-BLAST 4.522879 No description for 1y0fB was found.
    2 View Details [113..239] PSI-BLAST 24.522879 Mannose-binding protein A, lectin domain; Mannose-binding protein A


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle