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Protein Overview: FBpp0307684, FBp...

General Information:
Name(s) found: FBpp0307684 [FlyBase]
FBpp0307683 [FlyBase]
Description(s) found:
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  • gi|24643840|ref|NP_730783.1| CG12582, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|23170551|gb|AAF52171.2| CG12582, isoform B [Drosophila melanogaster] [NCBI NR]
  • type=protein; loc=3R:join(24088..24494,24552..24648,24727..25015,27565..28044,28098..28519,29504..29884,29935..30195); ID=FBpp0307684; name=CG12582-PG; parent=FBgn0037215,FBtr0336703; dbxref=FlyBase:FBpp0307684,FlyBase_Annotation_IDs:CG12582-PG,REFSEQ:NP_001262241,GB_protein:AGB95624; MD5=a5a4adfc0edaefa1983e4077dd3f3591; length=778; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=3R:join(24088..24494,24552..24648,24727..25015,27565..28044,28098..28519,29504..29884,29935..30195); ID=FBpp0307683; name=CG12582-PF; parent=FBgn0037215,FBtr0336702; dbxref=FlyBase:FBpp0307683,FlyBase_Annotation_IDs:CG12582-PF,REFSEQ:NP_730783,GB_protein:AAF52171; MD5=a5a4adfc0edaefa1983e4077dd3f3591; length=778; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG12582 (CG12582, FBgn0037215). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:23029..30295. It has the cytological map location 81F6. Based on sequence similarity, it is predicted to have molecular function</span>: beta-mannosidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: carbohydrate metabolic process. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • type=protein; loc=3R:join(24088..24494,24552..24648,24727..25015,27565..28044,28098..28519,29504..29884,29935..30195); ID=FBpp0110511; name=CG12582-PB; parent=FBgn0037215,FBtr0111225; dbxref=FlyBase_Annotation_IDs:CG12582-PB,FlyBase:FBpp0110511,REFSEQ:NP_ [fly-100309-contam.fasta]
  • CG12582-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:join(24088..24494,24552..24648,24727..25015,27565..28044,28098..28519,29504..29884,29935..30195); ID=FBpp0110511; name=CG12582-PB; parent=FBgn0037215,FBtr0111225; dbxref=FlyBase_Annotation_IDs:CG12582-PB,FlyBase:FBpp0110511,REFSEQ:NP_730783,GB_protein:AAF52171; MD5=a5a4adfc0edaefa1983e4077dd3f3591; length=778; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:join(24088..24494,24552..24648,24727..25015,27565..28044,28098..28519,29504..29884,29935..30195); ID=FBpp0110511; name=CG12582-PB; parent=FBgn0037215,FBtr0111225; dbxref=FlyBase_Annotation_IDs:CG12582-PB,FlyBase:FBpp0110511,REFSEQ:NP_730783,GB_protein:AAF52171; MD5=a5a4adfc0edaefa1983e4077dd3f3591; length=778; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • CG12582, isoform B OS=Drosophila melanogaster GN=CG12582 PE=4 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:join(4198366..4198772,4198830..4198926,4199005..4199293,4201843..4202322,4202376..4202797,4203782..4204162,4204213..4204473); ID=FBpp0307683; name=CG12582-PF; parent=FBgn0037215,FBtr0336702; dbxref=FlyBase:FBpp0307683,FlyBase_Annotation_IDs:CG12582-PF,REFSEQ:NP_730783,GB_protein:AAF52171; MD5=a5a4adfc0edaefa1983e4077dd3f3591; length=778; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:join(4198366..4198772,4198830..4198926,4199005..4199293,4201843..4202322,4202376..4202797,4203782..4204162,4204213..4204473); ID=FBpp0307684; name=CG12582-PG; parent=FBgn0037215,FBtr0336703; dbxref=FlyBase:FBpp0307684,FlyBase_Annotation_IDs:CG12582-PG,REFSEQ:NP_001262241,GB_protein:AGB95624; MD5=a5a4adfc0edaefa1983e4077dd3f3591; length=778; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:join(4198366..4198772,4198830..4198926,4199005..4199293,4201843..4202322,4202376..4202797,4203782..4204162,4204213..4204473); ID=FBpp0307683; name=beta-Man-PF; parent=FBgn0037215,FBtr0336702; dbxref=FlyBase:FBpp0307683,FlyBase_Annotation_IDs:CG12582-PF,REFSEQ:NP_730783,GB_protein:AAF52171; MD5=a5a4adfc0edaefa1983e4077dd3f3591; length=778; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=3R:join(4198366..4198772,4198830..4198926,4199005..4199293,4201843..4202322,4202376..4202797,4203782..4204162,4204213..4204473); ID=FBpp0307684; name=beta-Man-PG; parent=FBgn0037215,FBtr0336703; dbxref=FlyBase:FBpp0307684,FlyBase_Annotation_IDs:CG12582-PG,REFSEQ:NP_001262241,GB_protein:AGB95624; MD5=a5a4adfc0edaefa1983e4077dd3f3591; length=778; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of Q9VMY5, CG12582, isoform F OS=Drosophila melanogaster GN=beta-Man PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0307683 type=protein; loc=3R:join(4198366..4198772,4198830..4198926,4199005..4199293,4201843..4202322,4202376..4202797,4203782..4204162,4204213..4204473); ID=FBpp0307683; name=beta-Man-PF; parent=FBgn0037215,FBtr0336702; dbxref=FlyBase:FBpp0307683,FlyBase_Annotation_IDs:CG12582-PF,REFSEQ:NP_730783,GB_protein:AAF52171; MD5=a5a4adfc0edaefa1983e4077dd3f3591; length=778; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0307684 type=protein; loc=3R:join(4198366..4198772,4198830..4198926,4199005..4199293,4201843..4202322,4202376..4202797,4203782..4204162,4204213..4204473); ID=FBpp0307684; name=beta-Man-PG; parent=FBgn0037215,FBtr0336703; dbxref=FlyBase:FBpp0307684,FlyBase_Annotation_IDs:CG12582-PG,REFSEQ:NP_001262241,GB_protein:AGB95624; MD5=a5a4adfc0edaefa1983e4077dd3f3591; length=778; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:join(4198366..4198772,4198830..4198926,4199005..4199293,4201843..4202322,4202376..4202797,4203782..4204162,4204213..4204473); ID=FBpp0307683; name=beta-Man-PF; parent=FBgn0037215,FBtr0336702; dbxref=FlyBase:FBpp0307683,FlyBase_Annotation_IDs:CG12582-PF,REFSEQ:NP_730783,GB_protein:AAF52171,UniProt/TrEMBL:Q0KIE6; MD5=a5a4adfc0edaefa1983e4077dd3f3591; length=778; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=3R:join(4198366..4198772,4198830..4198926,4199005..4199293,4201843..4202322,4202376..4202797,4203782..4204162,4204213..4204473); ID=FBpp0307684; name=beta-Man-PG; parent=FBgn0037215,FBtr0336703; dbxref=FlyBase:FBpp0307684,FlyBase_Annotation_IDs:CG12582-PG,REFSEQ:NP_001262241,GB_protein:AGB95624,UniProt/TrEMBL:Q0KIE6; MD5=a5a4adfc0edaefa1983e4077dd3f3591; length=778; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 778 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: carbohydrate metabolic process [IEA]
    Molecular Function: beta-mannosidase activity [ISS]
    cation binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFVRYSYEVS SLLQAENFLE VEIQSPVVAA LARANALKEA KKSVPPECPN ERYHGECHMN  60
   61 MLRKMQASFS WDWGPAAPSA GIWKNVELEI YEVAVIREVD VDVSRVNGSY WNMHIRCFLD 120
  121 AGGWQNFNGR LVLYAVELLD RPVVVDRYAI KNISHLAPVI EFDQAVPNGK VVTWWPNGYG 180
  181 EQKLYPLHFT LKTWLGPDGP EVRSKTKSHK SLRVGFRTLD LVEDPAPDGV GNTFLFRVNG 240
  241 VEMFMKGSNY IPSHLLPEMQ TNEQISHLLR SAKEAHMNML RVWGGGVYES DYFYQLADSL 300
  301 GLLIWQDMMF ACAMYPVNDE FLSSVREEVR QNAMRLSHHP SVAIFVTNNE NEAALVQNWY 360
  361 GTLFERDRFE SEYRELYLAN VIHELKLVSH SSRPQPLVSS PSNGKASEPD NYISSNPQDN 420
  421 QNGDVHFYDY TKDGWDPGIF PRPRFVSEFG FQSFPGAYAW QRSKGEDDDL LGLITHRQHH 480
  481 PLGNVPVIAL VERHLPLPFP ENENYATALI YFSQIAQAMA TKVETELYRS LRDTPHRTMG 540
  541 ALYWQLNDVW VAPSWSSIDF YGNWKLLHYW ARDFLAPISI VALYEKSTDS LNISLICDQL 600
  601 EVDPRELNVV ANVHLWSQLL PRQSTSWDVT LRPNGVQYDK VIAISDLLQG EFTRTNAFLE 660
  661 LQLRRGQDVI SRTHFFPSSI AGAVGIEDPG LEFEIASRTC LNTTNVVRNS VSISIQVKRP 720
  721 AVFVYLELLK PYRYTLSENG FMQTEPMHVV YLTFDAPLCA RLLRKSDLRV LTVNDFMR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..778] PSI-BLAST 130.0 No description for 2je8A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity, hydrolyzing O-glycosyl compounds
    		•  5.00738488874746 bayes_pls_golite062009
  • hydrolase activity, acting on glycosyl bonds
    		•  4.76262930083697 bayes_pls_golite062009
  • hydrolase activity
    		•  3.98075336331567 bayes_pls_golite062009
  • mannosidase activity
    		•  2.76650385192253 bayes_pls_golite062009
  • beta-mannosidase activity
    		•  2.49892155617658 bayes_pls_golite062009
  • catalytic activity
    		•  1.85569074294201 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  1.72953375487082 bayes_pls_golite062009
  • hexosaminidase activity
    		•  1.58801560896878 bayes_pls_golite062009
  • galactosidase activity
    		•  1.26155841119987 bayes_pls_golite062009
  • fucose binding
    		•  0.74796375141119 bayes_pls_golite062009
  • beta-N-acetylhexosaminidase activity
    		•  0.672371394066443 bayes_pls_golite062009
  • peptidase activity
    		•  0.618122797487524 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.340224150705178 bayes_pls_golite062009
  • binding
    		•  0.207604764313869 bayes_pls_golite062009
  • glucosidase activity
    		•  0.156515120651346 bayes_pls_golite062009
  • alpha-glucosidase activity
    		•  0.136349550054069 bayes_pls_golite062009
  • protein kinase activity
    		•  0.07005412193767 bayes_pls_golite062009
  • sugar binding
    		•  0.0682120180274 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.0314396118267717 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle