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Protein Overview: XRN2_SCHPO

General Information:
Name(s) found: XRN2_SCHPO [Swiss-Prot]
Description(s) found:
Found 2 descriptions.
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  • 5'-3' exoribonuclease 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=dhp1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Schizosaccharomyces pombe 972h-
    Length: 991 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGVPALFRLL SRKFAKVITP VIEAPTEKLP DGTEIEPDLS LPNPNGVECD NLYLDMNGIV  60
   61 HPCSHPEDRP APETEDEMMV AVFEYTDRIL AMVRPRQLLF IAIDGVAPRA KMNQQRSRRF 120
  121 RSSREAALKE EELQAFIEEA KQQGIPIDEN ATKKKSWDSN CITPGTPFMD TLAKSLRYYI 180
  181 INKLNSDPCW RNVRFILSDA SVPGEGEHKI MEFIRSQRVK PEYDPNTHHV VYGLDADLIM 240
  241 LGLATHEPHF RVLREDVFFQ QGSTKKTKEE RLGIKRLDDV SETNKVPVKK PFIWLNVSIL 300
  301 REYLEVELYV PNLPFPFDLE RAIDDWVFFI FFVGNDFLPH LPSLDIRDGA VERLTEIWRA 360
  361 SLPHMGGYLT LDGSVNLARA EVILSAVGNQ EDDIFKRLKQ QEDRRNENYR RRQQRESNQE 420
  421 SESYVDNVVI QRSVETQSTE VVTSSKSTSV DTKPPKKTQK IDAPAPVDLV NLSEKTSNRS 480
  481 LGATNRELIN NRAANRLGLS REAAAVSSVN KLAASALKAQ LVSNETLQNV PLEDSIASSS 540
  541 AYEDTDSIES STPVVHPIDT KVSNVGQKRK APDSTEENEN TDTVRLYEPG YRERYYEQKF 600
  601 HISPDEPEKI REAVKHYVHG LCWVLLYYYQ GCPSWTWYYP YHYAPFAADF KDLASIDVKF 660
  661 ELNQPFKPYE QLLGVLPAAS KNNLPEKLQT LMTDENSEII DFYPENFTID LNGKKFEWQG 720
  721 VALLPFIDEN RLLNAVSKIY PQLTEEESKR NEDGSTLLFI SEHHPMFSEL VKQLYSKKRQ 780
  781 GKPLKLSGKM AHGLFGKVNT NDSVIPNVSV QCPIDVTSAD ALQKYGSIDD NQSISLVFEV 840
  841 PKSHFVHKSM LLRGVKMPNR VLTPEDINQV RAERSFSSRR NNGNSYRGGH QSYGVRRSYQ 900
  901 SQSYSSRQSY TGVTNGFANG GVQPPWSGNG NFPRSNASYN SRGGHEGYGG RSRGGGYSNG 960
  961 PPAGNHYSSN RGKGYGYQRE SYNNNNRNGY Y

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..506] FFAS03 1.58 Crystal structure of the human FEN1-PCNA complex
    2 View Details [507..710] MSA 2.067953 View MSA. No confident structure predictions are available.
    3 View Details [711..778] deduced N/A No confident structure predictions are available.
    4 View Details [779..991] PSI-BLAST 15.30103 No description for 1y0fB was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • DNA binding
    		•  2.74395891269151 bayes_pls_golite062009
  • binding
    		•  2.58539672241253 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.54722210455433 bayes_pls_golite062009
  • endonuclease activity
    		•  1.2840172881923 bayes_pls_golite062009
  • flap endonuclease activity
    		•  1.17726395799783 bayes_pls_golite062009
  • endodeoxyribonuclease activity
    		•  1.12391156671522 bayes_pls_golite062009
  • deoxyribonuclease activity
    		•  1.11025090301954 bayes_pls_golite062009
  • endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  1.07360773846975 bayes_pls_golite062009
  • protein binding
    		•  0.695466920831325 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.657224027340282 bayes_pls_golite062009
  • catalytic activity
    		•  0.585392957294978 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle