Protein Overview: HSF1_MOUSE

General Information:
Name(s) found:	HSF1_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|22654251\|sp\|P38532.2\|HSF1_MOUSE RecName: Full=Heat shock factor protein 1; Short=HSF 1; AltName: Full=Heat shock transcription factor 1; Short=HSTF 1 [NCBI NR] gi\|148697627\|gb\|EDL29574.1\| heat shock factor 1, isoform CRA_f [Mus musculus] [NCBI NR] Heat shock factor protein 1 OS=Mus musculus GN=Hsf1 PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):15-76710206 Splice isoform 2 of P38532 Heat shock factor protein 1 [hmr_yeast5_DM3-1_pombe.fasta] Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1) [nrdb_11152004_Chlamydomonas] Splice Isoform 2 of Heat shock factor protein 1 [ipi.MOUSE.v3.06.fasta] Tax_Id=10090 Splice Isoform 2 of Heat shock factor protein 1 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] heat shock factor 1, isoform CRA_f [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 SPLICE ISOFORM 1 OF HEAT SHOCK FACTOR PROTEIN 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Hsf1 Isoform 2 of Heat shock factor protein 1 [mouse-ipi-250309-contam.fasta] Tax_Id=10090 Gene_Symbol=Hsf1 Isoform 2 of Heat shock factor protein 1 ENSMUSG00000022556 IPI00132662 IPI00230223 IPI00742281 [IPIxENS.MOUSE_plus_REVERSE.fasta] IPI:IPI00132662.2\|SWISS-PROT:P38532-1\|ENSEMBL:ENSMUSP00000023215 Tax_Id=10090 Gene_Symbol=Hsf1 Isoform 2 of Heat shock factor protein 1 [ipi.MOUSE.fasta.20090209] Isoform 2 of Heat shock factor protein 1 OS=Mus musculus GN=Hsf1 [011711_HMR.fasta] sp\|P38532\|HSF1_MOUSE Heat shock factor protein 1 OS=Mus musculus GN=Hsf1 PE=1 SV=2 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	525 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] cytoplasm [IDA] pronucleus [IDA] protein complex [IPI]
Biological Process:	transcription [IEA] negative regulation of cell proliferation [IGI] spermatogenesis [IGI] regulation of transcription, DNA-dependent [IEA] regulation of transcription [IEA] embryonic process involved in female pregnancy [IMP] protein amino acid phosphorylation [IDA] defense response [UNKNOWN] response to stress [IEA] embryonic placenta development [IMP] positive regulation of multicellular organism growth [IMP] response to heat [IMP] in utero embryonic development [IMP] response to lipopolysaccharide [IMP] negative regulation of tumor necrosis factor production [IMP]
Molecular Function:	DNA binding [IDA] transcription factor activity [IEA] sequence-specific DNA binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLAVGPGAA GPSNVPAFLT KLWTLVSDPD TDALICWSPS GNSFHVFDQG QFAKEVLPKY  60
   61 FKHNNMASFV RQLNMYGFRK VVHIEQGGLV KPERDDTEFQ HPCFLRGQEQ LLENIKRKVT 120
  121 SVSTLKSEDI KIRQDSVTRL LTDVQLMKGK QECMDSKLLA MKHENEALWR EVASLRQKHA 180
  181 QQQKVVNKLI QFLISLVQSN RILGVKRKIP LMLSDSNSAH SVPKYGRQYS LEHVHGPGPY 240
  241 SAPSPAYSSS SLYSSDAVTS SGPIISDITE LAPTSPLASP GRSIDERPLS SSTLVRVKQE 300
  301 PPSPPHSPRV LEASPGRPSS MDTPLSPTAF IDSILRESEP TPAASNTAPM DTTGAQAPAL 360
  361 PTPSTPEKCL SVACLDKNEL SDHLDAMDSN LDNLQTMLTS HGFSVDTSAL LDLFSPSVTM 420
  421 PDMSLPDLDS SLASIQELLS PQEPPRPIEA ENSNPDSGKQ LVHYTAQPLF LLDPDAVDTG 480
  481 SSELPVLFEL GESSYFSEGD DYTDDPTISL LTGTEPHKAK DPTVS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: HSF1_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: