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Protein Overview: TKN1_MOUSE

General Information:
Name(s) found: TKN1_MOUSE [Swiss-Prot]
Description(s) found:
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  • gi|6678207|ref|NP_033337.1| tachykinin 1 [Mus musculus] [NCBI NR]
  • gi|449859|prf||1920220A prepro-tachykinin A [NCBI NR]
  • gi|435121|dbj|BAA04508.1| beta-preprotachykinin A [Mus musculus] [NCBI NR]
  • pir||I52526 neurokinin 1 precursor - mouse [NCBI NR]
  • gi|148681999|gb|EDL13946.1| tachykinin 1, isoform CRA_b [Mus musculus] [NCBI NR]
  • gi|1174706|sp|P41539.1|TKN1_MOUSE RecName: Full=Protachykinin-1; AltName: Full=PPT; Contains: RecName: Full=Substance P; Contains: RecName: Full=Neurokinin A; Short=NKA; AltName: Full=Substance K; AltName: Full=Neuromedin L; Contains: RecName: Full=Neurop [NCBI NR]
  • gi|111600503|gb|AAI19123.1| Tachykinin 1 [Mus musculus] [NCBI NR]
  • gi|109733202|gb|AAI17082.1| Tachykinin 1 [Mus musculus] [NCBI NR]
  • Protachykinin-1 OS=Mus musculus GN=Tac1 PE=2 SV=1 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):None Splice isoform Beta of P41539 Protachykinin 1 precursor [hmr_yeast5_DM3-1_pombe.fasta]
  • tachykinin 1; substance P; neurokinin 1; preprotachykinin A; neurokinin A [HMR_022704-rand.fasta]
  • Splice Isoform Beta of Protachykinin 1 precursor [ipi.MOUSE.v3.06.fasta]
  • tachykinin 1 [Mus musculus]gi|435121|dbj|BAA04508.1| beta-preprotachykinin A [Mus musculus]gi|1174706|sp|P41539|TKN1_MOUSE Protachykinin 1 precursor (PPT) [Contains: Substance P; Neurokinin A (NKA) (Substance K) (Neuromedin L); Neuropeptide K (NPK); Neu [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10090 Splice Isoform Beta of Protachykinin 1 precursor [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta]
  • (NM_009311) tachykinin 1; substance P; neurokinin 1; preprotachykinin A; neurokinin A [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • tachykinin 1 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • Protachykinin-1 precursor (PPT) [Contains: Substance P; Neurokinin A (NKA) (Substance K) (Neuromedin L); Neuropeptide K (NPK); Neuropeptide gamma; C-terminal-flanking peptide] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • tachykinin 1, isoform CRA_b [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tachykinin 1 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • beta-preprotachykinin A [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • prepro-tachykinin A [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10090 SPLICE ISOFORM 1 OF PROTACHYKININ 1 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Tac1 Isoform Beta of Protachykinin-1 [mouse-ipi-250309-contam.fasta]
  • Tax_Id=10090 Gene_Symbol=Tac1 Isoform Beta of Protachykinin-1 precursor [ipi.MOUSE_jw_12may08.contam.fasta]
  • Protachykinin 1 precursor (PPT) [Contains: Substance P; Neurokinin A (NKA) (Substance K) (Neuromedin L); Neuropeptide K (NPK); Neuropeptide gamma; C-terminal-flanking peptide] [nr-271106-contam.fasta]
  • Tax_Id=10090 Gene_Symbol=Tac1 Isoform Beta of Protachykinin 1 precursor [zeeyong.fasta]
  • Tax_Id=10090 Gene_Symbol=Tac1 Isoform Beta of Protachykinin 1 precursor ENSMUSG00000061762 IPI00114504 IPI00223287 [IPIxENS.MOUSE_plus_REVERSE.fasta]
  • protachykinin-1 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta]
  • IPI:IPI00114504.1|SWISS-PROT:P41539-1|TREMBL:Q149W7|ENSEMBL:ENSMUSP00000088175|REFSEQ:NP_033337 Tax_Id=10090 Gene_Symbol=Tac1 Isoform Beta of Protachykinin-1 [ipi.MOUSE.fasta.20090209]
  • Isoform Beta of Protachykinin-1 OS=Mus musculus GN=Tac1 [011711_HMR.fasta]
  • sp|P41539|TKN1_MOUSE Protachykinin-1 OS=Mus musculus GN=Tac1 PE=2 SV=1 [uniprot.sptr.mouse.20130102]
  • tr|Q149W7|Q149W7_MOUSE Tachykinin 1 OS=Mus musculus GN=Tac1 PE=2 SV=1 [uniprot.sptr.mouse.20130102]
  • Tachykinin 1 OS=Mus musculus GN=Tac1 PE=2 SV=1 [mouse-uniprot-290313-contam.fasta]
    • Organism: Mus musculus
    Length: 130 amino acids

    Gene Ontology:
    Cellular Component: extracellular space [UNKNOWN]
    neuronal cell body [IDA]
    extracellular region [IDA]
    axon [IDA]
    plasma membrane [UNKNOWN]
    Biological Process: positive regulation of synaptic transmission, GABAergic [UNKNOWN]
    synaptic transmission [IEA]
    response to hormone stimulus [UNKNOWN]
    associative learning [UNKNOWN]
    tachykinin receptor signaling pathway [IEA]
    positive regulation of natriuresis [UNKNOWN]
    regulation of blood pressure [UNKNOWN]
    elevation of cytosolic calcium ion concentration [UNKNOWN]
    positive regulation of acute inflammatory response [UNKNOWN]
    response to pain [IMP]
    long-term memory [UNKNOWN]
    neuropeptide signaling pathway [IEA]
    inflammatory response [IDA]
    positive regulation of action potential [UNKNOWN]
    positive regulation of lymphocyte proliferation [UNKNOWN]
    positive regulation of stress fiber assembly [UNKNOWN]
    positive regulation of synaptic transmission, cholinergic [UNKNOWN]
    sensory perception of pain [IMP]
    negative regulation of heart rate [UNKNOWN]
    positive regulation of epithelial cell migration [UNKNOWN]
    Molecular Function: substance P receptor binding [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKILVAVAVF FLVSTQLFAE EIDANDDLNY WSDWSDSDQI KEAMPEPFEH LLQRIARRPK  60
   61 PQQFFGLMGK RDADSSVEKQ VALLKALYGH GQISHKRHKT DSFVGLMGKR ALNSVAYERS 120
  121 AMQNYERRRK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..130] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle