General Information: |
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Name(s) found: |
TGFR2_MOUSE
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Mus musculus |
Length: | 592 amino acids |
Gene Ontology: |
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Cellular Component: |
integral to plasma membrane
[UNKNOWN]
caveola [UNKNOWN] cytoplasm [UNKNOWN] membrane [IEA] external side of plasma membrane [IDA] integral to membrane [IEA] cytosol [UNKNOWN] receptor complex [IEA] cell surface [UNKNOWN] |
Biological Process: |
trachea formation
[IMP]
negative regulation of cardiac muscle cell proliferation [UNKNOWN] lung lobe morphogenesis [IMP] mammary gland morphogenesis [IMP] embryonic hemopoiesis [IMP] negative regulation of cell proliferation [UNKNOWN] palate development [IMP] transforming growth factor beta receptor signaling pathway [UNKNOWN] auxin biosynthetic process [IEA] transmembrane receptor protein serine/threonine kinase signaling pathway [IEA] vasculogenesis [IMP] protein amino acid phosphorylation [TAS] lung morphogenesis [IMP] positive regulation of B cell tolerance induction [IMP] positive regulation of smooth muscle cell proliferation [UNKNOWN] heart development [IMP] patterning of blood vessels [IMP] in utero embryonic development [IMP] myeloid dendritic cell differentiation [IMP] activation of protein kinase activity [IDA] lung development [IMP] response to cholesterol [IDA] common-partner SMAD protein phosphorylation [UNKNOWN] smoothened signaling pathway [IMP] embryonic cranial skeleton morphogenesis [IMP] trachea morphogenesis [IMP] positive regulation of mesenchymal cell proliferation [IMP] brain development [IMP] bronchus development [IMP] receptor-mediated endocytosis [UNKNOWN] bronchus morphogenesis [IMP] regulation of cell proliferation [IMP] positive regulation of tolerance induction to self antigen [IMP] organ morphogenesis [UNKNOWN] gastrulation [IMP] positive regulation of T cell tolerance induction [IMP] positive regulation of NK T cell differentiation [IMP] |
Molecular Function: |
protein kinase activity
[IEA]
protein serine/threonine kinase activity [IEA] receptor activity [IEA] transforming growth factor beta receptor activity, type II [UNKNOWN] nucleotide binding [IEA] ATP binding [IEA] receptor signaling protein serine/threonine kinase activity [IEA] protein binding [IPI] SMAD binding [IDA] metal ion binding [IEA] mitogen-activated protein kinase kinase kinase binding [UNKNOWN] transferase activity [IEA] kinase activity [IEA] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MGRGLLRGLW PLHIVLWTRI ASTIPPHVPK SDVEMEAQKD ASIHLSCNRT IHPLKHFNSD 60 61 VMASDNGGAV KLPQLCKFCD VRLSTCDNQK SCMSNCSITA ICEKPHEVCV AVWRKNDKNI 120 121 TLETVCHDPK LTYHGFTLED AASPKCVMKE KKRAGETFFM CACNMEECND YIIFSEEYTT 180 181 SSPDLLLVII QVTGVSLLPP LGIAIAVIII FYCYRVHRQQ KLSPSWESSK PRKLMDFSDN 240 241 CAIILEDDRS DISSTCANNI NHNTELLPIE LDTLVGKGRF AEVYKAKLKQ NTSEQFETVA 300 301 VKIFPYEEYS SWKTEKDIFS DINLKHENIL QFLTAEERKT ELGKQYWLIT AFHAKGNLQE 360 361 YLTRHVISWE DLRKLGSSLA RGIAHLHSDH TPCGRPKMPI VHRDLKSSNI LVKNDLTCCL 420 421 CDFGLSLRLD PTLSVDDLAN SGQVGTARYM APEVLESRMN LENVESFKQT DVYSMALVLW 480 481 EMTSRCNAVG EVKDYEPPFG SKVREHPCVE SMKDSVLRDR GRPEIPSFWL NHQGIQIVCE 540 541 TLTECWDHDP EARLTAQCVA ERFSELEHPE RLSGRSCSQE KIPEDGSLNT TK |
NOT SHOWING SINGLE HITS. [ Show Single Hits ]
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Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.12 |
Source: Reynolds et al. (2008)