Protein Overview: GNG12

General Information:
Name(s) found:	GNG12 [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|6563252\|gb\|AAF17220.1\|AF119663_1 G-protein gamma-12 subunit [Homo sapiens] [NCBI NR] gi\|6164871\|gb\|AAF04571.1\|AF188181_1 G-protein gamma 12 subunit [Homo sapiens] [NCBI NR] gi\|56204309\|emb\|CAI23496.1\| guanine nucleotide binding protein (G protein), gamma 12 [Homo sapiens] [NCBI NR] gi\|51036603\|ref\|NP_061329.3\| G-protein gamma-12 subunit [Homo sapiens] [NCBI NR] gi\|50949461\|emb\|CAH10645.1\| hypothetical protein [Homo sapiens] [NCBI NR] gi\|33150734\|gb\|AAP97245.1\|AF123766_1 G-protein gamma-12 subunit [Homo sapiens] [NCBI NR] gi\|20147651\|gb\|AAM12593.1\|AF493879_1 guanine nucleotide binding protein gamma 12 [Homo sapiens] [NCBI NR] gi\|158259663\|dbj\|BAF85790.1\| unnamed protein product [Homo sapiens] [NCBI NR] gi\|14039774\|gb\|AAK53385.1\| G protein gamma 12 subunit [Homo sapiens] [NCBI NR] gi\|12229817\|sp\|Q9UBI6.3\|GBG12_HUMAN RecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12; Flags: Precursor [NCBI NR] gi\|119626891\|gb\|EAX06486.1\| guanine nucleotide binding protein (G protein), gamma 12, isoform CRA_a [Homo sapiens] [NCBI NR] gi\|119626890\|gb\|EAX06485.1\| guanine nucleotide binding protein (G protein), gamma 12, isoform CRA_a [Homo sapiens] [NCBI NR] gi\|119626889\|gb\|EAX06484.1\| guanine nucleotide binding protein (G protein), gamma 12, isoform CRA_a [Homo sapiens] [NCBI NR] guanine nucleotide binding protein (G protein), gamma 12 [HGNC (HUGO)] Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 OS=Homo sapiens GN=GNG12 PE=1 SV=3 [Swiss-Prot] G-protein gamma-12 subunit [hmr_yeast5_DM3-1_pombe.fasta] G-protein gamma-12 subunit [Homo sapiens]gi\|33150734\|gb\|AAP97245.1\| G-protein gamma-12 subunit [Homo sapiens]gi\|20147651\|gb\|AAM12593.1\| guanine nucleotide binding protein gamma 12 [Homo sapiens]gi\|50949461\|emb\|CAH10645.1\| hypothetical protein [Homo sap [nrdb_11152004_Chlamydomonas] Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-12 subunit [Yateslab_human_na_07-28-2006_reversed.fasta] (NM_018841) G-protein gamma-12 subunit [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] G-protein gamma-12 subunit [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta] Tax_Id=9606 G-protein gamma-12 subunit [EBI-IPI_human_3.04_03-07-2005_reverse.fasta] Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 precursor [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] guanine nucleotide binding protein (G protein), gamma 12 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] guanine nucleotide binding protein (G protein), gamma 12, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] hypothetical protein [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] G protein gamma 12 subunit [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] guanine nucleotide binding protein gamma 12 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] G-protein gamma 12 subunit [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 G-PROTEIN GAMMA-12 SUBUNIT [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=GNG12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [human-ipi-250309-contam.fasta] G-protein gamma-12 subunit precursor [Homo sapiens] [NCBI-RefSeq_human_na_10-19-2009_con_reversed.fasta] Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-12 subunit precursor [nr-271106-contam.fasta] IPI:IPI00221232.9\|SWISS-PROT:Q9UBI6\|TREMBL:Q53GD1;Q69YP5\|ENSEMBL:ENSP00000360021\|REFSEQ:NP_061329\|H-INV:HIT000027343\|VEGA:OTTHUMP00000011139 Tax_Id=9606 Gene_Symbol=GNG12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [ipi.HUMAN.fasta.20090807] Tax_Id=9606 Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-12 subunit precursor [IPI_human_3.26.fasta] [human_BMb_040710_contam.fasta] Tax_Id=9606 Gene_Symbol=GNG12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-12 subunit precursor ENSG00000172380 IPI00221232 [drosphohumanreversed.fasta] Tax_Id=9606 Gene_Symbol=GNG12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-12 subunit precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta] guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 precursor [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Q9UBI6;Q9BRV5; RecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12; Flags: Precursor; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 OS=Homo sapiens GN=GNG12 [011711_HMR.fasta] GeneSymbol=GNG12 Synonyms=FLJ31352\|FLJ34695 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 precursor [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 GN=GNG12 [Doctor+uniprot-HUMAN-120911.fasta]
Organism:	Homo sapiens
Length:	72 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:
Sequence: [PDR BLAST] [ProtParam]	1 11 21 31 41 51 \| \| \| \| \| \| 1 MSSKTASTNN IAQARRTVQQ LRLEASIERI KVSKASADLM SYCEEHARSD PLLIGIPTSE 60 61 NPFKDKKTCI IL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..72]	PSI-BLAST	23.0	The Crystal Structure of a Biologically Active Peptide (SIGK) Bound to a G Protein Beta:Gamma Heterodimer

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
GTPase activity	5.98519752009234	bayes_pls_golite062009
angiotensin receptor binding	3.57083467421742	bayes_pls_golite062009
type 1 angiotensin receptor binding	3.57083467421742	bayes_pls_golite062009
signal transducer activity	1.75801578312445	bayes_pls_golite062009
molecular transducer activity	1.75801578312445	bayes_pls_golite062009
binding	1.46430715205084	bayes_pls_golite062009
receptor binding	1.45302453757621	bayes_pls_golite062009
G-protein-coupled receptor binding	0.842609851756611	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.725486261281146	bayes_pls_golite062009
pyrophosphatase activity	0.700350766348093	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.681263488423619	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.679963841904917	bayes_pls_golite062009
protein binding	0.399162858691971	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle