Protein Overview: gi|109484612

General Information:
Name(s) found:	gi\|109484612 [NCBI NR]
Description(s) found: Found 2 descriptions. SHOW ALL	gi\|109484612\|ref\|XP_001067729.1\| PREDICTED: similar to Zinc finger protein HRX (ALL-1) [Rattus norvegicus] [NCBI NR]
Organism:	Rattus norvegicus
Length:	3972 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IEA] nuclear part [UNKNOWN] histone methyltransferase complex [UNKNOWN][IEA] cellular_component [ND] MLL1 complex [UNKNOWN]
Biological Process:	chromatin modification [IEA] biological_process [ND] protein complex assembly [UNKNOWN] embryonic hemopoiesis [UNKNOWN] negative regulation of cell proliferation [UNKNOWN] anterior/posterior pattern formation [UNKNOWN] regulation of transcription, DNA-dependent [IEA] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN] histone H4-K16 acetylation [UNKNOWN] DNA methylation [UNKNOWN] positive regulation of transcription, DNA-dependent [UNKNOWN] regulation of histone H3-K4 methylation [UNKNOWN] histone H3-K4 methylation [UNKNOWN]
Molecular Function:	histone methyltransferase activity (H3-K4 specific) [UNKNOWN][IEA] DNA binding [IEA] zinc ion binding [UNKNOWN][IEA] identical protein binding [UNKNOWN] protein binding [UNKNOWN][IEA] protein homodimerization activity [UNKNOWN] histone acetyl-lysine binding [UNKNOWN] unmethylated CpG binding [UNKNOWN] chromatin binding [UNKNOWN] molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRKAEEKARS SGDPSSRAAL EVVLLGRSSP CASRERLPSP PHLPWRCRSR RAGHALIQVA  60
   61 GREEPGPGLG IEQWPPGGGG GGQEPICRLQ GRRAPPGARH SRPRGPALLR VGPGFDAALQ 120
  121 VSAAIGTNLR RFRAVFGESG GGGGSGEDEQ FLGFGSDEEV RVRSPTRSPS VKASPRKPRG 180
  181 RPRSGSDRNP AILSDPSVFS PLNKSETKST DKIKKKDSKS IEKKRGRPPT FPGVKIKITH 240
  241 GKDIAELTQG SKEDSLKKVK RTPSAMFQQA TKIKKLRAGK LSPLKSKFKT GKLQIGRKGV 300
  301 QIVRRRGRPP STERIKTPSG LLINSELEKP QKVRKDKEGT PPLTKEDKTV VRQSPRRIKP 360
  361 VRIIPSSKRT DATIAKQLLQ RAKKGAQKKI EKEAAQLQGR KVKTQVKNIR QFIMPVVSAI 420
  421 SSRIIKTPRR FIEDEDYDPP IKIARLESTP NSRFSATSCG SSEKSSAASQ HSSQMSSDSS 480
  481 RSSSPSIDTT SDSQASEEIQ ALPEERSNTP EVHTPLPISQ SPENESNDRR GRRYSMSERS 540
  541 FGSRTTKKLP TLQSAPQQQT SSSPPPPLLT PPPPLQPASG ISDHTPWLMP PTIPLASPFL 600
  601 PASAAPMQGK RKSILREPTF RWTSLKHSRS EPQYFSSAKY AKEGLIRKPI FDNFRPPPLT 660
  661 PEDVGFASGF SASGSAASAR LFSPLHSGTR FDIHKRSPIL RAPRFTPSEA HSRIFESVTL 720
  721 PSNRTSSGAS SSGVSNRKRK RKVFSPIRSE PRSPSHSMRT RSGRLSTSEL SPLTPPSSVS 780
  781 SSLSIPVSPL AASALNPTFT FPSHSLTQSG ESTEKSQRAR KQTSAPAEPF SSNSPALFPW 840
  841 FTPGSQTEKG RKKDTAPEEL SKDRDADKSV EKDKSRERDR EREKENKRES RKEKRKKGSD 900
  901 IQSSSALYPV GRVSKEKVAG EDVGTSSSAK KATGRKKSSS LDSGADIAPV TLGDTTAVKA 960
  961 KILIKKGRGN LEKNNLDLGP TAPSLEKEKT LCLSTPSPST VKHSTSSIGS MLAQADKLPM1020
 1021 TDKRVASLLK KAKAQLCKIE KSKSLKQTDQ PKAQGQESDS SETSVRGPRI KHVCRRAAVA1080
 1081 LGRKRAVFPD DMPTLSALPW EEREKILSSM GNDDKSSIAG SEDAEPLAPP IKPIKPVTRN1140
 1141 KAPQEPPVKK GRRSRRCGQC PGCQVPEDCG VCTNCLDKPK FGGRNIKKQC CKMRKCQNLQ1200
 1201 WMPSKAYLQK QTKAVKKKEK KSKATEKKES KESTVVKSSL ESAQKAAPPV REEPAPKKSS1260
 1261 SEPPPRKPVE EKTEEGGAPA PAPAPEPKQA STPASRKSSK QVSQPAAVVP PQPPSTALQK1320
 1321 KEAPKAIPSE PKKKQPPPPE SGPEQSKQKK VAPRPSIPVK QKPKDKEKPP PVSKQENAGT1380
 1381 LNILNPLLNG ISSKQKIPAD GVHRIRVDFK EDCEAENVWE MGGLGILTSV PITPRVVCFL1440
 1441 CASSGHVEFV YCQVCCEPFH KFCLEENERP LEDQLENWCC RRCKFCHVCG RQHQATKQLL1500
 1501 ECNKCRNSYH PECLGPNYPT KPTKKKKVWI CTKCVRCKSC GSTTPGKGWD AQWSHDFSLC1560
 1561 HDCAKLFAKG NFCPLCDKCY DDDDYESKMM QCGKCDRWVH SKCEGLSGTE DEMYEILSNL1620
 1621 PESVAYTCVN CTERHPAEWR LALEKELQAS LKQVLTALLN SRTTSHLLRY RQAAKPPDLN1680
 1681 PETEESIPSR SSPEGPDPPV LTEVSKQDEQ QPLDLEGVKK KMDQGNYVSV LEFSDDIVKI1740
 1741 IQAAINSDGG QPEIKKANSM VKSFFIRQME RVFPWFSVKK SRFWEPNKVS NNSGMLPNAV1800
 1801 LPPSLDHNYA QWQEREESSH TEQPPLMKKI IPAPKPKGPG EPDSPTPLHP PTPPILSTDR1860
 1861 SREDSPELHP PPGIDDNRQC ALCLMYGDDS ANDAGRLLYI GQNEWTHVNC ALWSAEVFED1920
 1921 DDGSLKNVHM AVIRGKQLRC EFCQKPGATV GCCLTSCTSN YHFMCSRAKN CVFLDDKKVY1980
 1981 CQRHRDLIKG EVVPENGFEV FRRVFVDFEG ISLRRKFLNG LEPESVHVMI GSMTIDCLGI2040
 2041 LNDLSDCEDK LFPIGYQCSR VYWSTTDARK RCVYTCKIME CRPPVVEPDI NSTVEHDDNR2100
 2101 TIAHSPSSFI EASCKDSQST AAILSPPSPD RPRSQASSSC YCHVISKVPR IRTPSYSPTQ2160
 2161 RSPGCRPLPS AGSPTPTTHE IVTVGDPLLS SGLRSIGSRR HSTSSLSPLR SKLRIMSPVR2220
 2221 SGSVYSRSSV SSVPSLGTAT DPESSAKATD RAGPLNSSAN LGHSTPVSSG SQRTVVTGGS2280
 2281 KTSHLDGSSS SGVKRSSASD LAPKGSSLKG EKNRTPGSKS TDGSAHNTAY SGIPKLAPQV2340
 2341 LNAAPGELNV SKIGTFAEPS TVPFSKETVS YPQLHLRGQR SDRDQHMDST QSVKPSPNED2400
 2401 GEIKTLKLPG MGHRPSILHE HVGSSSRDRR QKGKKSSKET CKEKHSSKSF LEPGQVTTGE2460
 2461 EGNLKPEFAD EVLTPGFLGQ RPCNNVSSDK TGDKILPLSG VPKGQSTQVE GSSKELQAPR2520
 2521 KCSVKVTPLK MESENQSKNT QKESGPGSPA HMESACPAEP ASASRSPGAG PGVQPSPNNT2580
 2581 SSQDPQSNNY QNLPEQDRNL MIPDGPKPQE DGSFKRRYPR RSARARSNMF FGLTPLYGVR2640
 2641 SYGEEDIPFY SSSTGKKRGK RSAEGQVDGA DDLSTSDEDD LYYYNFTRTV ISSGGDERLA2700
 2701 SHNLFREEEQ CDLPKISQLD GVDDGTESDT SVTATSRKSS QIPKRNGKEN GTENLKIDRP2760
 2761 EDAGEKEHVI KSAVGHKNEP KLDNCHSVSR VKAQGQDSLE AQLSSLESSR RVHTSTPSDK2820
 2821 NLLDTYNTEL LKSDSDNNNS DDCGNILPSD IMDFVLKNTP SMQALGESPE SSSSELLTLG2880
 2881 EGLGLDSNRE KDMGLFEVFS QQLPATEPVD SSVSSSISAE EQFELPLELP SDLSVLTTRS2940
 2941 PTVPSQNSSR LAVISDSGEK RVTITEKSVT STEGDPALLS PGVDPAPEGH MTPDHFIQGH3000
 3001 MDADHISSPP CGSVEQGHGN NQDLTRNSST PGLQVPVSPT VPIQNQKYVP NSTDSPGPSQ3060
 3061 ISNAAVQTTP PHLKPATEKL IVVNQNMQPL YVLQTLPNGV TQKIQLTSPV SSTPNVMETN3120
 3121 TSVLGPMGSG LTLTTGLNPS LPPSQSLFPP ASKGLLSMPH HQHLHSFPAA AQSSFPPNIS3180
 3181 SPPSGLLIGV QPPPDPQLLG SEANQRTDLT TTVTTPSSGL KKRPISRLHT RKNKKLAPSS3240
 3241 APSNIAPSDV VSNMTLINFT PSQLSNHPSL LDLGSLNPSS HRTVPNIIKR SKSGIMYFEQ3300
 3301 APLLPPQSVG GTTATGAGSS TISQDTSHLT SGPVSALASG SSVLNVVSMQ TTTTPTSSTS3360
 3361 VPGHVTLANQ RLLGTPDIGS ISHLLIKASH QSLGIQDQPV ALPQSSGMFP QLGTSQTPSA3420
 3421 AAMTAASSIC VLPSSQTAGM TAASPPREAE EQYKLQRVNQ LLAGKTGTLS LQRDRDPDSA3480
 3481 PGTQPSNFTQ TAEAPNGVRL EQNKTLPSAK QASSTSPGSS PSSGQQSGSS SVPGPTKPKP3540
 3541 KVKRIQLPLD KGSGKKHKVS HLRTSSEAHI PHREANPAPQ PSVKRTPRAD REQQEAAGVE3600
 3601 QPSQKECGQP AGPATALPEI QATQNPANEQ ENAEPKAVEE EESSFSSPLM LWLQQEQKRK3660
 3661 ESITERKPKK GLVFEISSDD GFQICAESIE DAWKSLTDKV QEARSNARLK QLSFAGVNGL3720
 3721 RMLGILHDAV VFLIEQLSGA KHCRNYKFRF HKPEEANEPP LNPHGSARAE VHLRKSAFDM3780
 3781 FNFLASKHRQ PPEYNPNDEE EEEVQLKSAR RATSMDLPMP MRFRHLKKTS KEAVGVYRSP3840
 3841 IHGRGLFCKR NIDAGEMVIE YAGNVIRSIQ TDKREKYYDS KGIGCYMFRI DDSEVVDATM3900
 3901 HGNAARFINH SCEPNCYSRV INIDGQKHIV IFAMRKIYRG EELTYDYKFP IEDASNKLPC3960
 3961 NCGAKKCRKF LN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.76

Protein Overview: gi|109484612

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: