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Protein Overview: sdt-PH

General Information:
Name(s) found: sdt-PH / FBpp0110333 [FlyBase]
Description(s) found:
Found 16 descriptions.
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  • The gene stardust is referred to in FlyBase by the symbol Dmel\sdt (CG32717, FBgn0243505). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:8072582..8133487. It has the cytological map location 7D17-7D22. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: establishment or maintenance of neuroblast polarity; zonula adherens assembly; establishment or maintenance of polarity of embryonic epithelium; establishment or maintenance of epithelial cell apical/basal polarity. 53 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; salivary gland; zonula adherens; amnioserosa; embryonic epidermis; photoreceptor cell stalk; trachea; spot adherens junction; macrophage; embryo. It has 7 annotated transcripts and 7 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 934 amino acids

    Gene Ontology:
    Cellular Component: apicolateral plasma membrane [IDA]
    adherens junction [IDA]
    subapical complex [TAS]
    cell-cell adherens junction [NAS]
    cytoplasm [NAS]
    membrane [ISS][NAS]
    septate junction [TAS]
    apical cortex [IDA]
    plasma membrane [ISS]
    apical plasma membrane [IDA][NAS][TAS]
    Biological Process: [NOT]establishment or maintenance of neuroblast polarity [IEP][IMP]
    cell-cell junction assembly [NAS]
    morphogenesis of an epithelium [NAS][TAS]
    zonula adherens assembly [IMP][TAS]
    establishment or maintenance of epithelial cell apical/basal polarity [IEP][IMP][IPI][TAS]
    establishment or maintenance of cell polarity [NAS]
    morphogenesis of a polarized epithelium [TAS]
    establishment or maintenance of polarity of embryonic epithelium [IMP]
    Molecular Function: protein binding [IPI][ISS][TAS]
    guanylate kinase activity [ISS][NAS][TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRILKQWNRR RSGSSIVVLD GDDLKPCLPD DYISGQHHLN HQQQLQLQQQ LQQQHPLQQQ  60
   61 HYRTHSGDIR EIDQEMLTML SVNQDNGPHR EMAVDCPDTF IARNKTPPRY PPPRPPQLNG 120
  121 NAKPVPPPRD HLRVEKDGRL VNCSPAPQLP DRRAPGNASS GSSGATTHPL QHQQIAQIVE 180
  181 PTLEQLDSIK KYQEQLRRRR EEEERIAQQN EFLRNSLRGS RKLKALQDTA TPGKAVAQQQ 240
  241 QQATLATQVV GVENEAYLPD EDQPQAEQID GYGELIAALT RLQNQLSKSG LSTLAGRVSA 300
  301 AHSVLASASV AHVLAARTAV LQRRRSRVSG PLHHSSLGLQ KDIVELLTQS NTAAAIELGN 360
  361 LLTSHEMEGL LLAHDRIANH TDGTPSPTPT PTPAIGAATG STLSSPVAGP KRNLGMVVPP 420
  421 PVVPPPLAQR GAMPLPRGES PPPVPMPPLA TMPMSMPVNL PMSACFGTLN DQNDNIRIIQ 480
  481 IEKSTEPLGA TVRNEGEAVV IGRIVRGGAA EKSGLLHEGD EILEVNGQEL RGKTVNEVCA 540
  541 LLGAMQGTLT FLIVPAGSPP SVGVMGGTTG SQLAGLGGAH RDTAVLHVRA HFDYDPEDDL 600
  601 YIPCRELGIS FQKGDVLHVI SREDPNWWQA YREGEEDQTL AGLIPSQSFQ HQRETMKLAI 660
  661 AEEAGLARSR GKDGSGSKGA TLLCARKGRK KKKKASSEAG YPLYATTAPD ETDPEEILTY 720
  721 EEVALYYPRA THKRPIVLIG PPNIGRHELR QRLMADSERF SAAVPHTSRA RREGEVPGVD 780
  781 YHFITRQAFE ADILARRFVE HGEYEKAYYG TSLEAIRTVV ASGKICVLNL HPQSLKLLRA 840
  841 SDLKPYVVLV APPSLDKLRQ KKLRNGEPFK EEELKDIIAT ARDMEARWGH LFDMIIINND 900
  901 TERAYHQLLA EINSLEREPQ WVPAQWVHNN RDES

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..108] MSA 1.06797 View MSA. No confident structure predictions are available.
    2 View Details [109..332] deduced N/A No confident structure predictions are available.
    3 View Details [333..383] FFAS03 1.52 NMR structure of L27 heterodimer from C. elegans Lin-7 and H. sapiens Lin-2 scaffold proteins
    4 View Details [384..470] deduced N/A No confident structure predictions are available.
    5 View Details [471..571] PSI-BLAST 18.154902 Solution structure of the PDZ domain of Pals1 protein
    6 View Details [572..934] PSI-BLAST 56.0 Psd-95; Guanylate kinase-like domain of Psd-95

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • binding
    		•  3.2595117613307 bayes_pls_golite062009
  • nucleobase, nucleoside, nucleotide kinase activity
    		•  3.03529700765506 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.83180079733297 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.39826531242265 bayes_pls_golite062009
  • protein binding
    		•  2.35875654816667 bayes_pls_golite062009
  • nucleotide kinase activity
    		•  1.79696347300128 bayes_pls_golite062009
  • guanylate kinase activity
    		•  1.70730560221787 bayes_pls_golite062009
  • phosphotransferase activity, phosphate group as acceptor
    		•  1.69528181005421 bayes_pls_golite062009
  • signal transducer activity
    		•  1.51162321843898 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.51162321843898 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.00130123171287 bayes_pls_golite062009
  • protein domain specific binding
    		•  0.64214865642772 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.387065538161985 bayes_pls_golite062009
  • receptor binding
    		•  0.359972518335054 bayes_pls_golite062009
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.82

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle