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Protein Overview: gi|109483405

General Information:
Name(s) found: gi|109483405 [NCBI NR]
Description(s) found:
Found 2 descriptions.
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  • gi|109483405|ref|XP_236194.4| PREDICTED: similar to Zinc finger protein HRX (ALL-1) [Rattus norvegicus] [NCBI NR]
    • Organism: Rattus norvegicus
    Length: 3707 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IEA]
    nuclear part [UNKNOWN]
    histone methyltransferase complex [UNKNOWN][IEA]
    cellular_component [ND]
    MLL1 complex [UNKNOWN]
    Biological Process: chromatin modification [IEA]
    biological_process [ND]
    protein complex assembly [UNKNOWN]
    embryonic hemopoiesis [UNKNOWN]
    negative regulation of cell proliferation [UNKNOWN]
    anterior/posterior pattern formation [UNKNOWN]
    regulation of transcription, DNA-dependent [IEA]
    positive regulation of transcription from RNA polymerase II promoter [UNKNOWN]
    histone H4-K16 acetylation [UNKNOWN]
    DNA methylation [UNKNOWN]
    positive regulation of transcription, DNA-dependent [UNKNOWN]
    regulation of histone H3-K4 methylation [UNKNOWN]
    histone H3-K4 methylation [UNKNOWN]
    Molecular Function: histone methyltransferase activity (H3-K4 specific) [UNKNOWN][IEA]
    DNA binding [IEA]
    zinc ion binding [UNKNOWN][IEA]
    identical protein binding [UNKNOWN]
    protein binding [UNKNOWN][IEA]
    protein homodimerization activity [UNKNOWN]
    histone acetyl-lysine binding [UNKNOWN]
    unmethylated CpG binding [UNKNOWN]
    chromatin binding [UNKNOWN]
    molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFQQATKIKK LRAGKLSPLK SKFKTGKLQI GRKGVQIVRR RGRPPSTERI KTPSGLLINS  60
   61 ELEKPQKVRK DKEGTPPLTK EDKTVVRQSP RRIKPVRIIP SSKRTDATIA KQLLQRAKKG 120
  121 AQKKIEKEAA QLQGRKVKTQ VKNIRQFIMP VVSAISSRII KTPRRFIEDE DYDPPIKIAR 180
  181 LESTPNSRFS ATSCGSSEKS SAASQHSSQM SSDSSRSSSP SIDTTSDSQA SEEIQALPEE 240
  241 RSNTPEVHTP LPISQSPENE SNDRRGRRYS MSERSFGSRT TKKLPTLQSA PQQQTSSSPP 300
  301 PPLLTPPPPL QPASGISDHT PWLMPPTIPL ASPFLPASAA PMQGKRKSIL REPTFRWTSL 360
  361 KHSRSEPQYF SSAKYAKEGL IRKPIFDNFR PPPLTPEDVG FASGFSASGS AASARLFSPL 420
  421 HSGTRFDIHK RSPILRAPRF TPSEAHSRIF ESVTLPSNRT SSGASSSGVS NRKRKRKVFS 480
  481 PIRSEPRSPS HSMRTRSGRL STSELSPLTP PSSVSSSLSI PVSPLAASAL NPTFTFPSHS 540
  541 LTQSGESTEK SQRARKQTSA PAEPFSSNSP ALFPWFTPGS QTEKGRKKDT APEELSKDRD 600
  601 ADKSVEKDKS RERDREREKE NKRESRKEKR KKGSDIQSSS ALYPVGRVSK EKVAGEDVGT 660
  661 SSSAKKATGR KKSSSLDSGA DIAPVTLGDT TAVKAKILIK KGRGNLEKNN LDLGPTAPSL 720
  721 EKEKTLCLST PSPSTVKHST SSIGSMLAQA DKLPMTDKRV ASLLKKAKAQ LCKIEKSKSL 780
  781 KQTDQPKAQG QESDSSETSV RGPRIKHVCR RAAVALGRKR AVFPDDMPTL SALPWEEREK 840
  841 ILSSMGNDDK SSIAGSEDAE PLAPPIKPIK PVTRNKAPQE PPVKKGRRSR RCGQCPGCQV 900
  901 PEDCGVCTNC LDKPKFGGRN IKKQCCKMRK CQNLQWMPSK AYLQKQTKAV KKKEKKSKAT 960
  961 EKKESKESTV VKSSLESAQK AAPPVREEPA PKKSSSEPPP RKPVEEKTEE GGAPAPAPAP1020
 1021 EPKQASTPAS RKSSKQVSQP AAVVPPQPPS TALQKKEAPK AIPSEPKKKQ PPPPESGPEQ1080
 1081 SKQKKVAPRP SIPVKQKPKD KEKPPPVSKQ ENAGTLNILN PLLNGISSKQ KIPADGVHRI1140
 1141 RVDFKEDCEA ENVWEMGGLG ILTSVPITPR VVCFLCASSG HVEFVYCQVC CEPFHKFCLE1200
 1201 ENERPLEDQL ENWCCRRCKF CHVCGRQHQA TKQLLECNKC RNSYHPECLG PNYPTKPTKK1260
 1261 KKVWICTKCV RCKSCGSTTP GKGWDAQWSH DFSLCHDCAK LFAKGNFCPL CDKCYDDDDY1320
 1321 ESKMMQCGKC DRWVHSKCEG LSGTEDEMYE ILSNLPESVA YTCVNCTERH PAEWRLALEK1380
 1381 ELQASLKQVL TALLNSRTTS HLLRYRQAAK PPDLNPETEE SIPSRSSPEG PDPPVLTEVS1440
 1441 KQDEQQPLDL EGVKKKMDQG NYVSVLEFSD DIVKIIQAAI NSDGGQPEIK KANSMVKSFF1500
 1501 IRQMERVFPW FSVKKSRFWE PNKVSNNSGM LPNAVLPPSL DHNYAQWQER EESSHTEQPP1560
 1561 LMKKIIPAPK PKGPGEPDSP TPLHPPTPPI LSTDRSREDS PELHPPPGID DNRQCALCLM1620
 1621 YGDDSANDAG RLLYIGQNEW THVNCALWSA EVFEDDDGSL KNVHMAVIRG KQLRCEFCQK1680
 1681 PGATVGCCLT SCTSNYHFMC SRAKNCVFLD DKKVYCQRHR DLIKGEVVPE NGFEVFRRVF1740
 1741 VDFEGISLRR KFLNGLEPES VHVMIGSMTI DCLGILNDLS DCEDKLFPIG YQCSRVYWST1800
 1801 TDARKRCVYT CKIMECRPPV VEPDINSTVE HDDNRTIAHS PSSFIEASCK DSQSTAAILS1860
 1861 PPSPDRPRSQ ASSSCYCHVI SKVPRIRTPS YSPTQRSPGC RPLPSAGSPT PTTHEIVTVG1920
 1921 DPLLSSGLRS IGSRRHSTSS LSPLRSKLRI MSPVRSGSVY SRSSVSSVPS LGTATDPESS1980
 1981 AKATDRAGPL NSSANLGHST PVSSGSQRTV VTGGSKTSHL DGSSSSGVKR SSASDLAPKG2040
 2041 SSLKGEKNRT PGSKSTDGSA HNTAYSGIPK LAPQVLNAAP GELNVSKIGT FAEPSTVPFS2100
 2101 KETVSYPQLH LRGQRSDRDQ HMDSTQSVKP SPNEDGEIKT LKLPGMGHRP SILHEHVGSS2160
 2161 SRDRRQKGKK SSKETCKEKH SSKSFLEPGQ VTTGEEGNLK PEFADEVLTP GFLGQRPCNN2220
 2221 VSSDKTGDKI LPLSGVPKGQ STQVEGSSKE LQAPRKCSVK VTPLKMESEN QSKNTQKESG2280
 2281 PGSPAHMESA CPAEPASASR SPGAGPGVQP SPNNTSSQDP QSNNYQNLPE QDRNLMIPDG2340
 2341 PKPQEDGSFK RRYPRRSARA RSNMFFGLTP LYGVRSYGEE DIPFYSSSTG KKRGKRSAEG2400
 2401 QVDGADDLST SDEDDLYYYN FTRTVISSGG DERLASHNLF REEEQCDLPK ISQLDGVDDG2460
 2461 TESDTSVTAT SRKSSQIPKR NGKENGTENL KIDRPEDAGE KEHVIKSAVG HKNEPKLDNC2520
 2521 HSVSRVKAQG QDSLEAQLSS LESSRRVHTS TPSDKNLLDT YNTELLKSDS DNNNSDDCGN2580
 2581 ILPSDIMDFV LKNTPSMQAL GESPESSSSE LLTLGEGLGL DSNREKDMGL FEVFSQQLPA2640
 2641 TEPVDSSVSS SISAEEQFEL PLELPSDLSV LTTRSPTVPS QNSSRLAVIS DSGEKRVTIT2700
 2701 EKSVTSTEGD PALLSPGVDP APEGHMTPDH FIQGHMDADH ISSPPCGSVE QGHGNNQDLT2760
 2761 RNSSTPGLQV PVSPTVPIQN QKYVPNSTDS PGPSQISNAA VQTTPPHLKP ATEKLIVVNQ2820
 2821 NMQPLYVLQT LPNGVTQKIQ LTSPVSSTPN VMETNTSVLG PMGSGLTLTT GLNPSLPPSQ2880
 2881 SLFPPASKGL LSMPHHQHLH SFPAAAQSSF PPNISSPPSG LLIGVQPPPD PQLLGSEANQ2940
 2941 RTDLTTTVTT PSSGLKKRPI SRLHTRKNKK LAPSSAPSNI APSDVVSNMT LINFTPSQLS3000
 3001 NHPSLLDLGS LNPSSHRTVP NIIKRSKSGI MYFEQAPLLP PQSVGGTTAT GAGSSTISQD3060
 3061 TSHLTSGPVS ALASGSSVLN VVSMQTTTTP TSSTSVPGHV TLANQRLLGT PDIGSISHLL3120
 3121 IKASHQSLGI QDQPVALPQS SGMFPQLGTS QTPSAAAMTA ASSICVLPSS QTAGMTAASP3180
 3181 PREAEEQYKL QRVNQLLAGK TGTLSLQRDR DPDSAPGTQP SNFTQTAEAP NGVRLEQNKT3240
 3241 LPSAKQASST SPGSSPSSGQ QSGSSSVPGP TKPKPKVKRI QLPLDKGSGK KHKVSHLRTS3300
 3301 SEAHIPHREA NPAPQPSVKR TPRADREQQE AAGVEQPSQK ECGQPAGPAT ALPEIQATQN3360
 3361 PANEQENAEP KAVEEEESSF SSPLMLWLQQ EQKRKESITE RKPKKGLVFE ISSDDGFQIC3420
 3421 AESIEDAWKS LTDKVQEARS NARLKQLSFA GVNGLRMLGI LHDAVVFLIE QLSGAKHCRN3480
 3481 YKFRFHKPEE ANEPPLNPHG SARAEVHLRK SAFDMFNFLA SKHRQPPEYN PNDEEEEEVQ3540
 3541 LKSARRATSM DLPMPMRFRH LKKTSKEAVG VYRSPIHGRG LFCKRNIDAG EMVIEYAGNV3600
 3601 IRSIQTDKRE KYYDSKGIGC YMFRIDDSEV VDATMHGNAA RFINHSCEPN CYSRVINIDG3660
 3661 QKHIVIFAMR KIYRGEELTY DYKFPIEDAS NKLPCNCGAK KCRKFLN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle