Protein Overview: gi|149044501, gi...

General Information:
Name(s) found:	gi\|157787147 [NCBI NR] gi\|149044501 [NCBI NR] gi\|109476758 [NCBI NR] gi\|109475128 [NCBI NR]
Description(s) found: SHOW ONLY BEST	gi\|157787147\|ref\|NP_001099207.1\| TEK tyrosine kinase, endothelial [Rattus norvegicus] [NCBI NR] gi\|149044501\|gb\|EDL97760.1\| endothelial-specific receptor tyrosine kinase [Rattus norvegicus] [NCBI NR] gi\|109476758\|ref\|XP_001054314.1\| PREDICTED: similar to Angiopoietin-1 receptor precursor (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antig [NCBI NR] gi\|109475128\|ref\|XP_342864.3\| PREDICTED: similar to Angiopoietin-1 receptor precursor (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen) [NCBI NR] endothelial-specific receptor tyrosine kinase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] TEK tyrosine kinase, endothelial [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] PREDICTED: similar to Angiopoietin-1 receptor precursor (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen) [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Tek TEK tyrosine kinase, endothelial [rat-ipi-250309-contam.fasta] angiopoietin-1 receptor [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Endothelial-specific receptor tyrosine kinase OS=Rattus norvegicus GN=Tek [011711_HMR.fasta] Endothelial-specific receptor tyrosine kinase OS=Rattus norvegicus GN=Tek PE=4 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta] Endothelial-specific receptor tyrosine kinase OS=Rattus norvegicus GN=Tek PE=1 SV=1 [RAT.fasta.20160308]
Organism:	Rattus norvegicus
Length:	1120 amino acids
Gene Ontology:
Cellular Component:	integral to plasma membrane [IEA] microvillus [UNKNOWN] membrane raft [UNKNOWN] cellular_component [ND] basolateral plasma membrane [UNKNOWN] plasma membrane [UNKNOWN] apical plasma membrane [UNKNOWN] cell surface [UNKNOWN]
Biological Process:	response to estrogen stimulus [IDA] hemopoiesis [UNKNOWN] regulation of angiogenesis [UNKNOWN] response to cAMP [IEP] vasculogenesis [TAS] positive regulation of cell adhesion [UNKNOWN] protein amino acid phosphorylation [IEA] positive regulation of angiogenesis [IMP][TAS] response to hypoxia [IEP] anti-apoptosis [UNKNOWN] angiogenesis [UNKNOWN][IEP][TAS] positive regulation of peptidyl-serine phosphorylation [UNKNOWN] cell-matrix adhesion [UNKNOWN] cell-cell adhesion [UNKNOWN] response to organic substance [IEP] transmembrane receptor protein tyrosine kinase signaling pathway [IEA] response to peptide hormone stimulus [IEP] regulation of cell proliferation [IEA] intracellular signaling pathway [IDA] Tie receptor signaling pathway [TAS] positive regulation of ERK1 and ERK2 cascade [UNKNOWN] endochondral ossification [IEP] organ regeneration [IEP] regulation of cell migration [UNKNOWN] protein oligomerization [UNKNOWN] positive regulation of protein kinase B signaling cascade [UNKNOWN]
Molecular Function:	ATP binding [IEA] protein tyrosine kinase activity [UNKNOWN] growth factor binding [IPI] protein binding [UNKNOWN][IEA] transmembrane receptor protein tyrosine kinase activity [IEA] receptor signaling protein tyrosine kinase activity [TAS] receptor activity [UNKNOWN][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSLAGLVLC GVSLLLYGLV EGAMDLILIN SLPLVSDAET SLTCIASGWH PHEPITIGRD  60
   61 FEALMNQHQD PLEVTQDVTR EWAKKVVWKR EKASKINGAY FCEGRVRGQA IRIRTMKMRQ 120
  121 QASFLPATLT MTVDRGDNVN ISFKKVLIKE EDAVIYKNGS FIHSVPRHEV PDILEVHLPH 180
  181 AQPQDAGVYS ARYIGGNLFT SAFTRLIVRR CEAQKWGPDC NRPCTTCKNN GVCHEDTGEC 240
  241 ICPPGFMGRT CEKACEPHTF GRTCKERCSG SEGCKSYVFC LPDPYGCSCA TGWRGLQCNE 300
  301 ACPYGHYGPD CKLRCHCTNE EMCDRFQGCL CSQGWQGLQC EKEGRPRMTP QIEDLPDHIE 360
  361 VNSGKFNPIC KASGWPLPTS EEMTLVKPDG TVLQPNDFNH TDHFSVAIFT VNRILPPDSG 420
  421 VWVCSVNTVA GMVEKPFNIS VKVLPEPLHA PNVIDTGHNF AIINISSEPY FGDGPIKSKK 480
  481 LFYKPVNQAW KYIQVMNEIV TLNYLEPRTD YELCVQLVRP GEGGEGHPGP VRRFTTASIG 540
  541 LPPPRGLSLL PKSQTALNLT WQPIFTSSED EFYVEVERWS QQTRSDQQNI KVPGNLTSVL 600
  601 LNNLLPREQY SVRARVNTKA QGEWSEELRA WTLSDILPPQ PENIKITNIT DYTALVSWTI 660
  661 VDGYSISSII IRYKVQGKNE DQHIDVKIKN ATITQYQLKG LEPETTYHVD IFAENNIGSS 720
  721 NPAFSQEIRT LPAPKDLGGG KMLLIAILGS AGMTCITVLL AFLIMLQLKR ANVQRRMAQA 780
  781 FQNVREEPAV QFNSGTLALN RKAKNNPDPT IYPVLDWNDI KFQDVIGEGN FGQVLKARIK 840
  841 KDGLRMDAAI KRMKEYASKD DHRDFAGELE VLCKLGHHPN IINLLGACEH RGYLYLAIEY 900
  901 APHGNLLDFL RKSRVLETDP AFAIANSTAS TLSSQQLLHF AADVARGMDY LSQKQFIHRD 960
  961 LAARNILVGE NYIAKIADFG LSRGQEVYVK KTMGRLPVRW MAIESLNYSV YTTNSDVWSY1020
 1021 GVLLWEIVSL GGTPYCGMTC AELYEKLPQG YRLEKPLNCD DEVYDLMRQC WREKPYERPS1080
 1081 FAQILVSLNR MLEERKTYVN TTLYEKFTYA GIDCSAEEAA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: gi|149044501, gi...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: