Protein Overview: gi|55749557, gi|...

General Information:
Name(s) found:	gi\|55749557 [NCBI NR] gi\|27503514 [NCBI NR]
Description(s) found: Found 19 descriptions. SHOW ALL	gi\|55749557\|ref\|NP_001006611.1\| seven in absentia homolog 1 isoform b [Homo sapiens] [NCBI NR] gi\|27503514\|gb\|AAH42550.1\| Seven in absentia homolog 1 (Drosophila) [Homo sapiens] [NCBI NR]
Organism:	Homo sapiens
Length:	313 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTGKATPPSL YSWRGVLFTC LPAARTRKRK EMSRQTATAL PTGTSKCPPS QRVPALTGTT  60
   61 ASNNDLASLF ECPVCFDYVL PPILQCQSGH LVCSNCRPKL TCCPTCRGPL GSIRNLAMEK 120
  121 VANSVLFPCK YASSGCEITL PHTEKADHEE LCEFRPYSCP CPGASCKWQG SLDAVMPHLM 180
  181 HQHKSITTLQ GEDIVFLATD INLPGAVDWV MMQSCFGFHF MLVLEKQEKY DGHQQFFAIV 240
  241 QLIGTRKQAE NFAYRLELNG HRRRLTWEAT PRSIHEGIAT AIMNSDCLVF DTSIAQLFAE 300
  301 NGNLGINVTI SMC

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..132]	PSI-BLAST	13.522879	RAG1 DIMERIZATION DOMAIN
2	View Details	[133..313]	PSI-BLAST	55.154902	Crystal structure of Siah1 SBD bound to the peptide EKPAAVVAPITTG from SIP

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
ubiquitin-protein ligase activity	5.32809533104435	bayes_pls_golite062009
small conjugating protein ligase activity	5.17943669371679	bayes_pls_golite062009
acid-amino acid ligase activity	4.2482314105959	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	3.07217714843839	bayes_pls_golite062009
binding	2.15929427993458	bayes_pls_golite062009
protein binding	1.49775478023418	bayes_pls_golite062009
small conjugating protein-specific protease activity	0.786612602432575	bayes_pls_golite062009
ligase activity	0.63517530468004	bayes_pls_golite062009
peptidase activity	0.629020501929934	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	0.616462655649223	bayes_pls_golite062009
ubiquitin-specific protease activity	0.549461161056205	bayes_pls_golite062009
transcription regulator activity	0.181063140818134	bayes_pls_golite062009
cysteine-type peptidase activity	0.159023519781458	bayes_pls_golite062009
hydrolase activity	0.156835837705934	bayes_pls_golite062009
catalytic activity	0.14112008370434	bayes_pls_golite062009
nucleic acid binding	0.125491277540945	bayes_pls_golite062009

2

No functions predicted.

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

Philius confidence legend

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