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Protein Overview: gi|1651560, gi|8...

General Information:
Name(s) found: gi|89107982 [NCBI NR]
gi|1651560 [NCBI NR]
Description(s) found:
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  • gi|89107982|ref|AP_001762.1| isocitrate dehydrogenase, specific for NADP+ [Escherichia coli str. K-12 substr. W3110] [NCBI NR]
  • gi|1651560|dbj|BAA35958.1| isocitrate dehydrogenase, specific for NADP+ [Escherichia coli str. K12 substr. W3110] [NCBI NR]
  • isocitrate dehydrogenase, specific for NADP+ [Escherichia coli W3110] [nr-271106-contam.fasta]
  • isocitrate dehydrogenase, specific for NADP+ [Escherichia coli str. K-12 substr. W3110] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
    • Organism: Escherichia coli str. K-12 substr. W3110
    Length: 416 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESKVVVPAQ GKKITLQNGK LNVPENPIIP YIEGDGIGVD VTPAMLKVVD AAVEKAYKGE  60
   61 RKISWMEIYT GEKSTQVYGQ DVWLPAETLD LIREYRVAIK GPLTTPVGGG IRSLNVALRQ 120
  121 ELDLYICLRP VRYYQGTPSP VKHPELTDMV IFRENSEDIY AGIEWKADSA DAEKVIKFLR 180
  181 EEMGVKKIRF PEHCGIGIKP CSEEGTKRLV RAAIEYAIAN DRDSVTLVHK GNIMKFTEGA 240
  241 FKDWGYQLAR EEFGGELIDG GPWLKVKNPN TGKEIVIKDV IADAFLQQIL LRPAEYDVIA 300
  301 CMNLNGDYIS DALAAQVGGI GIAPGANIGD ECALFEATHG TAPKYAGQDK VNPGSIILSA 360
  361 EMMLRHMGWT EAADLIVKGM EGAINAKTVT YDFERLMDGA KLLKCSEFGD AIIENM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..416] PSI-BLAST 143.0 ISOCITRATE DEHYDROGENASE: STRUCTURE OF AN ENGINEERED NADP+--> NAD+ SPECIFICITY-REVERSAL MUTANT

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • isocitrate dehydrogenase (NAD+) activity
    		•  5.9567768649084 bayes_pls_golite062009
  • isocitrate dehydrogenase activity
    		•  5.76817846591752 bayes_pls_golite062009
  • 3-isopropylmalate dehydrogenase activity
    		•  4.43187390953534 bayes_pls_golite062009
  • isocitrate dehydrogenase (NADP+) activity
    		•  3.47645456015586 bayes_pls_golite062009
  • malate dehydrogenase activity
    		•  3.17013707624362 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.74237430402883 bayes_pls_golite062009
  • catalytic activity
    		•  2.71251959637136 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  2.46799258909805 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  2.38235863668553 bayes_pls_golite062009
  • binding
    		•  0.768867938429375 bayes_pls_golite062009
  • malic enzyme activity
    		•  0.483776792839856 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  0.466038297142601 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle