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Protein Overview: NB5R2_MOUSE

General Information:
Name(s) found: NB5R2_MOUSE [Swiss-Prot]
Description(s) found:
Found 22 descriptions.
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  • NADH-cytochrome b5 reductase 2 OS=Mus musculus GN=Cyb5r2 PE=2 SV=2 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 276 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDA]
    Biological Process: biological_process [ND]
    lipid biosynthetic process [IEA]
    oxidation reduction [IEA]
    steroid biosynthetic process [IEA]
    sterol biosynthetic process [IEA]
    Molecular Function: cytochrome-b5 reductase activity [IEA]
    oxidoreductase activity [IEA]
    molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVKKKDLIT LQDPEAKYPL PLIEKEQISH NTRRFRFGLP SPDHVLGLPV GNYVHLLAQI  60
   61 NNELVIRAYT PVSSDDDQGF VDLIIKIYFK NVHPKYPEGG KMTQYLENMK IGDTILFRGP 120
  121 TGRLFYNEPG TLLIKANKTS EPEKKLVHHL GMIAGGTGIT PMLQLIRHIT KDTSDETRMS 180
  181 LLFANQTEED ILLRKELEEV ATTHHKQFNL WYTLDRPPSD WKYSSGFVSA DMIKEHLPPP 240
  241 GEDTLILVCG PPPLIQAAAH PSLEQLSYTK DMIFIY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..276] PSI-BLAST 67.221849 cytochrome b5 reductase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity, acting on NADH or NADPH
    		•  5.12164086042432 bayes_pls_golite062009
  • NADH dehydrogenase (ubiquinone) activity
    		•  4.82719560919736 bayes_pls_golite062009
  • NADH dehydrogenase activity
    		•  4.10258111244259 bayes_pls_golite062009
  • NADH dehydrogenase (quinone) activity
    		•  3.98767523940821 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  3.81212227280399 bayes_pls_golite062009
  • coenzyme binding
    		•  3.33805077160148 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor
    		•  3.111558299994 bayes_pls_golite062009
  • oxidoreductase activity
    		•  3.02740987944465 bayes_pls_golite062009
  • FAD binding
    		•  2.07600122867642 bayes_pls_golite062009
  • arginine binding
    		•  1.58854105635357 bayes_pls_golite062009
  • cytochrome-b5 reductase activity
    		•  1.5685421124725 bayes_pls_golite062009
  • binding
    		•  1.56341797572673 bayes_pls_golite062009
  • ferredoxin-NADP+ reductase activity
    		•  1.46342400843015 bayes_pls_golite062009
  • oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor
    		•  1.46342400843015 bayes_pls_golite062009
  • ferredoxin reductase activity
    		•  1.46342400843015 bayes_pls_golite062009
  • catalytic activity
    		•  1.45374095556065 bayes_pls_golite062009
  • tetrahydrobiopterin binding
    		•  1.29331444558985 bayes_pls_golite062009
  • monooxygenase activity
    		•  1.24895114339483 bayes_pls_golite062009
  • NADP or NADPH binding
    		•  1.18833847639357 bayes_pls_golite062009
  • demethylase activity
    		•  1.1768217851058 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
    		•  1.11231803143399 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors
    		•  0.90349352746963 bayes_pls_golite062009
  • oxidoreductase activity, acting on iron-sulfur proteins as donors
    		•  0.73475657802914 bayes_pls_golite062009
  • transferase activity
    		•  0.708491789248912 bayes_pls_golite062009
  • FMN binding
    		•  0.649158247260553 bayes_pls_golite062009
  • riboflavin synthase activity
    		•  0.380537461428523 bayes_pls_golite062009
  • cofactor binding
    		•  0.205324283520452 bayes_pls_golite062009
  • protein binding
    		•  0.144900113694048 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.87

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle