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Protein Overview: ECP5_MOUSE

General Information:
Name(s) found: ECP5_MOUSE [Swiss-Prot]
Description(s) found:
Found 19 descriptions.
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  • Eosinophil cationic-type ribonuclease 5 OS=Mus musculus GN=Ear5 PE=1 SV=1 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 155 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: nucleic acid binding [IEA]
    endonuclease activity [IEA]
    nuclease activity [IEA]
    pancreatic ribonuclease activity [IEA]
    hydrolase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLKLLESRL CLLLLLGLVL TLVSCQRPTP SQKFAIQHIY KKSSPKCDDA MRVVNKYTGK  60
   61 CKDLNTFLHT TFADVVRVCH NPPKTCKDGT SPNCHDSSSK VSVTICKLTK RARNYTHCRY 120
  121 KTTGGKKSYT VACNPRTPKD RPTYPVVPVH LDRLF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..155] PSI-BLAST 50.30103 Ribonuclease A (also ribonuclease B, S)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ribonuclease activity
    		•  5.85331424069985 bayes_pls_golite062009
  • heparin binding
    		•  3.58380117228366 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  3.52657253958322 bayes_pls_golite062009
  • pattern binding
    		•  3.51086739633778 bayes_pls_golite062009
  • polysaccharide binding
    		•  3.37691389332571 bayes_pls_golite062009
  • carbohydrate binding
    		•  2.89194903289209 bayes_pls_golite062009
  • receptor binding
    		•  2.83930957790412 bayes_pls_golite062009
  • nuclease activity
    		•  2.6143896131521 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  2.55451546641661 bayes_pls_golite062009
  • hydrolase activity
    		•  2.48814110093195 bayes_pls_golite062009
  • copper ion binding
    		•  2.3834238539949 bayes_pls_golite062009
  • binding
    		•  1.86332796702086 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.54332419426054 bayes_pls_golite062009
  • catalytic activity
    		•  1.25983854650131 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.00514730781388 bayes_pls_golite062009
  • DNA binding
    		•  0.985618596844344 bayes_pls_golite062009
  • transition metal ion binding
    		•  0.977421234494784 bayes_pls_golite062009
  • protein binding
    		•  0.880608437208074 bayes_pls_golite062009
  • endonuclease activity
    		•  0.716350502288269 bayes_pls_golite062009
  • ion binding
    		•  0.398016681127412 bayes_pls_golite062009
  • endoribonuclease activity
    		•  0.390109603204743 bayes_pls_golite062009
  • cation binding
    		•  0.386926137029917 bayes_pls_golite062009
  • metal ion binding
    		•  0.386926137029917 bayes_pls_golite062009
  • RNA binding
    		•  0.25908919754622 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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