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Protein Overview: GPI

General Information:
Name(s) found: GPI [HGNC (HUGO)]
Description(s) found:
Found 45 descriptions.
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  • glucose-6-phosphate isomerase [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 558 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAALTRDPQF QKLQQWYREH RSELNLRRLF DANKDRFNHF SLTLNTNHGH ILVDYSKNLV  60
   61 TEDVMRMLVD LAKSRGVEAA RERMFNGEKI NYTEGRAVLH VALRNRSNTP ILVDGKDVMP 120
  121 EVNKVLDKMK SFCQRVRSGD WKGYTGKTIT DVINIGIGGS DLGPLMVTEA LKPYSSGGPR 180
  181 VWYVSNIDGT HIAKTLAQLN PESSLFIIAS KTFTTQETIT NAETAKEWFL QAAKDPSAVA 240
  241 KHFVALSTNT TKVKEFGIDP QNMFEFWDWV GGRYSLWSAI GLSIALHVGF DNFEQLLSGA 300
  301 HWMDQHFRTT PLEKNAPVLL ALLGIWYINC FGCETHAMLP YDQYLHRFAA YFQQGDMESN 360
  361 GKYITKSGTR VDHQTGPIVW GEPGTNGQHA FYQLIHQGTK MIPCDFLIPV QTQHPIRKGL 420
  421 HHKILLANFL AQTEALMRGK STEEARKELQ AAGKSPEDLE RLLPHKVFEG NRPTNSIVFT 480
  481 KLTPFMLGAL VAMYEHKIFV QGIIWDINSF DQWGVELGKQ LAKKIEPELD GSAQVTSHDA 540
  541 STNGLINFIK QQREARVQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..558] PSI-BLAST 1000.0 Phosphoglucose isomerase, PGI

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • glucose-6-phosphate isomerase activity
    		•  3.62042557708076 bayes_pls_golite062009
  • intramolecular oxidoreductase activity
    		•  2.12646274924126 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, interconverting aldoses and ketoses
    		•  1.62962150339138 bayes_pls_golite062009
  • catalytic activity
    		•  1.5278037255884 bayes_pls_golite062009
  • sugar binding
    		•  1.40175307923331 bayes_pls_golite062009
  • glutamine-fructose-6-phosphate transaminase (isomerizing) activity
    		•  1.11549102314657 bayes_pls_golite062009
  • binding
    		•  1.0425673151455 bayes_pls_golite062009
  • D-sedoheptulose 7-phosphate isomerase activity
    		•  0.969046173332955 bayes_pls_golite062009
  • isomerase activity
    		•  0.875614547872629 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.5730945843207 bayes_pls_golite062009
  • protein binding
    		•  0.152745336606766 bayes_pls_golite062009
  • transferase activity
    		•  0.0523744832826621 bayes_pls_golite062009
  • transferase activity, transferring nitrogenous groups
    		•  0.0239994594084577 bayes_pls_golite062009
  • transaminase activity
    		•  0.00531525548288503 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.73

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle